Iovance Biotherapeutics (IOVA) Operating Income (2010 - 2026)
Iovance Biotherapeutics (IOVA) posted quarterly Operating Income of -$81.0 million for Q1 2026, up 33.14% year-over-year from -$60.9 million in Q1 2025, and down 10.32% quarter-over-quarter from -$73.5 million in Q4 2025.
Iovance Biotherapeutics (IOVA) Operating Income (2010 - 2026) Analysis & Trends
Iovance Biotherapeutics (IOVA) has reported Operating Income for 17 consecutive years, with -$81.0 million the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Income rose 33.14% year-over-year to -$81.0 million; the TTM figure through Mar 2026 stood at -$363.2 million (up 8.93% YoY), while the FY2025 annual figure was -$403.4 million, down 2.04% from the prior year.
- Operating Income slipped to -$81.0 million in Q1 2026 per IOVA's latest filing, from -$73.5 million in the prior quarter.
- Across five years, Operating Income topped out at -$73.5 million in Q4 2025 and bottomed at -$121.3 million in Q4 2023.
- Historically, Operating Income has averaged -$102.3 million across 5 years, with a median of -$101.9 million in 2024.
- Annual changes were most pronounced in 2022 — Operating Income fell 22.48% — and 2026, when it surged 33.14%.
- Iovance Biotherapeutics' Operating Income stood at -$107.0 million in 2022, then fell by 13.29% to -$121.3 million in 2023, then grew by 28.6% to -$86.6 million in 2024, then rose by 15.15% to -$73.5 million in 2025, then decreased by 10.32% to -$81.0 million in 2026.
- Business Quant data shows IOVA's Operating Income at -$81.0 million in Q1 2026, -$73.5 million in Q4 2025, and -$94.9 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 493.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 325.05 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -3,158.03 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 133.12 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 231.44 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Iovance Biotherapeutics | 3.16 Bn | 2.86 Bn | 55.72 Mn | -51.91 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -51.91 Mn |
| Mar 31, 2026 | -81.04 Mn |
| Dec 31, 2025 | -73.46 Mn |
| Sep 30, 2025 | -94.90 Mn |
| Jun 30, 2025 | -113.77 Mn |
| Mar 31, 2025 | -121.22 Mn |
| Dec 31, 2024 | -86.58 Mn |
| Sep 30, 2024 | -89.07 Mn |
| Jun 30, 2024 | -101.91 Mn |
| Mar 31, 2024 | -117.72 Mn |
| Dec 31, 2023 | -121.26 Mn |
| Sep 30, 2023 | -118.36 Mn |
| Jun 30, 2023 | -110.09 Mn |
| Mar 31, 2023 | -110.86 Mn |
| Dec 31, 2022 | -107.04 Mn |
| Sep 30, 2022 | -100.40 Mn |
| Jun 30, 2022 | -99.73 Mn |
| Mar 31, 2022 | -91.71 Mn |
| Dec 31, 2021 | -99.47 Mn |
| Sep 30, 2021 | -86.24 Mn |