Iovance Biotherapeutics (IOVA) EBITDA Margin (2023 - 2026)
Iovance Biotherapeutics' EBITDA Margin was -42.70% in Q2 2026, up 131.90 percentage points from -174.60% a year earlier and up 58.81 percentage points from the prior quarter.
Iovance Biotherapeutics (IOVA) EBITDA Margin (2023 - 2026) Analysis & Trends
On a trailing twelve-month basis, Iovance Biotherapeutics' EBITDA Margin was -81.36% through Jun 30, 2026, up 72.26 percentage points year-over-year; for FY2025, it was -139.44%, up 78.55 percentage points from FY2024.
- In earlier years, EBITDA Margin was -217.98% in FY2024 (+36715.74 pp) and -36933.73% in FY2023.
- The Q2 2026 figure marks the highest quarterly EBITDA Margin in data going back to Q2 2023.
- Compared with a year earlier, EBITDA Margin has increased for nine straight quarters, with an average year-over-year change of +7856.51 percentage points over the last eight quarters.
- Over the past five years, the year-over-year gain in EBITDA Margin ranged from 10.23 percentage points (Q3 2025) to 43937.51 percentage points (Q2 2024).
- Per Business Quant data, IOVA's EBITDA Margin in the three quarters before Q2 2026 was -101.50% (Q1 2026), -73.25% (Q4 2025) and -127.36% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Iovance Biotherapeutics | 4.98 Bn | 3.77 Bn | 55.72 Mn | -42.70% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -42.70% |
| Mar 31, 2026 | -101.50% |
| Dec 31, 2025 | -73.25% |
| Sep 30, 2025 | -127.36% |
| Jun 30, 2025 | -174.60% |
| Mar 31, 2025 | -229.41% |
| Dec 31, 2024 | -98.55% |
| Sep 30, 2024 | -137.59% |
| Jun 30, 2024 | -300.31% |
| Mar 31, 2024 | -15,397.06% |
| Dec 31, 2023 | -23,733.82% |
| Sep 30, 2023 | -23,765.67% |
| Jun 30, 2023 | -44,237.82% |
Iovance Biotherapeutics EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=IOVA&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "IOVA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=IOVA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();