Ionis Pharmaceuticals (IONS) Total Debt (2009 - 2026)

Ionis Pharmaceuticals' (IONS) quarterly Total Debt came in at $432.5 million in Q1 2026, down 5.99% quarter-over-quarter from $460.1 million in Q4 2025.

Ionis Pharmaceuticals (IONS) Total Debt (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Total Debt history runs 18 years deep, the most recent figure standing at $432.5 million for Q1 2026.

  • On a quarterly basis, Total Debt changed N/A year-over-year to $432.5 million in Q1 2026; TTM through Mar 2026 was $432.5 million, a N/A change from a year earlier, with the FY2025 full-year figure at $460.1 million, up 786.04% from the prior year.
  • Total Debt slipped to $432.5 million in Q1 2026 per IONS's latest filing, from $460.1 million in the prior quarter.
  • Across five years, Total Debt topped out at $630.9 million in Q3 2025 and bottomed at $8.8 million in Q1 2023.
  • The 5-year median for Total Debt is $44.4 million (2024), against an average of $181.4 million.
  • Across the five-year window, Total Debt tumbled 75.44% in 2022 and jumped 1318.83% in 2025, its largest moves.
  • Year by year, Total Debt stood at $16.0 million in 2022, then soared by 439.46% to $86.2 million in 2023, then sank by 39.74% to $51.9 million in 2024, then jumped by 786.04% to $460.1 million in 2025, then declined by 5.99% to $432.5 million in 2026.
  • Per Business Quant, the three latest IONS Total Debt figures stand at $432.5 million (Q1 2026), $460.1 million (Q4 2025), and $630.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Total Debt (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - 110.96 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 959.06 Mn
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 1.99 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Ionis Pharmaceuticals 9.21 Bn 7.29 Bn 243.11 Mn 432.50 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 432.50 Mn
Dec 31, 2025 460.07 Mn
Sep 30, 2025 630.91 Mn
Jun 30, 2025 630.12 Mn
Dec 31, 2024 51.92 Mn
Sep 30, 2024 44.47 Mn
Jun 30, 2024 44.42 Mn
Mar 31, 2024 44.38 Mn
Dec 31, 2023 86.17 Mn
Mar 31, 2023 8.81 Mn
Dec 31, 2022 15.97 Mn
Sep 30, 2022 30.08 Mn
Jun 30, 2022 29.83 Mn
Mar 31, 2022 29.92 Mn
Dec 31, 2021 63.24 Mn
Sep 30, 2021 83.56 Mn
Jun 30, 2021 83.93 Mn
Mar 31, 2021 121.82 Mn
Dec 31, 2020 67.29 Mn
Sep 30, 2020 21.73 Mn