Ionis Pharmaceuticals (IONS) Return on Capital Employed [ROCE] (2010 - 2026)
Ionis Pharmaceuticals (IONS) reported Return on Capital Employed [ROCE] of -20.45% for Q2 2026, down 7.13 percentage points from -13.31% a year earlier and down 7.73 percentage points from the prior quarter.
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Analysis
Ionis Pharmaceuticals (IONS) Return on Capital Employed [ROCE] (2010 - 2026) Analysis & Trends
For FY2025, Ionis Pharmaceuticals posted Return on Capital Employed [ROCE] of -15.38%, up 2.30 percentage points from FY2024.
- Return on Capital Employed [ROCE] has a five-year change of -7.60 percentage points (FY2020 to FY2025).
- By year, Return on Capital Employed [ROCE] came in at -17.68% in FY2024 (-2.39 pp), -15.29% in FY2023 (+2.85 pp), -18.14% in FY2022 (-16.80 pp) and -1.34% in FY2021 (+6.44 pp).
- The Q2 2026 figure ranks as the lowest quarterly Return on Capital Employed [ROCE] since Q3 2023.
- Year over year, Return on Capital Employed [ROCE] gained in five of the last eight quarters, with an average year-over-year change of +0.57 percentage points.
- The high point for year-over-year Return on Capital Employed [ROCE] in five years was Q3 2022 (a gain of 13.42 percentage points); the low point was Q3 2023 (a drop of 22.66 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -12.72% (Q1 2026), -15.29% (Q4 2025) and -13.20% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 46.74% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 17.83% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 17.92% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 6.28% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 19.32% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 9.54% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 16.66% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 11.86% |
| 10 | Ionis Pharmaceuticals | 7.21 Bn | -1.68 Bn | 265.21 Mn | -20.45% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -20.45% |
| Mar 31, 2026 | -12.72% |
| Dec 31, 2025 | -15.29% |
| Sep 30, 2025 | -13.20% |
| Jun 30, 2025 | -13.31% |
| Mar 31, 2025 | -17.77% |
| Dec 31, 2024 | -17.38% |
| Sep 30, 2024 | -14.35% |
| Jun 30, 2024 | -15.07% |
| Mar 31, 2024 | -15.26% |
| Dec 31, 2023 | -14.07% |
| Sep 30, 2023 | -21.80% |
| Jun 30, 2023 | -17.86% |
| Mar 31, 2023 | -19.05% |
| Dec 31, 2022 | -18.93% |
| Sep 30, 2022 | 0.86% |
| Jun 30, 2022 | -0.37% |
| Mar 31, 2022 | 0.18% |
| Dec 31, 2021 | -1.33% |
| Sep 30, 2021 | -12.57% |
API Access
Ionis Pharmaceuticals Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=IONS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "IONS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=IONS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();