Ionis Pharmaceuticals (IONS) Retained Earnings (2009 - 2026)

Ionis Pharmaceuticals (IONS) recorded quarterly Retained Earnings of -$2.7 billion in Q1 2026, down 3.52% quarter-over-quarter from -$2.6 billion in Q4 2025, and down 13.64% on a YoY basis from -$3.2 billion in Q1 2025.

Ionis Pharmaceuticals (IONS) Retained Earnings (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Retained Earnings history runs 18 years deep, the most recent figure standing at -$2.7 billion for Q1 2026.

  • In Q1 2026, Retained Earnings fell 13.64% year-over-year to -$2.7 billion; the TTM figure through Mar 2026 stood at -$2.7 billion (down 13.64% YoY), while the FY2025 annual figure was -$2.6 billion, down 8439.79% from the prior year.
  • Retained Earnings was -$2.7 billion for Q1 2026 at Ionis Pharmaceuticals, down from -$2.6 billion in the prior quarter.
  • In the past five years, Retained Earnings ranged from a high of -$24.2 million in Q3 2024 to a low of -$2.7 billion in Q1 2026.
  • Historically, Retained Earnings has averaged -$1.5 billion across 5 years, with a median of -$1.6 billion in 2023.
  • The sharpest annual moves came in 2024 and 2025: Retained Earnings soared 98.65% in 2024, then slumped 9835.88% in 2025.
  • A 5-year view of Retained Earnings shows it stood at -$1.4 billion in 2022, then slipped by 25.62% to -$1.8 billion in 2023, then jumped by 98.28% to -$30.8 million in 2024, then plunged by 8439.79% to -$2.6 billion in 2025, then fell by 3.52% to -$2.7 billion in 2026.
  • The last three Retained Earnings figures came in at -$2.7 billion (Q1 2026), -$2.6 billion (Q4 2025), and -$2.4 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -153.89 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -211.85 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 1.00 Bn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 130.89 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -279.00 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1.88
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 14.59 Bn
9 Abivax 91.96 Bn 91.96 Bn - -838.07 Mn
10 Ionis Pharmaceuticals 12.23 Bn 10.31 Bn 243.11 Mn -2.72 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 -2.72 Bn
Dec 31, 2025 -2.63 Bn
Sep 30, 2025 -2.40 Bn
Jun 30, 2025 -27.99 Mn
Mar 31, 2025 -2.40 Bn
Dec 31, 2024 -30.81 Mn
Sep 30, 2024 -24.17 Mn
Jun 30, 2024 -2.00 Bn
Mar 31, 2024 -1.94 Bn
Dec 31, 2023 -1.80 Bn
Sep 30, 2023 -1.79 Bn
Jun 30, 2023 -1.64 Bn
Mar 31, 2023 -48.98 Mn
Dec 31, 2022 -1.43 Bn
Sep 30, 2022 -1.38 Bn
Jun 30, 2022 -1.33 Bn
Mar 31, 2022 -1.23 Bn
Dec 31, 2021 -32.67 Mn
Sep 30, 2021 -27.44 Mn
Jun 30, 2021 -25.80 Mn