Ionis Pharmaceuticals IONS
NASDAQ IONS
$58.86 +0.73 (+1.26%)
As of: Sep 4, 2026 · 12:51 PM EDT

Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026)

Ionis Pharmaceuticals (IONS) posted quarterly Profit After Tax of -$114.6 million for Q2 2026, down 192.79% year-over-year from $123.6 million in Q2 2025, and down 23.9% quarter-over-quarter from -$92.5 million in Q1 2026.

Analysis

Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Profit After Tax history runs 18 years deep, the most recent figure standing at -$114.6 million for Q2 2026.

  • In Q2 2026, Profit After Tax fell 192.79% year-over-year to -$114.6 million; the TTM figure through Jun 2026 stood at -$565.2 million (down 110.72% YoY), while the FY2025 annual figure was -$381.4 million, up 15.97% from the prior year.
  • Profit After Tax for Q2 2026 stood at -$114.6 million, down from -$92.5 million in the prior quarter.
  • The five-year high for Profit After Tax was $123.6 million in Q2 2025, with the low at -$229.4 million in Q4 2025.
  • The 5-year median for Profit After Tax is -$104.7 million (2022), against an average of -$93.2 million.
  • The sharpest annual moves came in 2024 and 2025: Profit After Tax slumped 1026.51% in 2024, then soared 286.45% in 2025.
  • Ionis Pharmaceuticals' Profit After Tax stood at -$52.4 million in 2022, then soared by 82.33% to -$9.3 million in 2023, then plunged by 1026.51% to -$104.3 million in 2024, then plunged by 119.83% to -$229.4 million in 2025, then jumped by 50.02% to -$114.6 million in 2026.
  • Business Quant data shows IONS's Profit After Tax at -$114.6 million in Q2 2026, -$92.5 million in Q1 2026, and -$229.4 million in Q4 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 139.62 Bn 131.77 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.73 Bn 77.73 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 63.53 Bn 58.35 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.23 Bn 53.09 Bn 52.00 Mn -782.00 Mn
5 Revolution Medicines 44.05 Bn 44.05 Bn - -644.37 Mn
6 BeOne Medicines 40.03 Bn 34.93 Bn 1.53 Bn 237.01 Mn
7 Alnylam Pharmaceuticals 35.50 Bn 32.19 Bn 992.69 Mn 164.49 Mn
8 Royalty Pharma 28.52 Bn 27.68 Bn - 81.49 Mn
9 Insmed 27.46 Bn 26.30 Bn 358.27 Mn -16.62 Mn
10 Ionis Pharmaceuticals 9.74 Bn 7.68 Bn 265.21 Mn -114.65 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -114.65 Mn
Mar 31, 2026 -92.53 Mn
Dec 31, 2025 -229.39 Mn
Sep 30, 2025 -128.61 Mn
Jun 30, 2025 123.55 Mn
Mar 31, 2025 -146.94 Mn
Dec 31, 2024 -104.35 Mn
Sep 30, 2024 -140.48 Mn
Jun 30, 2024 -66.27 Mn
Mar 31, 2024 -142.80 Mn
Dec 31, 2023 -9.26 Mn
Sep 30, 2023 -147.41 Mn
Jun 30, 2023 -85.29 Mn
Mar 31, 2023 -124.32 Mn
Dec 31, 2022 -52.43 Mn
Sep 30, 2022 -46.99 Mn
Jun 30, 2022 -105.14 Mn
Mar 31, 2022 -65.17 Mn
Dec 31, 2021 224.61 Mn
Sep 30, 2021 -82.47 Mn