Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026)

Ionis Pharmaceuticals (IONS) recorded quarterly Profit After Tax of -$92.5 million in Q1 2026, up 59.66% quarter-over-quarter from -$229.4 million in Q4 2025, and up 37.03% on a YoY basis from -$67.5 million in Q1 2025.

Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Profit After Tax history runs 18 years deep, the most recent figure standing at -$92.5 million for Q1 2026.

  • In Q1 2026, Profit After Tax rose 37.03% year-over-year to -$92.5 million; the TTM figure through Mar 2026 stood at -$327.0 million (up 28.61% YoY), while the FY2025 annual figure was -$381.4 million, up 15.97% from the prior year.
  • Profit After Tax was -$92.5 million for Q1 2026 at Ionis Pharmaceuticals, up from -$229.4 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of $123.6 million in Q2 2025 to a low of -$229.4 million in Q4 2025.
  • Historically, Profit After Tax has averaged -$92.0 million across 5 years, with a median of -$104.3 million in 2024.
  • The sharpest annual moves came in 2024 and 2025: Profit After Tax tumbled 1026.51% in 2024, then jumped 286.45% in 2025.
  • A 5-year view of Profit After Tax shows it stood at -$52.4 million in 2022, then jumped by 82.33% to -$9.3 million in 2023, then sank by 1026.51% to -$104.3 million in 2024, then sank by 119.83% to -$229.4 million in 2025, then jumped by 59.66% to -$92.5 million in 2026.
  • The last three Profit After Tax figures came in at -$92.5 million (Q1 2026), -$229.4 million (Q4 2025), and -$128.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 30.90 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.63 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -753,254.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.03 Bn
9 Abivax 91.96 Bn 91.96 Bn - -56.74 Mn
10 Ionis Pharmaceuticals 12.23 Bn 10.31 Bn 243.11 Mn -92.53 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -92.53 Mn
Dec 31, 2025 -229.39 Mn
Sep 30, 2025 -128.61 Mn
Jun 30, 2025 123.55 Mn
Mar 31, 2025 -146.94 Mn
Dec 31, 2024 -104.35 Mn
Sep 30, 2024 -140.48 Mn
Jun 30, 2024 -66.27 Mn
Mar 31, 2024 -142.80 Mn
Dec 31, 2023 -9.26 Mn
Sep 30, 2023 -147.41 Mn
Jun 30, 2023 -85.29 Mn
Mar 31, 2023 -124.32 Mn
Dec 31, 2022 -52.43 Mn
Sep 30, 2022 -46.99 Mn
Jun 30, 2022 -105.14 Mn
Mar 31, 2022 -65.17 Mn
Dec 31, 2021 224.61 Mn
Sep 30, 2021 -82.47 Mn
Jun 30, 2021 -80.88 Mn