Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026)

Ionis Pharmaceuticals' (IONS) quarterly Profit After Tax came in at -$92.5 million in Q1 2026, up 37.03% year-on-year from -$67.5 million in Q1 2025, and up 59.66% quarter-over-quarter from -$229.4 million in Q4 2025.

Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Profit After Tax history runs 18 years deep, the most recent figure standing at -$92.5 million for Q1 2026.

  • On a quarterly basis, Profit After Tax rose 37.03% year-over-year to -$92.5 million in Q1 2026; TTM through Mar 2026 was -$327.0 million, a 28.61% increase from a year earlier, with the FY2025 full-year figure at -$381.4 million, up 15.97% from the prior year.
  • Profit After Tax grew to -$92.5 million in Q1 2026 per IONS's latest filing, from -$229.4 million in the prior quarter.
  • Across five years, Profit After Tax topped out at $123.6 million in Q2 2025 and bottomed at -$229.4 million in Q4 2025.
  • The 5-year median for Profit After Tax is -$104.3 million (2024), against an average of -$92.0 million.
  • Across the five-year window, Profit After Tax tumbled 1026.51% in 2024 and soared 286.45% in 2025, its largest moves.
  • Year by year, Profit After Tax stood at -$52.4 million in 2022, then jumped by 82.33% to -$9.3 million in 2023, then tumbled by 1026.51% to -$104.3 million in 2024, then tumbled by 119.83% to -$229.4 million in 2025, then jumped by 59.66% to -$92.5 million in 2026.
  • Per Business Quant, the three latest IONS Profit After Tax figures stand at -$92.5 million (Q1 2026), -$229.4 million (Q4 2025), and -$128.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.84 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -14.46 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 227.36 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -65.60 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 498.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 Ionis Pharmaceuticals 9.35 Bn 7.43 Bn 243.11 Mn -92.53 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -92.53 Mn
Dec 31, 2025 -229.39 Mn
Sep 30, 2025 -128.61 Mn
Jun 30, 2025 123.55 Mn
Mar 31, 2025 -146.94 Mn
Dec 31, 2024 -104.35 Mn
Sep 30, 2024 -140.48 Mn
Jun 30, 2024 -66.27 Mn
Mar 31, 2024 -142.80 Mn
Dec 31, 2023 -9.26 Mn
Sep 30, 2023 -147.41 Mn
Jun 30, 2023 -85.29 Mn
Mar 31, 2023 -124.32 Mn
Dec 31, 2022 -52.43 Mn
Sep 30, 2022 -46.99 Mn
Jun 30, 2022 -105.14 Mn
Mar 31, 2022 -65.17 Mn
Dec 31, 2021 224.61 Mn
Sep 30, 2021 -82.47 Mn
Jun 30, 2021 -80.88 Mn