Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026)
Ionis Pharmaceuticals' (IONS) quarterly Profit After Tax came in at -$92.5 million in Q1 2026, up 37.03% year-on-year from -$67.5 million in Q1 2025, and up 59.66% quarter-over-quarter from -$229.4 million in Q4 2025.
Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Profit After Tax history runs 18 years deep, the most recent figure standing at -$92.5 million for Q1 2026.
- On a quarterly basis, Profit After Tax rose 37.03% year-over-year to -$92.5 million in Q1 2026; TTM through Mar 2026 was -$327.0 million, a 28.61% increase from a year earlier, with the FY2025 full-year figure at -$381.4 million, up 15.97% from the prior year.
- Profit After Tax grew to -$92.5 million in Q1 2026 per IONS's latest filing, from -$229.4 million in the prior quarter.
- Across five years, Profit After Tax topped out at $123.6 million in Q2 2025 and bottomed at -$229.4 million in Q4 2025.
- The 5-year median for Profit After Tax is -$104.3 million (2024), against an average of -$92.0 million.
- Across the five-year window, Profit After Tax tumbled 1026.51% in 2024 and soared 286.45% in 2025, its largest moves.
- Year by year, Profit After Tax stood at -$52.4 million in 2022, then jumped by 82.33% to -$9.3 million in 2023, then tumbled by 1026.51% to -$104.3 million in 2024, then tumbled by 119.83% to -$229.4 million in 2025, then jumped by 59.66% to -$92.5 million in 2026.
- Per Business Quant, the three latest IONS Profit After Tax figures stand at -$92.5 million (Q1 2026), -$229.4 million (Q4 2025), and -$128.6 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | PAT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -36.84 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 227.36 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.03 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -65.60 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -26.94 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 362.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -453.82 Mn |
| 10 | Ionis Pharmaceuticals | 9.21 Bn | 7.29 Bn | 243.11 Mn | -92.53 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -92.53 Mn |
| Dec 31, 2025 | -229.39 Mn |
| Sep 30, 2025 | -128.61 Mn |
| Jun 30, 2025 | 123.55 Mn |
| Mar 31, 2025 | -146.94 Mn |
| Dec 31, 2024 | -104.35 Mn |
| Sep 30, 2024 | -140.48 Mn |
| Jun 30, 2024 | -66.27 Mn |
| Mar 31, 2024 | -142.80 Mn |
| Dec 31, 2023 | -9.26 Mn |
| Sep 30, 2023 | -147.41 Mn |
| Jun 30, 2023 | -85.29 Mn |
| Mar 31, 2023 | -124.32 Mn |
| Dec 31, 2022 | -52.43 Mn |
| Sep 30, 2022 | -46.99 Mn |
| Jun 30, 2022 | -105.14 Mn |
| Mar 31, 2022 | -65.17 Mn |
| Dec 31, 2021 | 224.61 Mn |
| Sep 30, 2021 | -82.47 Mn |
| Jun 30, 2021 | -80.88 Mn |