Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026)
Ionis Pharmaceuticals (IONS) posted quarterly Profit After Tax of -$114.6 million for Q2 2026, down 192.79% year-over-year from $123.6 million in Q2 2025, and down 23.9% quarter-over-quarter from -$92.5 million in Q1 2026.
Analysis
Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Profit After Tax history runs 18 years deep, the most recent figure standing at -$114.6 million for Q2 2026.
- In Q2 2026, Profit After Tax fell 192.79% year-over-year to -$114.6 million; the TTM figure through Jun 2026 stood at -$565.2 million (down 110.72% YoY), while the FY2025 annual figure was -$381.4 million, up 15.97% from the prior year.
- Profit After Tax for Q2 2026 stood at -$114.6 million, down from -$92.5 million in the prior quarter.
- The five-year high for Profit After Tax was $123.6 million in Q2 2025, with the low at -$229.4 million in Q4 2025.
- The 5-year median for Profit After Tax is -$104.7 million (2022), against an average of -$93.2 million.
- The sharpest annual moves came in 2024 and 2025: Profit After Tax slumped 1026.51% in 2024, then soared 286.45% in 2025.
- Ionis Pharmaceuticals' Profit After Tax stood at -$52.4 million in 2022, then soared by 82.33% to -$9.3 million in 2023, then plunged by 1026.51% to -$104.3 million in 2024, then plunged by 119.83% to -$229.4 million in 2025, then jumped by 50.02% to -$114.6 million in 2026.
- Business Quant data shows IONS's Profit After Tax at -$114.6 million in Q2 2026, -$92.5 million in Q1 2026, and -$229.4 million in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | PAT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.62 Bn | 131.77 Bn | 2.84 Bn | 1.10 Bn |
| 2 | Regeneron Pharmaceuticals | 85.73 Bn | 77.73 Bn | 3.93 Bn | 1.30 Bn |
| 3 | Argenx Se | 63.53 Bn | 58.35 Bn | 1.37 Bn | 472.00 Mn |
| 4 | Moderna | 58.23 Bn | 53.09 Bn | 52.00 Mn | -782.00 Mn |
| 5 | Revolution Medicines | 44.05 Bn | 44.05 Bn | - | -644.37 Mn |
| 6 | BeOne Medicines | 40.03 Bn | 34.93 Bn | 1.53 Bn | 237.01 Mn |
| 7 | Alnylam Pharmaceuticals | 35.50 Bn | 32.19 Bn | 992.69 Mn | 164.49 Mn |
| 8 | Royalty Pharma | 28.52 Bn | 27.68 Bn | - | 81.49 Mn |
| 9 | Insmed | 27.46 Bn | 26.30 Bn | 358.27 Mn | -16.62 Mn |
| 10 | Ionis Pharmaceuticals | 9.74 Bn | 7.68 Bn | 265.21 Mn | -114.65 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -114.65 Mn |
| Mar 31, 2026 | -92.53 Mn |
| Dec 31, 2025 | -229.39 Mn |
| Sep 30, 2025 | -128.61 Mn |
| Jun 30, 2025 | 123.55 Mn |
| Mar 31, 2025 | -146.94 Mn |
| Dec 31, 2024 | -104.35 Mn |
| Sep 30, 2024 | -140.48 Mn |
| Jun 30, 2024 | -66.27 Mn |
| Mar 31, 2024 | -142.80 Mn |
| Dec 31, 2023 | -9.26 Mn |
| Sep 30, 2023 | -147.41 Mn |
| Jun 30, 2023 | -85.29 Mn |
| Mar 31, 2023 | -124.32 Mn |
| Dec 31, 2022 | -52.43 Mn |
| Sep 30, 2022 | -46.99 Mn |
| Jun 30, 2022 | -105.14 Mn |
| Mar 31, 2022 | -65.17 Mn |
| Dec 31, 2021 | 224.61 Mn |
| Sep 30, 2021 | -82.47 Mn |