Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly Profit After Tax of -$92.5 million in Q1 2026, up 59.66% quarter-over-quarter from -$229.4 million in Q4 2025, and up 37.03% on a YoY basis from -$67.5 million in Q1 2025.
Ionis Pharmaceuticals (IONS) Profit After Tax (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Profit After Tax history runs 18 years deep, the most recent figure standing at -$92.5 million for Q1 2026.
- In Q1 2026, Profit After Tax rose 37.03% year-over-year to -$92.5 million; the TTM figure through Mar 2026 stood at -$327.0 million (up 28.61% YoY), while the FY2025 annual figure was -$381.4 million, up 15.97% from the prior year.
- Profit After Tax was -$92.5 million for Q1 2026 at Ionis Pharmaceuticals, up from -$229.4 million in the prior quarter.
- In the past five years, Profit After Tax ranged from a high of $123.6 million in Q2 2025 to a low of -$229.4 million in Q4 2025.
- Historically, Profit After Tax has averaged -$92.0 million across 5 years, with a median of -$104.3 million in 2024.
- The sharpest annual moves came in 2024 and 2025: Profit After Tax tumbled 1026.51% in 2024, then jumped 286.45% in 2025.
- A 5-year view of Profit After Tax shows it stood at -$52.4 million in 2022, then jumped by 82.33% to -$9.3 million in 2023, then sank by 1026.51% to -$104.3 million in 2024, then sank by 119.83% to -$229.4 million in 2025, then jumped by 59.66% to -$92.5 million in 2026.
- The last three Profit After Tax figures came in at -$92.5 million (Q1 2026), -$229.4 million (Q4 2025), and -$128.6 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | PAT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.94 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 30.90 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.63 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.46 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -753,254.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.03 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -56.74 Mn |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | -92.53 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -92.53 Mn |
| Dec 31, 2025 | -229.39 Mn |
| Sep 30, 2025 | -128.61 Mn |
| Jun 30, 2025 | 123.55 Mn |
| Mar 31, 2025 | -146.94 Mn |
| Dec 31, 2024 | -104.35 Mn |
| Sep 30, 2024 | -140.48 Mn |
| Jun 30, 2024 | -66.27 Mn |
| Mar 31, 2024 | -142.80 Mn |
| Dec 31, 2023 | -9.26 Mn |
| Sep 30, 2023 | -147.41 Mn |
| Jun 30, 2023 | -85.29 Mn |
| Mar 31, 2023 | -124.32 Mn |
| Dec 31, 2022 | -52.43 Mn |
| Sep 30, 2022 | -46.99 Mn |
| Jun 30, 2022 | -105.14 Mn |
| Mar 31, 2022 | -65.17 Mn |
| Dec 31, 2021 | 224.61 Mn |
| Sep 30, 2021 | -82.47 Mn |
| Jun 30, 2021 | -80.88 Mn |