Ionis Pharmaceuticals (IONS) Net Income (2009 - 2026)

Ionis Pharmaceuticals' (IONS) quarterly Net Income came in at -$92.5 million in Q1 2026, up 37.03% year-on-year from -$67.5 million in Q1 2025, and up 61.41% quarter-over-quarter from -$239.8 million in Q4 2025.

Ionis Pharmaceuticals (IONS) Net Income (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Net Income history runs 18 years deep, the most recent figure standing at -$92.5 million for Q1 2026.

  • On a quarterly basis, Net Income rose 37.03% year-over-year to -$92.5 million in Q1 2026; TTM through Mar 2026 was -$337.3 million, a 25.53% increase from a year earlier, with the FY2025 full-year figure at -$391.7 million, up 12.72% from the prior year.
  • Net Income grew to -$92.5 million in Q1 2026 per IONS's latest filing, from -$239.8 million in the prior quarter.
  • Across five years, Net Income topped out at $325.4 million in Q4 2023 and bottomed at -$239.8 million in Q4 2025.
  • The 5-year median for Net Income is -$99.3 million (2024), against an average of -$71.7 million.
  • Biggest YoY gain for Net Income was 965.43% in 2023; the steepest drop was 213.69% in 2023.
  • Year by year, Net Income stood at -$37.6 million in 2022, then jumped by 965.43% to $325.4 million in 2023, then sank by 130.51% to -$99.3 million in 2024, then slumped by 141.5% to -$239.8 million in 2025, then surged by 61.41% to -$92.5 million in 2026.
  • Per Business Quant, the three latest IONS Net Income figures stand at -$92.5 million (Q1 2026), -$239.8 million (Q4 2025), and -$128.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -37.09 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -14.46 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 227.36 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 498.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 Ionis Pharmaceuticals 9.35 Bn 7.43 Bn 243.11 Mn -92.53 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -92.53 Mn
Dec 31, 2025 -239.75 Mn
Sep 30, 2025 -128.61 Mn
Jun 30, 2025 123.55 Mn
Mar 31, 2025 -146.94 Mn
Dec 31, 2024 -99.28 Mn
Sep 30, 2024 -140.48 Mn
Jun 30, 2024 -66.27 Mn
Mar 31, 2024 -142.80 Mn
Dec 31, 2023 325.42 Mn
Sep 30, 2023 -147.41 Mn
Jun 30, 2023 -85.25 Mn
Mar 31, 2023 -124.34 Mn
Dec 31, 2022 -37.60 Mn
Sep 30, 2022 -46.99 Mn
Jun 30, 2022 -105.14 Mn
Mar 31, 2022 -65.17 Mn
Dec 31, 2021 254.53 Mn
Sep 30, 2021 -82.47 Mn
Jun 30, 2021 -80.88 Mn