Ionis Pharmaceuticals (IONS) Net Income (2009 - 2026)
Ionis Pharmaceuticals' (IONS) quarterly Net Income came in at -$92.5 million in Q1 2026, up 37.03% year-on-year from -$67.5 million in Q1 2025, and up 61.41% quarter-over-quarter from -$239.8 million in Q4 2025.
Ionis Pharmaceuticals (IONS) Net Income (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Net Income history runs 18 years deep, the most recent figure standing at -$92.5 million for Q1 2026.
- On a quarterly basis, Net Income rose 37.03% year-over-year to -$92.5 million in Q1 2026; TTM through Mar 2026 was -$337.3 million, a 25.53% increase from a year earlier, with the FY2025 full-year figure at -$391.7 million, up 12.72% from the prior year.
- Net Income grew to -$92.5 million in Q1 2026 per IONS's latest filing, from -$239.8 million in the prior quarter.
- Across five years, Net Income topped out at $325.4 million in Q4 2023 and bottomed at -$239.8 million in Q4 2025.
- The 5-year median for Net Income is -$99.3 million (2024), against an average of -$71.7 million.
- Biggest YoY gain for Net Income was 965.43% in 2023; the steepest drop was 213.69% in 2023.
- Year by year, Net Income stood at -$37.6 million in 2022, then jumped by 965.43% to $325.4 million in 2023, then sank by 130.51% to -$99.3 million in 2024, then slumped by 141.5% to -$239.8 million in 2025, then surged by 61.41% to -$92.5 million in 2026.
- Per Business Quant, the three latest IONS Net Income figures stand at -$92.5 million (Q1 2026), -$239.8 million (Q4 2025), and -$128.6 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Income (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -37.09 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -14.46 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 227.36 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.03 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 727.20 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -26.94 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 498.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -453.82 Mn |
| 10 | Ionis Pharmaceuticals | 9.35 Bn | 7.43 Bn | 243.11 Mn | -92.53 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -92.53 Mn |
| Dec 31, 2025 | -239.75 Mn |
| Sep 30, 2025 | -128.61 Mn |
| Jun 30, 2025 | 123.55 Mn |
| Mar 31, 2025 | -146.94 Mn |
| Dec 31, 2024 | -99.28 Mn |
| Sep 30, 2024 | -140.48 Mn |
| Jun 30, 2024 | -66.27 Mn |
| Mar 31, 2024 | -142.80 Mn |
| Dec 31, 2023 | 325.42 Mn |
| Sep 30, 2023 | -147.41 Mn |
| Jun 30, 2023 | -85.25 Mn |
| Mar 31, 2023 | -124.34 Mn |
| Dec 31, 2022 | -37.60 Mn |
| Sep 30, 2022 | -46.99 Mn |
| Jun 30, 2022 | -105.14 Mn |
| Mar 31, 2022 | -65.17 Mn |
| Dec 31, 2021 | 254.53 Mn |
| Sep 30, 2021 | -82.47 Mn |
| Jun 30, 2021 | -80.88 Mn |