Ionis Pharmaceuticals (IONS) EPS (Basic) (2009 - 2026)

Ionis Pharmaceuticals' (IONS) quarterly EPS (Basic) came in at -$0.56 in Q1 2026, up 39.37% year-on-year from -$0.4 in Q1 2025, and down 172.28% quarter-over-quarter from $0.78 in Q4 2025.

Ionis Pharmaceuticals (IONS) EPS (Basic) (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' EPS (Basic) history runs 18 years deep, the most recent figure standing at -$0.56 for Q1 2026.

  • On a quarterly basis, EPS (Basic) rose 39.37% year-over-year to -$0.56 in Q1 2026; TTM through Mar 2026 was $0.16, a 105.52% increase from a year earlier, with the FY2025 full-year figure at -$2.46, up 18.0% from the prior year.
  • EPS (Basic) declined to -$0.56 in Q1 2026 per IONS's latest filing, from $0.78 in the prior quarter.
  • Across five years, EPS (Basic) topped out at $2.27 in Q4 2023 and bottomed at -$1.03 in Q3 2023.
  • The 5-year median for EPS (Basic) is -$0.6 (2023), against an average of -$0.34.
  • Biggest YoY gain for EPS (Basic) was 957.32% in 2023; the steepest drop was 210.7% in 2023.
  • Year by year, EPS (Basic) stood at -$0.27 in 2022, then surged by 957.32% to $2.27 in 2023, then plunged by 129.22% to -$0.66 in 2024, then soared by 216.93% to $0.78 in 2025, then sank by 172.28% to -$0.56 in 2026.
  • Per Business Quant, the three latest IONS EPS (Basic) figures stand at -$0.56 (Q1 2026), $0.78 (Q4 2025), and -$0.8 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - 0.00
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 0.00
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 0.16
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 4.06
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 6.99
7 Belite Bio 61.40 Bn 61.40 Bn - 0.00
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 5.90
9 Revolution Medicines 37.37 Bn 37.37 Bn - -2.29
10 Ionis Pharmaceuticals 9.35 Bn 7.43 Bn 243.11 Mn -0.56

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.56
Dec 31, 2025 0.78
Sep 30, 2025 -0.80
Jun 30, 2025 0.78
Mar 31, 2025 -0.93
Dec 31, 2024 -0.66
Sep 30, 2024 -0.95
Jun 30, 2024 -0.45
Mar 31, 2024 -0.98
Dec 31, 2023 2.27
Sep 30, 2023 -1.03
Jun 30, 2023 -0.60
Mar 31, 2023 -0.87
Dec 31, 2022 -0.27
Sep 30, 2022 -0.33
Jun 30, 2022 -0.74
Mar 31, 2022 -0.46
Dec 31, 2021 1.80
Sep 30, 2021 -0.58
Jun 30, 2021 -0.57