Ionis Pharmaceuticals (IONS) EBT (2009 - 2026)
Ionis Pharmaceuticals' (IONS) quarterly EBT came in at -$92.3 million in Q1 2026, up 37.13% year-on-year from -$67.3 million in Q1 2025, and up 59.5% quarter-over-quarter from -$227.9 million in Q4 2025.
Ionis Pharmaceuticals (IONS) EBT (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' EBT history runs 18 years deep, the most recent figure standing at -$92.3 million for Q1 2026.
- On a quarterly basis, EBT rose 37.13% year-over-year to -$92.3 million in Q1 2026; TTM through Mar 2026 was -$325.1 million, a 30.06% increase from a year earlier, with the FY2025 full-year figure at -$379.6 million, up 17.61% from the prior year.
- EBT climbed to -$92.3 million in Q1 2026 per IONS's latest filing, from -$227.9 million in the prior quarter.
- Across five years, EBT topped out at $331.9 million in Q4 2023 and bottomed at -$227.9 million in Q4 2025.
- The 5-year median for EBT is -$102.9 million (2022), against an average of -$70.0 million.
- Biggest YoY gain for EBT was 848.79% in 2023; the steepest drop was 201.46% in 2023.
- Year by year, EBT stood at -$44.3 million in 2022, then soared by 848.79% to $331.9 million in 2023, then plunged by 132.44% to -$107.7 million in 2024, then slumped by 111.65% to -$227.9 million in 2025, then surged by 59.5% to -$92.3 million in 2026.
- Per Business Quant, the three latest IONS EBT figures stand at -$92.3 million (Q1 2026), -$227.9 million (Q4 2025), and -$128.4 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -36.97 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.31 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 259.22 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.25 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 831.20 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -26.94 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 438.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -453.82 Mn |
| 10 | Ionis Pharmaceuticals | 9.35 Bn | 7.43 Bn | 243.11 Mn | -92.31 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -92.31 Mn |
| Dec 31, 2025 | -227.92 Mn |
| Sep 30, 2025 | -128.39 Mn |
| Jun 30, 2025 | 123.53 Mn |
| Mar 31, 2025 | -146.82 Mn |
| Dec 31, 2024 | -107.68 Mn |
| Sep 30, 2024 | -144.10 Mn |
| Jun 30, 2024 | -66.20 Mn |
| Mar 31, 2024 | -142.73 Mn |
| Dec 31, 2023 | 331.94 Mn |
| Sep 30, 2023 | -140.81 Mn |
| Jun 30, 2023 | -77.45 Mn |
| Mar 31, 2023 | -112.94 Mn |
| Dec 31, 2022 | -44.33 Mn |
| Sep 30, 2022 | -46.71 Mn |
| Jun 30, 2022 | -102.88 Mn |
| Mar 31, 2022 | -64.07 Mn |
| Dec 31, 2021 | 254.88 Mn |
| Sep 30, 2021 | -83.77 Mn |
| Jun 30, 2021 | -80.55 Mn |