Ionis Pharmaceuticals (IONS) EBT (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly EBT of -$92.3 million in Q1 2026, up 59.78% quarter-over-quarter from -$229.5 million in Q4 2025, and up 37.13% on a YoY basis from -$67.3 million in Q1 2025.
Ionis Pharmaceuticals (IONS) EBT (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' EBT history runs 18 years deep, the most recent figure standing at -$92.3 million for Q1 2026.
- In Q1 2026, EBT rose 37.13% year-over-year to -$92.3 million; the TTM figure through Mar 2026 stood at -$326.7 million (up 29.72% YoY), while the FY2025 annual figure was -$381.2 million, up 17.26% from the prior year.
- EBT was -$92.3 million for Q1 2026 at Ionis Pharmaceuticals, up from -$229.5 million in the prior quarter.
- In the past five years, EBT ranged from a high of $123.5 million in Q2 2025 to a low of -$229.5 million in Q4 2025.
- Historically, EBT has averaged -$89.8 million across 5 years, with a median of -$102.9 million in 2022.
- The sharpest annual moves came in 2024 and 2025: EBT sank 3791.69% in 2024, then jumped 286.6% in 2025.
- A 5-year view of EBT shows it stood at -$44.8 million in 2022, then surged by 93.83% to -$2.8 million in 2023, then tumbled by 3791.69% to -$107.7 million in 2024, then slumped by 113.12% to -$229.5 million in 2025, then soared by 59.78% to -$92.3 million in 2026.
- The last three EBT figures came in at -$92.3 million (Q1 2026), -$229.5 million (Q4 2025), and -$128.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.94 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 19.60 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.18 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.31 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -1.50 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -56.48 Mn |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | -92.31 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -92.31 Mn |
| Dec 31, 2025 | -229.50 Mn |
| Sep 30, 2025 | -128.39 Mn |
| Jun 30, 2025 | 123.53 Mn |
| Mar 31, 2025 | -146.82 Mn |
| Dec 31, 2024 | -107.68 Mn |
| Sep 30, 2024 | -144.10 Mn |
| Jun 30, 2024 | -66.20 Mn |
| Mar 31, 2024 | -142.73 Mn |
| Dec 31, 2023 | -2.77 Mn |
| Sep 30, 2023 | -140.81 Mn |
| Jun 30, 2023 | -77.45 Mn |
| Mar 31, 2023 | -112.94 Mn |
| Dec 31, 2022 | -44.84 Mn |
| Sep 30, 2022 | -46.71 Mn |
| Jun 30, 2022 | -102.88 Mn |
| Mar 31, 2022 | -64.07 Mn |
| Dec 31, 2021 | 224.10 Mn |
| Sep 30, 2021 | -83.77 Mn |
| Jun 30, 2021 | -80.55 Mn |