Ionis Pharmaceuticals (IONS) EBT (2009 - 2026)
Ionis Pharmaceuticals (IONS) posted quarterly EBT of -$113.4 million for Q2 2026, down 191.78% year-over-year from $123.5 million in Q2 2025, and down 22.83% quarter-over-quarter from -$92.3 million in Q1 2026.
Ionis Pharmaceuticals (IONS) EBT (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' EBT history runs 18 years deep, the most recent figure standing at -$113.4 million for Q2 2026.
- In Q2 2026, EBT fell 191.78% year-over-year to -$113.4 million; the TTM figure through Jun 2026 stood at -$563.6 million (down 104.88% YoY), while the FY2025 annual figure was -$381.2 million, up 17.26% from the prior year.
- EBT for Q2 2026 stood at -$113.4 million, down from -$92.3 million in the prior quarter.
- The five-year high for EBT was $123.5 million in Q2 2025, with the low at -$229.5 million in Q4 2025.
- The 5-year median for EBT is -$105.3 million (2022), against an average of -$91.2 million.
- The sharpest annual moves came in 2024 and 2025: EBT sank 2968.77% in 2024, then soared 286.6% in 2025.
- Ionis Pharmaceuticals' EBT stood at -$44.8 million in 2022, then jumped by 92.17% to -$3.5 million in 2023, then tumbled by 2968.77% to -$107.7 million in 2024, then sank by 113.12% to -$229.5 million in 2025, then jumped by 50.6% to -$113.4 million in 2026.
- Business Quant data shows IONS's EBT at -$113.4 million in Q2 2026, -$92.3 million in Q1 2026, and -$229.5 million in Q4 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.39 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.53 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 541.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -644.37 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 312.46 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -2,828.29 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 81.49 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 177.81 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -11.37 Mn |
| 10 | Ionis Pharmaceuticals | 9.48 Bn | 7.43 Bn | 265.21 Mn | -113.38 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -113.38 Mn |
| Mar 31, 2026 | -92.31 Mn |
| Dec 31, 2025 | -229.50 Mn |
| Sep 30, 2025 | -128.39 Mn |
| Jun 30, 2025 | 123.53 Mn |
| Mar 31, 2025 | -146.82 Mn |
| Dec 31, 2024 | -107.68 Mn |
| Sep 30, 2024 | -144.10 Mn |
| Jun 30, 2024 | -66.20 Mn |
| Mar 31, 2024 | -142.73 Mn |
| Dec 31, 2023 | -3.51 Mn |
| Sep 30, 2023 | -140.81 Mn |
| Jun 30, 2023 | -77.45 Mn |
| Mar 31, 2023 | -112.94 Mn |
| Dec 31, 2022 | -44.84 Mn |
| Sep 30, 2022 | -46.71 Mn |
| Jun 30, 2022 | -102.88 Mn |
| Mar 31, 2022 | -64.07 Mn |
| Dec 31, 2021 | 224.10 Mn |
| Sep 30, 2021 | -83.77 Mn |