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Ionis Pharmaceuticals (IONS) EBITDA (2016 - 2025)

Historic EBITDA for Ionis Pharmaceuticals (IONS) over the last 17 years, with Q3 2025 value amounting to -$160.2 million.

  • Ionis Pharmaceuticals' EBITDA fell 775.35% to -$160.2 million in Q3 2025 from the same period last year, while for Sep 2025 it was -$278.0 million, marking a year-over-year increase of 2492.97%. This contributed to the annual value of -$475.1 million for FY2024, which is 3430.61% down from last year.
  • As of Q3 2025, Ionis Pharmaceuticals' EBITDA stood at -$160.2 million, which was down 775.35% from $139.8 million recorded in Q2 2025.
  • Ionis Pharmaceuticals' EBITDA's 5-year high stood at $220.6 million during Q4 2021, with a 5-year trough of -$208.0 million in Q4 2022.
  • Its 5-year average for EBITDA is -$75.6 million, with a median of -$90.2 million in 2023.
  • As far as peak fluctuations go, Ionis Pharmaceuticals' EBITDA soared by 107336.3% in 2021, and later tumbled by 171020.91% in 2024.
  • Over the past 5 years, Ionis Pharmaceuticals' EBITDA (Quarter) stood at $220.6 million in 2021, then plummeted by 194.3% to -$208.0 million in 2022, then surged by 97.06% to -$6.1 million in 2023, then tumbled by 1710.21% to -$110.8 million in 2024, then tumbled by 44.54% to -$160.2 million in 2025.
  • Its EBITDA was -$160.2 million in Q3 2025, compared to $139.8 million in Q2 2025 and -$146.9 million in Q1 2025.