Ionis Pharmaceuticals IONS
NASDAQ IONS
$44.27 -1.13 (-2.49%)
At close: Oct 21, 2026 · 4:00 PM EDT

Ionis Pharmaceuticals (IONS) EBITDA (2013 - 2026)

Updated

Ionis Pharmaceuticals (IONS) posted EBITDA of -$98.16 million for Q2 2026, compared with $142.68 million a year earlier.

Analysis

Ionis Pharmaceuticals (IONS) EBITDA (2013 - 2026) Analysis & Trends

For the trailing twelve months through Jun 30, 2026, EBITDA at Ionis Pharmaceuticals was -$579.49 million; for FY2025, it was -$369.24 million.

  • In prior years, Ionis Pharmaceuticals' EBITDA was -$463.13 million in FY2024, -$340.88 million in FY2023, -$393.45 million in FY2022 and -$12.35 million in FY2021.
  • Quarterly EBITDA has run from a low of -$210.56 million in Q4 2025 to a high of $225.04 million in Q4 2021 over five years.
  • According to Business Quant data, EBITDA for the three prior quarters was -$113.46 million (Q1 2026), -$210.56 million (Q4 2025) and -$157.31 million (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Eli Lilly 1,136.97 Bn 1,105.55 Bn 19.71 Bn 12.29 Bn
2 Johnson & Johnson 619.72 Bn 538.25 Bn 17.26 Bn 9.10 Bn
3 AbbVie 503.40 Bn 476.52 Bn 12.70 Bn 8.33 Bn
4 Merck 370.15 Bn 324.53 Bn 12.21 Bn 999.00 Mn
5 Novartis Ag 298.64 Bn 262.63 Bn 11.24 Bn -
6 Astrazeneca 261.07 Bn 234.76 Bn 12.86 Bn 5.09 Bn
7 Amgen 237.00 Bn 192.40 Bn 7.24 Bn 4.63 Bn
8 Gilead Sciences 191.24 Bn 165.43 Bn 6.22 Bn -9.70 Bn
9 Pfizer 170.31 Bn 116.96 Bn 10.94 Bn 5.89 Bn
10 Ionis Pharmaceuticals 7.33 Bn -1.56 Bn 265.21 Mn -96.36 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -96.36 Mn
Mar 31, 2026 -111.11 Mn
Dec 31, 2025 -208.59 Mn
Sep 30, 2025 -155.65 Mn
Jun 30, 2025 144.33 Mn
Mar 31, 2025 -142.41 Mn
Dec 31, 2024 -106.45 Mn
Sep 30, 2024 -144.00 Mn
Jun 30, 2024 -61.33 Mn
Mar 31, 2024 -144.66 Mn
Dec 31, 2023 -1.26 Mn
Sep 30, 2023 -138.38 Mn
Jun 30, 2023 -85.46 Mn
Mar 31, 2023 -109.45 Mn
Dec 31, 2022 -203.04 Mn
Sep 30, 2022 -53.38 Mn
Jun 30, 2022 -79.78 Mn
Mar 31, 2022 -51.87 Mn
Dec 31, 2021 226.41 Mn
Sep 30, 2021 -80.14 Mn
API Access

Ionis Pharmaceuticals EBITDA API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=ebitda&ticker=IONS&period=max&api_key=YOUR_API_KEY