Immatics (IMTX) Operating Income (2019 - 2025)

Immatics recorded quarterly Operating Income of -$45.3 million in Q4 2025, up 29.14% quarter-over-quarter from -$63.9 million in Q3 2025, and down 4790.35% year-over-year from $964941.6 in Q4 2024.

Immatics' Operating Income history runs 7 years deep, the most recent figure standing at -$45.3 million for Q4 2025.

  • In Q4 2025, Operating Income fell 4790.35% year-over-year to -$45.3 million; the TTM figure through Dec 2025 stood at -$206.5 million (down 395.03% YoY), while the FY2025 annual figure was -$205.6 million, down 398.36% from the prior year.
  • Operating Income came in at -$45.3 million for Q4 2025 at Immatics, up from -$63.9 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $76.9 million in Q1 2022 to a low of -$63.9 million in Q3 2025.
  • A 5-year average of -$21.2 million and a median of -$27.6 million in 2021 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income jumped 367.34% in 2022 and sank 65048.52% in 2023, its largest moves.
  • Immatics' Operating Income stood at -$18.4 million in 2021, then surged by 100.25% to $45911.1 in 2022, then tumbled by 65048.52% to -$29.8 million in 2023, then jumped by 103.24% to $964941.6 in 2024, then plunged by 4790.35% to -$45.3 million in 2025.
  • According to Business Quant data, Operating Income over the past three periods registered -$45.3 million, -$63.9 million, and -$60.1 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.97 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 268.64 Mn
10 Immatics 1.80 Bn 1.80 Bn - -45.26 Mn

Historic Data

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DateValue
Dec 31, 2025 -45.26 Mn
Sep 30, 2025 -63.87 Mn
Jun 30, 2025 -60.14 Mn
Mar 31, 2025 -37.21 Mn
Dec 31, 2024 964,941.65
Sep 30, 2024 564,484.82
Jun 30, 2024 -28.61 Mn
Mar 31, 2024 -14.63 Mn
Dec 31, 2023 -29.82 Mn
Sep 30, 2023 -36.21 Mn
Jun 30, 2023 -15.59 Mn
Mar 31, 2023 -28.37 Mn
Dec 31, 2022 45,911.13
Sep 30, 2022 -22.11 Mn
Jun 30, 2022 -17.77 Mn
Mar 31, 2022 76.87 Mn
Dec 31, 2021 -18.37 Mn
Sep 30, 2021 -27.12 Mn
Jun 30, 2021 -28.18 Mn
Mar 31, 2021 -28.75 Mn
Dec 31, 2020 -23.88 Mn
Sep 30, 2020 -21.96 Mn
Jun 30, 2020 -21.59 Mn
Mar 31, 2020 -12.45 Mn
Dec 31, 2019 -13.59 Mn
Sep 30, 2019 -8.63 Mn
Jun 30, 2019 -7.12 Mn