Immunome (IMNM) Operating Income (2019 - 2026)
Immunome (IMNM) posted Operating Income of -$59.3 million for Q1 2026, up 18.57% on a QoQ basis from -$72.9 million in Q4 2025, and down 32.92% year-over-year from -$88.5 million in Q1 2025.
Immunome (IMNM) Operating Income (2019 - 2026) Analysis & Trends
Immunome's Operating Income history runs 8 years deep, the most recent figure standing at -$59.3 million for Q1 2026.
- Quarterly Operating Income fell 32.92% year-over-year to -$59.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$238.8 million (down 9.48% YoY) and the FY2025 annual result came in at -$224.1 million, up 26.71% from the prior year.
- Operating Income was -$59.3 million for Q1 2026 at Immunome, up from -$72.9 million in the prior quarter.
- Across five years, Operating Income topped out at -$4.5 million in Q1 2023 and bottomed at -$132.3 million in Q1 2024.
- A 5-year average of -$43.3 million and a median of -$44.6 million in 2025 frame the typical range for Operating Income.
- Annual changes were most pronounced in 2024 — Operating Income plunged 2859.05% — and 2025, when it soared 66.26%.
- Immunome's Operating Income stood at -$7.8 million in 2022, then slumped by 1115.53% to -$94.7 million in 2023, then grew by 12.34% to -$83.0 million in 2024, then grew by 12.18% to -$72.9 million in 2025, then increased by 18.57% to -$59.3 million in 2026.
- Business Quant data shows IMNM's Operating Income at -$59.3 million in Q1 2026, -$72.9 million in Q4 2025, and -$60.1 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Immunome | 2.49 Bn | 1.91 Bn | - | -59.33 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -59.33 Mn |
| Dec 31, 2025 | -72.86 Mn |
| Sep 30, 2025 | -60.14 Mn |
| Jun 30, 2025 | -46.48 Mn |
| Mar 31, 2025 | -44.64 Mn |
| Dec 31, 2024 | -82.97 Mn |
| Sep 30, 2024 | -50.52 Mn |
| Jun 30, 2024 | -40.01 Mn |
| Mar 31, 2024 | -132.30 Mn |
| Dec 31, 2023 | -94.65 Mn |
| Sep 30, 2023 | -4.63 Mn |
| Jun 30, 2023 | -5.77 Mn |
| Mar 31, 2023 | -4.47 Mn |
| Dec 31, 2022 | -7.79 Mn |
| Sep 30, 2022 | -8.53 Mn |
| Jun 30, 2022 | -8.93 Mn |
| Mar 31, 2022 | -11.65 Mn |
| Dec 31, 2021 | -7.84 Mn |
| Sep 30, 2021 | -7.72 Mn |
| Jun 30, 2021 | -5.74 Mn |