Humacyte (HUMA) EBITDA (2020 - 2026)
Humacyte (HUMA) reported EBITDA of -$28.9 million for Q1 2026, down 173.93% year-over-year from $39.1 million in Q1 2025, and up 6.16% quarter-over-quarter from -$30.8 million in Q4 2025.
Humacyte (HUMA) EBITDA (2020 - 2026) Analysis & Trends
Humacyte (HUMA) has 7 years of EBITDA data on file, last reported at -$28.9 million in Q1 2026.
- EBITDA for Q1 2026 came in at -$28.9 million, down 173.93% year-over-year; the trailing twelve-month figure through Mar 2026 was -$114.9 million (down 47.99% YoY), and the FY2025 annual result was -$108.1 million, up 27.28% from the prior year.
- EBITDA improved to -$28.9 million in Q1 2026 per HUMA's latest filing, from -$30.8 million in the prior quarter.
- Over five years, EBITDA peaked at $39.1 million in Q1 2025 and troughed at -$56.7 million in Q2 2024.
- A 5-year average of -$20.4 million and a median of -$25.3 million in 2022 frame the typical range for EBITDA.
- The sharpest annual moves came in 2022 and 2023: EBITDA jumped 314.37% in 2022, then sank 574.89% in 2023.
- A 5-year view of EBITDA shows it stood at -$3.7 million in 2022, then slumped by 574.89% to -$25.1 million in 2023, then climbed by 16.59% to -$20.9 million in 2024, then tumbled by 47.26% to -$30.8 million in 2025, then gained by 6.16% to -$28.9 million in 2026.
- Business Quant data shows HUMA's EBITDA at -$28.9 million in Q1 2026, -$30.8 million in Q4 2025, and -$17.5 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | - |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -65.83 Mn |
| 10 | Humacyte | 267.09 Mn | 218.55 Mn | -1.54 Mn | -28.94 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -28.94 Mn |
| Dec 31, 2025 | -30.84 Mn |
| Sep 30, 2025 | -17.51 Mn |
| Jun 30, 2025 | -37.66 Mn |
| Mar 31, 2025 | 39.14 Mn |
| Dec 31, 2024 | -20.94 Mn |
| Sep 30, 2024 | -39.20 Mn |
| Jun 30, 2024 | -56.66 Mn |
| Mar 31, 2024 | -31.90 Mn |
| Dec 31, 2023 | -25.11 Mn |
| Sep 30, 2023 | -26.00 Mn |
| Jun 30, 2023 | -22.71 Mn |
| Mar 31, 2023 | -36.97 Mn |
| Dec 31, 2022 | -3.72 Mn |
| Sep 30, 2022 | -25.28 Mn |
| Jun 30, 2022 | 36.87 Mn |
| Mar 31, 2022 | -19.83 Mn |
| Dec 31, 2021 | 42.59 Mn |
| Sep 30, 2021 | -31.56 Mn |
| Jun 30, 2021 | -17.20 Mn |