Growth Metrics

Harmony Biosciences Holdings (HRMY) Operating Income (2019 - 2026)

Harmony Biosciences Holdings recorded quarterly Operating Income of $8.3 million in Q1 2026, up 106.68% quarter-over-quarter from -$124.7 million in Q4 2025, and down 85.18% year-over-year from $56.2 million in Q1 2025.

Harmony Biosciences Holdings' Operating Income history runs 8 years deep, the most recent figure standing at $8.3 million for Q1 2026.

  • In Q1 2026, Operating Income fell 85.18% year-over-year to $8.3 million; the TTM figure through Mar 2026 stood at -$2.7 million (down 101.41% YoY), while the FY2025 annual figure was $45.2 million, down 76.33% from the prior year.
  • Operating Income came in at $8.3 million for Q1 2026 at Harmony Biosciences Holdings, up from -$124.7 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $65.5 million in Q3 2025 to a low of -$124.7 million in Q4 2025.
  • A 5-year average of $32.7 million and a median of $46.9 million in 2023 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income surged 442.05% in 2023 and sank 323.86% in 2025, its largest moves.
  • Harmony Biosciences Holdings' Operating Income stood at $47.6 million in 2022, then dropped by 15.58% to $40.2 million in 2023, then jumped by 38.64% to $55.7 million in 2024, then tumbled by 323.86% to -$124.7 million in 2025, then jumped by 106.68% to $8.3 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered $8.3 million, -$124.7 million, and $65.5 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.97 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 268.64 Mn
10 Harmony Biosciences Holdings 1.83 Bn 1.19 Bn 170.88 Mn 8.33 Mn

Historic Data

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DateValue
Mar 31, 2026 8.33 Mn
Dec 31, 2025 -124.75 Mn
Sep 30, 2025 65.49 Mn
Jun 30, 2025 48.18 Mn
Mar 31, 2025 56.25 Mn
Dec 31, 2024 55.73 Mn
Sep 30, 2024 61.71 Mn
Jun 30, 2024 21.36 Mn
Mar 31, 2024 52.03 Mn
Dec 31, 2023 40.20 Mn
Sep 30, 2023 64.51 Mn
Jun 30, 2023 46.90 Mn
Mar 31, 2023 40.42 Mn
Dec 31, 2022 47.61 Mn
Sep 30, 2022 11.90 Mn
Jun 30, 2022 33.12 Mn
Mar 31, 2022 27.56 Mn
Dec 31, 2021 28.63 Mn
Sep 30, 2021 21.05 Mn
Jun 30, 2021 23.31 Mn
Mar 31, 2021 14.53 Mn
Dec 31, 2020 7.76 Mn
Sep 30, 2020 10.38 Mn
Jun 30, 2020 7.31 Mn
Mar 31, 2020 -9.61 Mn
Dec 31, 2019 -33.69 Mn
Sep 30, 2019 -29.80 Mn