Fractyl Health (GUTS) Operating Expenses (2023 - 2026)
Fractyl Health's (GUTS) quarterly Operating Expenses came in at $20.8 million in Q1 2026, down 15.91% YoY from $24.8 million in Q1 2025, and down 10.58% on a QoQ basis from $23.3 million in Q4 2025.
Fractyl Health (GUTS) Operating Expenses (2023 - 2026) Analysis & Trends
Fractyl Health (GUTS) has 4 years of Operating Expenses data on file, last reported at $20.8 million in Q1 2026.
- Quarterly Operating Expenses fell 15.91% year-over-year to $20.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $92.9 million (down 4.03% YoY) and the FY2025 annual result came in at $96.8 million, up 3.46% from the prior year.
- Operating Expenses fell to $20.8 million in Q1 2026, from $23.3 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $26.1 million in Q2 2025 to a low of $11.9 million in Q2 2023.
- A 4-year average of $20.2 million and a median of $22.7 million in 2025 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2024 — Operating Expenses soared 94.16% — and 2026, when it fell 15.91%.
- Tracing GUTS's Operating Expenses over 4 years: stood at $13.0 million in 2023, then soared by 94.16% to $25.2 million in 2024, then declined by 7.65% to $23.3 million in 2025, then declined by 10.58% to $20.8 million in 2026.
- The last three Operating Expenses figures came in at $20.8 million (Q1 2026), $23.3 million (Q4 2025), and $22.7 million (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 2.89 Bn |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | 960.00 Mn |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 1.21 Bn |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 1.06 Bn |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | 427.03 Mn |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 541.02 Mn |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | -784.57 Mn |
| 10 | Fractyl Health | 109.12 Mn | 109.12 Mn | - | 19.10 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 19.10 Mn |
| Mar 31, 2026 | 20.82 Mn |
| Dec 31, 2025 | 23.28 Mn |
| Sep 30, 2025 | 22.69 Mn |
| Jun 30, 2025 | 26.08 Mn |
| Mar 31, 2025 | 24.76 Mn |
| Dec 31, 2024 | 25.21 Mn |
| Sep 30, 2024 | 23.80 Mn |
| Jun 30, 2024 | 23.00 Mn |
| Mar 31, 2024 | 21.56 Mn |
| Dec 31, 2023 | 12.99 Mn |
| Sep 30, 2023 | 13.88 Mn |
| Jun 30, 2023 | 11.90 Mn |
| Mar 31, 2023 | 12.11 Mn |