Fractyl Health (GUTS) Operating Expenses (2023 - 2026)

Fractyl Health (GUTS) reported Operating Expenses of $20.8 million for Q1 2026, down 15.91% year-on-year from $24.8 million in Q1 2025, and down 10.58% quarter-over-quarter from $23.3 million in Q4 2025.

Fractyl Health (GUTS) has 4 years of Operating Expenses data on file, last reported at $20.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses fell 15.91% year-over-year to $20.8 million; the trailing twelve-month figure through Mar 2026 stood at $92.9 million (down 4.03% YoY), and the FY2025 full-year result was $96.8 million, up 3.46% from the prior year.
  • Operating Expenses for Q1 2026 stood at $20.8 million, down from $23.3 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $26.1 million in Q2 2025 and bottomed at $11.9 million in Q2 2023.
  • A 4-year average of $20.2 million and a median of $22.7 million in 2025 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses soared 94.16% in 2024 and fell 15.91% in 2026, its largest moves.
  • Tracing GUTS's Operating Expenses over 4 years: stood at $13.0 million in 2023, then soared by 94.16% to $25.2 million in 2024, then decreased by 7.65% to $23.3 million in 2025, then decreased by 10.58% to $20.8 million in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $20.8 million, $23.3 million, and $22.7 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 1,638,563.89 Bn 1,638,563.89 Bn - 2.97 Mn
2 Alterity Therapeutics 767,934.24 Bn 767,934.20 Bn - 4.33 Mn
3 Legend Biotech 2,937.00 Bn 2,936.10 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 2,169.69 Bn 2,169.69 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 110.41 Bn 103.16 Bn 2.59 Bn 1.85 Bn
7 Regeneron Pharmaceuticals 66.44 Bn 57.69 Bn 3.31 Bn 2.96 Bn
8 Evaxion A 65.44 Bn 65.42 Bn - -3.82 Mn
9 Alnylam Pharmaceuticals 39.53 Bn 36.52 Bn 959.66 Mn 898.54 Mn
10 Fractyl Health 19.24 Mn 19.24 Mn - 20.82 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 20.82 Mn
Dec 31, 2025 23.28 Mn
Sep 30, 2025 22.69 Mn
Jun 30, 2025 26.08 Mn
Mar 31, 2025 24.76 Mn
Dec 31, 2024 25.21 Mn
Sep 30, 2024 23.80 Mn
Jun 30, 2024 23.00 Mn
Mar 31, 2024 21.56 Mn
Dec 31, 2023 12.99 Mn
Sep 30, 2023 13.88 Mn
Jun 30, 2023 11.90 Mn
Mar 31, 2023 12.11 Mn