GH Research (GHRS) Return on Capital Employed (2021 - 2025)

GH Research (GHRS) recorded quarterly Return on Capital Employed of 21.17% in Q4 2025, down 10.56% quarter-over-quarter from 19.15% in Q3 2025, and up 602.0% on a YoY basis from 3.02% in Q4 2024.

GH Research (GHRS) Return on Capital Employed (2021 - 2025) Analysis & Trends

GH Research's Return on Capital Employed history runs 5 years deep, the most recent figure standing at 21.17% for Q4 2025.

  • In Q4 2025, Return on Capital Employed rose 602.0% year-over-year to 21.17%; the TTM figure through Dec 2025 stood at 21.17% (up 602.0% YoY), while the FY2025 annual figure was 26.41%, down 105.0% from the prior year.
  • Return on Capital Employed was 21.17% for Q4 2025 at GH Research, down from 19.15% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 5.33% in Q4 2021 to a low of 27.2% in Q4 2024.
  • Historically, Return on Capital Employed has averaged 16.65% across 5 years, with a median of 17.27% in 2025.
  • The sharpest annual moves came in 2024 and 2025: Return on Capital Employed tumbled 869 bps in 2024, then surged 602 bps in 2025.
  • A 5-year view of Return on Capital Employed shows it stood at 5.33% in 2021, then sank by 127 bps to 12.09% in 2022, then sank by 53 bps to 18.51% in 2023, then slumped by 47 bps to 27.2% in 2024, then climbed by 22 bps to 21.17% in 2025.
  • The last three Return on Capital Employed figures came in at 21.17% (Q4 2025), 19.15% (Q3 2025), and 17.27% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 GH Research 10.10 Bn 10.00 Bn - -21.17%

Historic Data

Download Data
DateValue
Dec 31, 2025 -21.17%
Sep 30, 2025 -19.15%
Jun 30, 2025 -17.27%
Mar 31, 2025 -21.07%
Dec 31, 2024 -27.20%
Sep 30, 2024 -25.08%
Jun 30, 2024 -22.31%
Mar 31, 2024 -19.72%
Dec 31, 2023 -18.51%
Sep 30, 2023 -17.04%
Jun 30, 2023 -15.17%
Mar 31, 2023 -13.45%
Dec 31, 2022 -12.09%
Sep 30, 2022 -10.78%
Jun 30, 2022 -9.76%
Mar 31, 2022 -7.94%
Dec 31, 2021 -5.33%