GH Research (GHRS) Return on Capital Employed (2021 - 2026)

GH Research (GHRS) posted quarterly Return on Capital Employed of 21.17% for Q4 2025, up 602.0% year-over-year from 3.02% in Q4 2024, and down 10.56% quarter-over-quarter from 19.15% in Q3 2025.

GH Research (GHRS) Return on Capital Employed (2021 - 2026) Analysis & Trends

GH Research's Return on Capital Employed history runs 5 years deep, the most recent figure standing at 21.17% for Q4 2025.

  • In Q4 2025, Return on Capital Employed rose 602.0% year-over-year to 21.17%; the TTM figure through Dec 2025 stood at 21.17% (up 602.0% YoY), while the FY2025 annual figure was 26.41%, down 105.0% from the prior year.
  • Return on Capital Employed for Q4 2025 stood at 21.17%, down from 19.15% in the prior quarter.
  • The five-year high for Return on Capital Employed was 5.33% in Q4 2021, with the low at 27.2% in Q4 2024.
  • The 5-year median for Return on Capital Employed is 17.27% (2025), against an average of 16.65%.
  • The sharpest annual moves came in 2024 and 2025: Return on Capital Employed slumped 869 bps in 2024, then jumped 602 bps in 2025.
  • GH Research's Return on Capital Employed stood at 5.33% in 2021, then plunged by 127 bps to 12.09% in 2022, then plunged by 53 bps to 18.51% in 2023, then sank by 47 bps to 27.2% in 2024, then advanced by 22 bps to 21.17% in 2025.
  • Business Quant data shows GHRS's Return on Capital Employed at 21.17% in Q4 2025, 19.15% in Q3 2025, and 17.27% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 10.74%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -55.45%
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -0.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 7.88%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 26.09%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -50.93%
10 GH Research 2.02 Bn 1.68 Bn - -21.25%

Historic Data

Download Data
DateValue
Jun 30, 2026 -21.25%
Dec 31, 2025 -21.17%
Sep 30, 2025 -19.15%
Jun 30, 2025 -17.27%
Mar 31, 2025 -21.07%
Dec 31, 2024 -27.20%
Sep 30, 2024 -25.08%
Jun 30, 2024 -22.31%
Mar 31, 2024 -19.72%
Dec 31, 2023 -18.51%
Sep 30, 2023 -17.04%
Jun 30, 2023 -15.17%
Mar 31, 2023 -13.45%
Dec 31, 2022 -12.09%
Sep 30, 2022 -10.78%
Jun 30, 2022 -9.76%
Mar 31, 2022 -7.94%
Dec 31, 2021 -5.33%