GH Research (GHRS) Return on Capital Employed (2021 - 2025)

GH Research's (GHRS) quarterly Return on Capital Employed came in at 21.17% in Q4 2025, up 602.0% year-on-year from 3.02% in Q4 2024, and down 10.56% quarter-over-quarter from 19.15% in Q3 2025.

GH Research (GHRS) Return on Capital Employed (2021 - 2025) Analysis & Trends

GH Research's Return on Capital Employed history runs 5 years deep, the most recent figure standing at 21.17% for Q4 2025.

  • On a quarterly basis, Return on Capital Employed rose 602.0% year-over-year to 21.17% in Q4 2025; TTM through Dec 2025 was 21.17%, a 602.0% increase from a year earlier, with the FY2025 full-year figure at 26.41%, down 105.0% from the prior year.
  • Return on Capital Employed retreated to 21.17% in Q4 2025 per GHRS's latest filing, from 19.15% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 5.33% in Q4 2021 and bottomed at 27.2% in Q4 2024.
  • The 5-year median for Return on Capital Employed is 17.27% (2025), against an average of 16.65%.
  • Across the five-year window, Return on Capital Employed tumbled 869 bps in 2024 and jumped 602 bps in 2025, its largest moves.
  • Year by year, Return on Capital Employed stood at 5.33% in 2021, then tumbled by 127 bps to 12.09% in 2022, then tumbled by 53 bps to 18.51% in 2023, then plunged by 47 bps to 27.2% in 2024, then climbed by 22 bps to 21.17% in 2025.
  • Per Business Quant, the three latest GHRS Return on Capital Employed figures stand at 21.17% (Q4 2025), 19.15% (Q3 2025), and 17.27% (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 GH Research 1.69 Bn 1.69 Bn - -21.17%

Historic Data

Download Data
DateValue
Dec 31, 2025 -21.17%
Sep 30, 2025 -19.15%
Jun 30, 2025 -17.27%
Mar 31, 2025 -21.07%
Dec 31, 2024 -27.20%
Sep 30, 2024 -25.08%
Jun 30, 2024 -22.31%
Mar 31, 2024 -19.72%
Dec 31, 2023 -18.51%
Sep 30, 2023 -17.04%
Jun 30, 2023 -15.17%
Mar 31, 2023 -13.45%
Dec 31, 2022 -12.09%
Sep 30, 2022 -10.78%
Jun 30, 2022 -9.76%
Mar 31, 2022 -7.94%
Dec 31, 2021 -5.33%