Fulcrum Therapeutics (FULC) Operating Income (2018 - 2026)
Fulcrum Therapeutics (FULC) posted quarterly Operating Income of -$29.3 million for Q2 2026, down 47.92% year-over-year from -$56.3 million in Q2 2025, and down 32.11% quarter-over-quarter from -$22.2 million in Q1 2026.
Analysis
Fulcrum Therapeutics (FULC) Operating Income (2018 - 2026) Analysis & Trends
Fulcrum Therapeutics (FULC) has reported Operating Income for 9 consecutive years, with -$29.3 million the latest figure, recorded in Q2 2026.
- In Q2 2026, Operating Income fell 47.92% year-over-year to -$29.3 million; the TTM figure through Jun 2026 stood at -$96.0 million (down 13.3% YoY), while the FY2025 annual figure was -$84.8 million, down 287.13% from the prior year.
- Operating Income slipped to -$29.3 million in Q2 2026 per FULC's latest filing, from -$22.2 million in the prior quarter.
- Across five years, Operating Income topped out at $52.5 million in Q2 2024 and bottomed at -$34.2 million in Q2 2022.
- Historically, Operating Income has averaged -$21.2 million across 5 years, with a median of -$25.6 million in 2022.
- Annual changes were most pronounced in 2024 — Operating Income jumped 292.33% — and 2025, when it tumbled 137.75%.
- Fulcrum Therapeutics' Operating Income stood at -$28.0 million in 2022, then slipped by 0.07% to -$28.0 million in 2023, then jumped by 30.59% to -$19.4 million in 2024, then retreated by 16.8% to -$22.7 million in 2025, then declined by 29.16% to -$29.3 million in 2026.
- Business Quant data shows FULC's Operating Income at -$29.3 million in Q2 2026, -$22.2 million in Q1 2026, and -$22.7 million in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 493.00 Mn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -815.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -505.13 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 325.05 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 133.12 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Fulcrum Therapeutics | 293.24 Mn | 293.24 Mn | - | -29.31 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -29.31 Mn |
| Mar 31, 2026 | -22.19 Mn |
| Dec 31, 2025 | -22.69 Mn |
| Sep 30, 2025 | -21.86 Mn |
| Jun 30, 2025 | -19.82 Mn |
| Mar 31, 2025 | -20.40 Mn |
| Dec 31, 2024 | -19.43 Mn |
| Sep 30, 2024 | -25.13 Mn |
| Jun 30, 2024 | 52.49 Mn |
| Mar 31, 2024 | -29.83 Mn |
| Dec 31, 2023 | -27.99 Mn |
| Sep 30, 2023 | -27.44 Mn |
| Jun 30, 2023 | -27.29 Mn |
| Mar 31, 2023 | -27.94 Mn |
| Dec 31, 2022 | -27.97 Mn |
| Sep 30, 2022 | -24.36 Mn |
| Jun 30, 2022 | -34.24 Mn |
| Mar 31, 2022 | -26.00 Mn |
| Dec 31, 2021 | -23.56 Mn |
| Sep 30, 2021 | -20.77 Mn |