Fulcrum Therapeutics (FULC) EBT (2018 - 2026)

Fulcrum Therapeutics' (FULC) quarterly EBT came in at -$50.0 million in Q1 2026, down 69.8% year-on-year from -$165.5 million in Q1 2025, and up 40.62% on a QoQ basis from -$84.2 million in Q4 2025.

Fulcrum Therapeutics (FULC) EBT (2018 - 2026) Analysis & Trends

Fulcrum Therapeutics (FULC) has 9 years of EBT data on file, last reported at -$50.0 million in Q1 2026.

  • On a quarterly basis, EBT fell 69.8% year-over-year to -$50.0 million in Q1 2026; TTM through Mar 2026 was -$241.1 million, a 179.3% decrease from a year earlier, with the FY2025 full-year figure at -$161.2 million, down 119.71% from the prior year.
  • EBT for Q1 2026 stood at -$50.0 million, up from -$84.2 million in the prior quarter.
  • Over the last five years, EBT for FULC reached as high as $40.2 million in Q2 2024 and fell as low as -$192.5 million in Q4 2022.
  • Historically, EBT has averaged -$52.1 million across 5 years, with a median of -$42.0 million in 2025.
  • Across the five-year window, EBT sank 310.77% in 2022 and soared 231.2% in 2024, its largest moves.
  • Year by year, EBT stood at -$192.5 million in 2022, then surged by 77.6% to -$43.1 million in 2023, then tumbled by 65.71% to -$71.4 million in 2024, then declined by 17.81% to -$84.2 million in 2025, then jumped by 40.62% to -$50.0 million in 2026.
  • Per Business Quant data, the three most recent EBT figures were -$50.0 million in Q1 2026, -$84.2 million in Q4 2025, and -$65.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.97 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.31 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 259.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 438.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 Fulcrum Therapeutics 285.43 Mn 285.43 Mn - -49.97 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -49.97 Mn
Dec 31, 2025 -84.15 Mn
Sep 30, 2025 -64.99 Mn
Jun 30, 2025 -41.97 Mn
Mar 31, 2025 -29.43 Mn
Dec 31, 2024 -71.43 Mn
Sep 30, 2024 -25.68 Mn
Jun 30, 2024 40.22 Mn
Mar 31, 2024 -65.24 Mn
Dec 31, 2023 -43.11 Mn
Sep 30, 2023 -40.26 Mn
Jun 30, 2023 -30.65 Mn
Mar 31, 2023 -30.52 Mn
Dec 31, 2022 -192.46 Mn
Sep 30, 2022 -27.08 Mn
Jun 30, 2022 -35.44 Mn
Mar 31, 2022 -94.00 Mn
Dec 31, 2021 -50.95 Mn
Sep 30, 2021 -96.47 Mn
Jun 30, 2021 -37.99 Mn