4D Molecular Therapeutics (FDMT) Operating Income (2020 - 2026)

4D Molecular Therapeutics' (FDMT) quarterly Operating Income came in at -$73.6 million in Q1 2026, down 37.3% year-on-year from -$117.4 million in Q1 2025, and down 600.31% on a QoQ basis from $14.7 million in Q4 2025.

4D Molecular Therapeutics (FDMT) Operating Income (2020 - 2026) Analysis & Trends

4D Molecular Therapeutics (FDMT) has 7 years of Operating Income data on file, last reported at -$73.6 million in Q1 2026.

  • On a quarterly basis, Operating Income fell 37.3% year-over-year to -$73.6 million in Q1 2026; TTM through Mar 2026 was -$179.5 million, a 11.7% increase from a year earlier, with the FY2025 full-year figure at -$159.5 million, up 15.06% from the prior year.
  • Operating Income for Q1 2026 stood at -$73.6 million, down from $14.7 million in the prior quarter.
  • Over the last five years, Operating Income for FDMT reached as high as $14.7 million in Q4 2025 and fell as low as -$73.6 million in Q1 2026.
  • Historically, Operating Income has averaged -$37.9 million across 5 years, with a median of -$36.7 million in 2023.
  • Across the five-year window, Operating Income tumbled 274.22% in 2022 and soared 126.22% in 2025, its largest moves.
  • Year by year, Operating Income stood at -$28.7 million in 2022, then retreated by 27.62% to -$36.7 million in 2023, then tumbled by 53.11% to -$56.1 million in 2024, then surged by 126.22% to $14.7 million in 2025, then plunged by 600.31% to -$73.6 million in 2026.
  • Per Business Quant data, the three most recent Operating Income figures were -$73.6 million in Q1 2026, $14.7 million in Q4 2025, and -$61.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 4D Molecular Therapeutics 691.54 Mn 300.64 Mn - -73.62 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -73.62 Mn
Dec 31, 2025 14.72 Mn
Sep 30, 2025 -61.19 Mn
Jun 30, 2025 -59.46 Mn
Mar 31, 2025 -53.62 Mn
Dec 31, 2024 -56.12 Mn
Sep 30, 2024 -51.13 Mn
Jun 30, 2024 -42.46 Mn
Mar 31, 2024 -38.14 Mn
Dec 31, 2023 -36.65 Mn
Sep 30, 2023 -13.97 Mn
Jun 30, 2023 -32.14 Mn
Mar 31, 2023 -30.11 Mn
Dec 31, 2022 -28.72 Mn
Sep 30, 2022 -26.50 Mn
Jun 30, 2022 -28.43 Mn
Mar 31, 2022 -26.39 Mn
Dec 31, 2021 -24.76 Mn
Sep 30, 2021 -22.66 Mn
Jun 30, 2021 -7.60 Mn