Ensysce Biosciences (ENSC) Return on Equity [ROE] (2018 - 2025)
Ensysce Biosciences' Return on Equity [ROE] came in at -514.69% for Q3 2025, down 317.97 percentage points from -196.72% a year earlier and down 286.99 percentage points from the prior quarter.
Powered by 
Analysis
Ensysce Biosciences (ENSC) Return on Equity [ROE] (2018 - 2025) Analysis & Trends
For FY2024, Ensysce Biosciences' Return on Equity [ROE] was -585.41%.
- The Q3 2025 figure represents the lowest quarterly Return on Equity [ROE] since Q1 2024.
- Year-over-year, Return on Equity [ROE] increased in five of the last six quarters, with an average year-over-year change of +916.60 percentage points.
- Business Quant data shows ENSC's Return on Equity [ROE] at -227.71% (Q2 2025), -223.46% (Q1 2025) and -160.39% (Q4 2024) in the three quarters before Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Ensysce Biosciences | 1.07 Mn | -10.50 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2025 | -514.69% |
| Jun 30, 2025 | -227.71% |
| Mar 31, 2025 | -223.46% |
| Dec 31, 2024 | -160.39% |
| Sep 30, 2024 | -196.72% |
| Jun 30, 2024 | -460.39% |
| Mar 31, 2024 | -834.20% |
| Dec 31, 2023 | -4,196.72% |
| Sep 30, 2023 | -509.04% |
| Jun 30, 2023 | -1,085.86% |
| Jun 30, 2022 | -23,022.77% |
| Sep 30, 2021 | -796.76% |
| Sep 30, 2019 | 48.15% |
| Jun 30, 2019 | 49.91% |
| Mar 31, 2019 | 49.84% |
| Dec 31, 2018 | 42.44% |
API Access
Ensysce Biosciences Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ENSC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "ENSC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ENSC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();