Ensysce Biosciences (ENSC) Return on Capital Employed [ROCE] (2018 - 2025)
Ensysce Biosciences' Return on Capital Employed [ROCE] came in at -532.54% for Q3 2025, down 340.68 percentage points from -191.87% a year earlier and down 274.82 percentage points from the prior quarter.
Powered by 
Analysis
Ensysce Biosciences (ENSC) Return on Capital Employed [ROCE] (2018 - 2025) Analysis & Trends
For FY2024, Ensysce Biosciences' Return on Capital Employed [ROCE] was -345.94%, up 766.36 percentage points from FY2023.
- Return on Capital Employed [ROCE] carries a five-year change of -344.26 percentage points (FY2019 to FY2024).
- Going back by year, Return on Capital Employed [ROCE] was -1112.30% in FY2023 (+323.52 pp), -1435.82% in FY2022 and -1.76% in FY2020 (-0.08 pp).
- The Q3 2025 figure represents the lowest quarterly Return on Capital Employed [ROCE] since Q2 2023.
- Year-over-year, Return on Capital Employed [ROCE] increased in five of the last six quarters, with an average year-over-year change of +423.35 percentage points.
- The fastest year-over-year change in Return on Capital Employed [ROCE] over five years came in Q1 2024 (a gain of 1935.42 percentage points), and the weakest in Q1 2023 (a drop of 1947.78 percentage points).
- Business Quant data shows ENSC's Return on Capital Employed [ROCE] at -257.73% (Q2 2025), -205.02% (Q1 2025) and -127.37% (Q4 2024) in the three quarters before Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 46.74% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 17.83% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 17.92% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 6.28% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 19.32% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 9.54% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 16.66% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 11.86% |
| 10 | Ensysce Biosciences | 1.02 Mn | -10.55 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2025 | -532.54% |
| Jun 30, 2025 | -257.73% |
| Mar 31, 2025 | -205.02% |
| Dec 31, 2024 | -127.37% |
| Sep 30, 2024 | -191.87% |
| Jun 30, 2024 | -367.59% |
| Mar 31, 2024 | -443.45% |
| Sep 30, 2023 | -499.10% |
| Jun 30, 2023 | -657.45% |
| Mar 31, 2023 | -2,378.87% |
| Jun 30, 2022 | -1,608.53% |
| Mar 31, 2022 | -431.09% |
| Sep 30, 2021 | -779.92% |
| Jun 30, 2021 | -34.49% |
| Mar 31, 2021 | -29.67% |
| Sep 30, 2020 | -24.11% |
| Jun 30, 2020 | -8.96% |
| Mar 31, 2020 | -3.23% |
| Dec 31, 2019 | -1.67% |
| Sep 30, 2019 | -0.79% |
API Access
Ensysce Biosciences Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=ENSC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "ENSC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=ENSC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();