Ensysce Biosciences ENSC
NASDAQ ENSC
$0.37 0.00 (-1.19%)
At close: Aug 21, 2026 · 4:00 PM EDT

Ensysce Biosciences (ENSC) Operating Income (2018 - 2025)

Ensysce Biosciences (ENSC) posted quarterly Operating Income of -$3.7 million for Q3 2025, down 680.24% year-over-year from $644746.0 in Q3 2024, and down 113.71% quarter-over-quarter from -$1.8 million in Q2 2025.

Ensysce Biosciences (ENSC) Operating Income (2018 - 2025) Analysis & Trends

Ensysce Biosciences (ENSC) has reported Operating Income for 8 consecutive years, with -$3.7 million the latest figure, recorded in Q3 2025.

  • In Q3 2025, Operating Income fell 680.24% year-over-year to -$3.7 million; the TTM figure through Sep 2025 stood at -$11.0 million (down 74.91% YoY), while the FY2024 annual figure was -$6.7 million, up 37.21% from the prior year.
  • Operating Income eased to -$3.7 million in Q3 2025 per ENSC's latest filing, from -$1.8 million in the prior quarter.
  • Across five years, Operating Income topped out at $644746.0 in Q3 2024 and bottomed at -$16.9 million in Q3 2021.
  • Historically, Operating Income has averaged -$3.6 million across 5 years, with a median of -$2.6 million in 2023.
  • Annual changes were most pronounced in 2021 — Operating Income tumbled 4071.91% — and 2024, when it jumped 123.81%.
  • Ensysce Biosciences' Operating Income stood at -$2.0 million in 2021, then sank by 209.0% to -$6.2 million in 2022, then jumped by 49.11% to -$3.2 million in 2023, then retreated by 13.33% to -$3.6 million in 2024, then declined by 4.6% to -$3.7 million in 2025.
  • Business Quant data shows ENSC's Operating Income at -$3.7 million in Q3 2025, -$1.8 million in Q2 2025, and -$2.0 million in Q1 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -815.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 325.05 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 231.44 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -375.75 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -1.55 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 133.12 Mn
10 Ensysce Biosciences 942,649.19 -3.37 Mn - -

Historic Data

Download Data
DateValue
Sep 30, 2025 -3.74 Mn
Jun 30, 2025 -1.75 Mn
Mar 31, 2025 -1.97 Mn
Dec 31, 2024 -3.58 Mn
Sep 30, 2024 644,746.00
Jun 30, 2024 -1.96 Mn
Mar 31, 2024 -1.84 Mn
Dec 31, 2023 -3.16 Mn
Sep 30, 2023 -2.71 Mn
Jun 30, 2023 -2.29 Mn
Mar 31, 2023 -2.56 Mn
Dec 31, 2022 -6.20 Mn
Sep 30, 2022 -6.16 Mn
Jun 30, 2022 -7.06 Mn
Mar 31, 2022 -4.80 Mn
Dec 31, 2021 -2.01 Mn
Sep 30, 2021 -16.89 Mn
Jun 30, 2021 -412,617.00
Mar 31, 2021 -524,273.00
Dec 31, 2020 -1.09 Mn