Ensysce Biosciences (ENSC) EBITDA (2018 - 2025)
Ensysce Biosciences' (ENSC) quarterly EBITDA came in at -$3.7 million in Q3 2025, down 680.24% year-over-year from $644746.0 in Q3 2024, and down 113.71% quarter-over-quarter from -$1.8 million in Q2 2025.
Analysis
Ensysce Biosciences (ENSC) EBITDA (2018 - 2025) Analysis & Trends
Ensysce Biosciences (ENSC) has reported EBITDA for 8 consecutive years, with -$3.7 million the latest figure, recorded in Q3 2025.
- On a quarterly basis, EBITDA fell 680.24% year-over-year to -$3.7 million in Q3 2025; TTM through Sep 2025 was -$11.0 million, a 74.91% decrease from a year earlier, with the FY2024 full-year figure at -$6.7 million, up 37.21% from the prior year.
- EBITDA was -$3.7 million for Q3 2025 at Ensysce Biosciences, down from -$1.8 million in the prior quarter.
- Over five years, EBITDA peaked at $644746.0 in Q3 2024 and troughed at -$16.9 million in Q3 2021.
- A 5-year average of -$3.6 million and a median of -$2.6 million in 2023 frame the typical range for EBITDA.
- Across the five-year window, EBITDA plunged 4071.91% in 2021 and soared 123.81% in 2024, its largest moves.
- Over 5 years, EBITDA stood at -$2.0 million in 2021, then sank by 209.0% to -$6.2 million in 2022, then surged by 49.11% to -$3.2 million in 2023, then declined by 13.33% to -$3.6 million in 2024, then slipped by 4.6% to -$3.7 million in 2025.
- The last three EBITDA figures came in at -$3.7 million (Q3 2025), -$1.8 million (Q2 2025), and -$2.0 million (Q1 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 663.08 Bn | 642.33 Bn | 17.26 Bn | 7.14 Bn |
| 2 | AbbVie | 453.04 Bn | 446.51 Bn | 12.70 Bn | 6.43 Bn |
| 3 | Merck | 370.87 Bn | 363.78 Bn | 12.21 Bn | -584.00 Mn |
| 4 | Novartis Ag | 305.29 Bn | 298.00 Bn | 11.24 Bn | 4.75 Bn |
| 5 | Pfizer | 162.10 Bn | 150.70 Bn | 10.94 Bn | 4.27 Bn |
| 6 | Sanofi | 53.95 Bn | 46.98 Bn | 10.79 Bn | 1.22 Bn |
| 7 | Revolution Medicines | 45.00 Bn | 45.00 Bn | - | -505.13 Mn |
| 8 | Incyte | 25.47 Bn | 20.94 Bn | 1.57 Bn | 697.90 Mn |
| 9 | United Therapeutics | 20.81 Bn | 18.15 Bn | 683.80 Mn | 330.80 Mn |
| 10 | Ensysce Biosciences | 1.18 Mn | -3.46 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2025 | -3.74 Mn |
| Jun 30, 2025 | -1.75 Mn |
| Mar 31, 2025 | -1.97 Mn |
| Dec 31, 2024 | -3.58 Mn |
| Sep 30, 2024 | 644,746.00 |
| Jun 30, 2024 | -1.96 Mn |
| Mar 31, 2024 | -1.84 Mn |
| Dec 31, 2023 | -3.16 Mn |
| Sep 30, 2023 | -2.71 Mn |
| Jun 30, 2023 | -2.29 Mn |
| Mar 31, 2023 | -2.56 Mn |
| Dec 31, 2022 | -6.20 Mn |
| Sep 30, 2022 | -6.16 Mn |
| Jun 30, 2022 | -7.06 Mn |
| Mar 31, 2022 | -4.80 Mn |
| Dec 31, 2021 | -2.01 Mn |
| Sep 30, 2021 | -16.89 Mn |
| Jun 30, 2021 | -412,617.00 |
| Mar 31, 2021 | -524,273.00 |
| Dec 31, 2020 | -1.09 Mn |