Dyne Therapeutics (DYN) EBITDA (2019 - 2026)
Dyne Therapeutics (DYN) recorded quarterly EBITDA of -$121.5 million in Q1 2026, down 8.48% quarter-over-quarter from -$112.0 million in Q4 2025, and down 5.51% on a YoY basis from -$128.5 million in Q1 2025.
Dyne Therapeutics (DYN) EBITDA (2019 - 2026) Analysis & Trends
Dyne Therapeutics' EBITDA history runs 8 years deep, the most recent figure standing at -$121.5 million for Q1 2026.
- In Q1 2026, EBITDA fell 5.51% year-over-year to -$121.5 million; the TTM figure through Mar 2026 stood at -$452.1 million (down 23.27% YoY), while the FY2025 annual figure was -$445.7 million, down 40.43% from the prior year.
- EBITDA was -$121.5 million for Q1 2026 at Dyne Therapeutics, down from -$112.0 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$36.2 million in Q1 2022 to a low of -$121.5 million in Q1 2026.
- Historically, EBITDA has averaged -$75.8 million across 5 years, with a median of -$65.8 million in 2024.
- Biggest YoY gain for EBITDA was 26.15% in 2022; the steepest drop was 75.52% in 2022.
- A 5-year view of EBITDA shows it stood at -$38.4 million in 2022, then slumped by 73.43% to -$66.6 million in 2023, then tumbled by 35.11% to -$90.0 million in 2024, then declined by 24.4% to -$112.0 million in 2025, then retreated by 8.48% to -$121.5 million in 2026.
- The last three EBITDA figures came in at -$121.5 million (Q1 2026), -$112.0 million (Q4 2025), and -$107.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -65.83 Mn |
| 10 | Dyne Therapeutics | 3.00 Bn | 3.00 Bn | - | -121.47 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -121.47 Mn |
| Dec 31, 2025 | -111.98 Mn |
| Sep 30, 2025 | -107.80 Mn |
| Jun 30, 2025 | -110.85 Mn |
| Mar 31, 2025 | -115.13 Mn |
| Dec 31, 2024 | -90.01 Mn |
| Sep 30, 2024 | -96.41 Mn |
| Jun 30, 2024 | -65.21 Mn |
| Mar 31, 2024 | -65.78 Mn |
| Dec 31, 2023 | -66.63 Mn |
| Sep 30, 2023 | -60.17 Mn |
| Jun 30, 2023 | -64.76 Mn |
| Mar 31, 2023 | -43.82 Mn |
| Dec 31, 2022 | -38.42 Mn |
| Sep 30, 2022 | -41.21 Mn |
| Jun 30, 2022 | -52.53 Mn |
| Mar 31, 2022 | -36.24 Mn |
| Dec 31, 2021 | -52.02 Mn |
| Sep 30, 2021 | -42.58 Mn |
| Jun 30, 2021 | -29.93 Mn |