Dyne Therapeutics (DYN) EBITDA (2019 - 2026)

Dyne Therapeutics (DYN) recorded quarterly EBITDA of -$121.5 million in Q1 2026, down 8.48% quarter-over-quarter from -$112.0 million in Q4 2025, and down 5.51% on a YoY basis from -$128.5 million in Q1 2025.

Dyne Therapeutics (DYN) EBITDA (2019 - 2026) Analysis & Trends

Dyne Therapeutics' EBITDA history runs 8 years deep, the most recent figure standing at -$121.5 million for Q1 2026.

  • In Q1 2026, EBITDA fell 5.51% year-over-year to -$121.5 million; the TTM figure through Mar 2026 stood at -$452.1 million (down 23.27% YoY), while the FY2025 annual figure was -$445.7 million, down 40.43% from the prior year.
  • EBITDA was -$121.5 million for Q1 2026 at Dyne Therapeutics, down from -$112.0 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$36.2 million in Q1 2022 to a low of -$121.5 million in Q1 2026.
  • Historically, EBITDA has averaged -$75.8 million across 5 years, with a median of -$65.8 million in 2024.
  • Biggest YoY gain for EBITDA was 26.15% in 2022; the steepest drop was 75.52% in 2022.
  • A 5-year view of EBITDA shows it stood at -$38.4 million in 2022, then slumped by 73.43% to -$66.6 million in 2023, then tumbled by 35.11% to -$90.0 million in 2024, then declined by 24.4% to -$112.0 million in 2025, then retreated by 8.48% to -$121.5 million in 2026.
  • The last three EBITDA figures came in at -$121.5 million (Q1 2026), -$112.0 million (Q4 2025), and -$107.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -13.63 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -14.44 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 Dyne Therapeutics 3.00 Bn 3.00 Bn - -121.47 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -121.47 Mn
Dec 31, 2025 -111.98 Mn
Sep 30, 2025 -107.80 Mn
Jun 30, 2025 -110.85 Mn
Mar 31, 2025 -115.13 Mn
Dec 31, 2024 -90.01 Mn
Sep 30, 2024 -96.41 Mn
Jun 30, 2024 -65.21 Mn
Mar 31, 2024 -65.78 Mn
Dec 31, 2023 -66.63 Mn
Sep 30, 2023 -60.17 Mn
Jun 30, 2023 -64.76 Mn
Mar 31, 2023 -43.82 Mn
Dec 31, 2022 -38.42 Mn
Sep 30, 2022 -41.21 Mn
Jun 30, 2022 -52.53 Mn
Mar 31, 2022 -36.24 Mn
Dec 31, 2021 -52.02 Mn
Sep 30, 2021 -42.58 Mn
Jun 30, 2021 -29.93 Mn