Design Therapeutics (DSGN) Return on Equity [ROE] (2021 - 2026)
Design Therapeutics (DSGN) posted Return on Equity [ROE] of -33.72% for Q2 2026, down 4.92 percentage points from -28.80% a year earlier and down 1.34 percentage points from the prior quarter.
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Analysis
Design Therapeutics (DSGN) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, Design Therapeutics' Return on Equity [ROE] came in at -30.70%, down 11.62 percentage points from FY2024.
- Annual Return on Equity [ROE] shows a four-year change of -11.38 percentage points (FY2021 to FY2025).
- In prior years, Design Therapeutics' Return on Equity [ROE] was -19.08% in FY2024 (+3.02 pp), -22.10% in FY2023 (-3.05 pp), -19.06% in FY2022 (+0.27 pp) and -19.33% in FY2021.
- Quarterly Return on Equity [ROE] has run from a low of -33.86% in Q4 2025 to a high of -7.20% in Q3 2021 over five years.
- On a year-over-year basis, Return on Equity [ROE] has declined in each of the last five quarters, with an average year-over-year change of -3.80 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Return on Equity [ROE] in the past five years was Q3 2024, with a gain of 8.47 percentage points; the weakest was Q4 2025, with a drop of 13.81 percentage points.
- According to Business Quant data, Return on Equity [ROE] for the three prior quarters was -32.38% (Q1 2026), -33.86% (Q4 2025) and -32.68% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Design Therapeutics | 786.63 Mn | -69.40 Mn | - | -33.72% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -33.72% |
| Mar 31, 2026 | -32.38% |
| Dec 31, 2025 | -33.86% |
| Sep 30, 2025 | -32.68% |
| Jun 30, 2025 | -28.80% |
| Mar 31, 2025 | -23.91% |
| Dec 31, 2024 | -20.05% |
| Sep 30, 2024 | -19.88% |
| Jun 30, 2024 | -21.42% |
| Mar 31, 2024 | -24.72% |
| Dec 31, 2023 | -27.79% |
| Sep 30, 2023 | -28.35% |
| Jun 30, 2023 | -27.17% |
| Mar 31, 2023 | -23.71% |
| Dec 31, 2022 | -20.23% |
| Sep 30, 2022 | -17.00% |
| Jun 30, 2022 | -14.15% |
| Mar 31, 2022 | -11.57% |
| Dec 31, 2021 | -9.26% |
| Sep 30, 2021 | -7.20% |
API Access
Design Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=DSGN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "DSGN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=DSGN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();