Design Therapeutics (DSGN) Operating Income (2020 - 2026)

Design Therapeutics' (DSGN) quarterly Operating Income came in at -$19.7 million in Q1 2026, up 3.49% year-on-year from -$19.0 million in Q1 2025, and down 8.46% quarter-over-quarter from -$18.2 million in Q4 2025.

Design Therapeutics (DSGN) Operating Income (2020 - 2026) Analysis & Trends

Design Therapeutics has disclosed Operating Income across 7 years of filings, most recently posting -$19.7 million for Q1 2026.

  • Operating Income for Q1 2026 came in at -$19.7 million, up 3.49% year-over-year; the trailing twelve-month figure through Mar 2026 was -$78.8 million (down 15.14% YoY), and the FY2025 annual result was -$79.5 million, down 27.39% from the prior year.
  • Operating Income came in at -$19.7 million for Q1 2026 at Design Therapeutics, down from -$18.2 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$13.4 million in Q1 2022 to a low of -$22.6 million in Q2 2023.
  • The 5-year median for Operating Income is -$18.8 million (2023), against an average of -$18.1 million.
  • Across the five-year window, Operating Income sank 135.39% in 2022 and jumped 33.49% in 2024, its largest moves.
  • Design Therapeutics' Operating Income stood at -$19.4 million in 2022, then climbed by 22.02% to -$15.1 million in 2023, then fell by 10.4% to -$16.7 million in 2024, then declined by 8.84% to -$18.2 million in 2025, then declined by 8.46% to -$19.7 million in 2026.
  • The last three Operating Income figures came in at -$19.7 million (Q1 2026), -$18.2 million (Q4 2025), and -$19.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Design Therapeutics 763.94 Mn 541.11 Mn - -19.71 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -19.71 Mn
Dec 31, 2025 -18.17 Mn
Sep 30, 2025 -19.31 Mn
Jun 30, 2025 -21.57 Mn
Mar 31, 2025 -20.42 Mn
Dec 31, 2024 -16.69 Mn
Sep 30, 2024 -16.25 Mn
Jun 30, 2024 -15.04 Mn
Mar 31, 2024 -14.40 Mn
Dec 31, 2023 -15.12 Mn
Sep 30, 2023 -18.82 Mn
Jun 30, 2023 -22.60 Mn
Mar 31, 2023 -21.65 Mn
Dec 31, 2022 -19.39 Mn
Sep 30, 2022 -19.19 Mn
Jun 30, 2022 -15.64 Mn
Mar 31, 2022 -13.37 Mn
Dec 31, 2021 -11.13 Mn
Sep 30, 2021 -11.34 Mn
Jun 30, 2021 -7.69 Mn