Design Therapeutics (DSGN) Operating Income (2020 - 2026)

Design Therapeutics (DSGN) reported Operating Income of -$19.7 million for Q1 2026, up 3.49% on a YoY basis from -$19.0 million in Q1 2025, and down 8.46% sequentially from -$18.2 million in Q4 2025.

Design Therapeutics (DSGN) Operating Income (2020 - 2026) Analysis & Trends

Design Therapeutics (DSGN) has 7 years of Operating Income data on file, last reported at -$19.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income rose 3.49% year-over-year to -$19.7 million; the trailing twelve-month figure through Mar 2026 stood at -$78.8 million (down 15.14% YoY), and the FY2025 full-year result was -$79.5 million, down 27.39% from the prior year.
  • Operating Income slipped to -$19.7 million in Q1 2026, from -$18.2 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$13.4 million in Q1 2022 to a low of -$22.6 million in Q2 2023.
  • A 5-year average of -$18.1 million and a median of -$18.8 million in 2023 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income tumbled 135.39% in 2022 and jumped 33.49% in 2024, its largest moves.
  • Tracing DSGN's Operating Income over 5 years: stood at -$19.4 million in 2022, then advanced by 22.02% to -$15.1 million in 2023, then declined by 10.4% to -$16.7 million in 2024, then dropped by 8.84% to -$18.2 million in 2025, then dropped by 8.46% to -$19.7 million in 2026.
  • Business Quant data shows DSGN's Operating Income at -$19.7 million in Q1 2026, -$18.2 million in Q4 2025, and -$19.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Design Therapeutics 714.48 Mn 491.66 Mn - -19.71 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -19.71 Mn
Dec 31, 2025 -18.17 Mn
Sep 30, 2025 -19.31 Mn
Jun 30, 2025 -21.57 Mn
Mar 31, 2025 -20.42 Mn
Dec 31, 2024 -16.69 Mn
Sep 30, 2024 -16.25 Mn
Jun 30, 2024 -15.04 Mn
Mar 31, 2024 -14.40 Mn
Dec 31, 2023 -15.12 Mn
Sep 30, 2023 -18.82 Mn
Jun 30, 2023 -22.60 Mn
Mar 31, 2023 -21.65 Mn
Dec 31, 2022 -19.39 Mn
Sep 30, 2022 -19.19 Mn
Jun 30, 2022 -15.64 Mn
Mar 31, 2022 -13.37 Mn
Dec 31, 2021 -11.13 Mn
Sep 30, 2021 -11.34 Mn
Jun 30, 2021 -7.69 Mn