Design Therapeutics (DSGN) EBITDA (2020 - 2026)
Design Therapeutics' (DSGN) quarterly EBITDA came in at -$19.7 million in Q1 2026, down 11.08% year-on-year from -$22.2 million in Q1 2025, and down 8.46% quarter-over-quarter from -$18.2 million in Q4 2025.
Design Therapeutics (DSGN) EBITDA (2020 - 2026) Analysis & Trends
Design Therapeutics has disclosed EBITDA across 7 years of filings, most recently posting -$19.7 million for Q1 2026.
- EBITDA for Q1 2026 came in at -$19.7 million, down 11.08% year-over-year; the trailing twelve-month figure through Mar 2026 was -$78.8 million (down 35.35% YoY), and the FY2025 annual result was -$79.5 million, down 27.39% from the prior year.
- EBITDA came in at -$19.7 million for Q1 2026 at Design Therapeutics, down from -$18.2 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$10.5 million in Q4 2023 to a low of -$21.6 million in Q2 2025.
- The 5-year median for EBITDA is -$16.8 million (2022), against an average of -$16.4 million.
- Across the five-year window, EBITDA sank 153.05% in 2022 and soared 40.65% in 2024, its largest moves.
- Design Therapeutics' EBITDA stood at -$16.8 million in 2022, then soared by 37.65% to -$10.5 million in 2023, then tumbled by 59.04% to -$16.7 million in 2024, then declined by 8.84% to -$18.2 million in 2025, then declined by 8.46% to -$19.7 million in 2026.
- The last three EBITDA figures came in at -$19.7 million (Q1 2026), -$18.2 million (Q4 2025), and -$19.3 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Design Therapeutics | 763.94 Mn | 541.11 Mn | - | -19.71 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -19.71 Mn |
| Dec 31, 2025 | -18.17 Mn |
| Sep 30, 2025 | -19.31 Mn |
| Jun 30, 2025 | -21.57 Mn |
| Mar 31, 2025 | -17.74 Mn |
| Dec 31, 2024 | -16.69 Mn |
| Sep 30, 2024 | -11.91 Mn |
| Jun 30, 2024 | -11.84 Mn |
| Mar 31, 2024 | -11.33 Mn |
| Dec 31, 2023 | -10.50 Mn |
| Sep 30, 2023 | -15.07 Mn |
| Jun 30, 2023 | -19.96 Mn |
| Mar 31, 2023 | -17.92 Mn |
| Dec 31, 2022 | -16.84 Mn |
| Sep 30, 2022 | -19.25 Mn |
| Jun 30, 2022 | -15.99 Mn |
| Mar 31, 2022 | -14.34 Mn |
| Dec 31, 2021 | -11.31 Mn |
| Sep 30, 2021 | -11.31 Mn |
| Jun 30, 2021 | -7.65 Mn |