Design Therapeutics (DSGN) EBITDA (2020 - 2026)

Design Therapeutics' (DSGN) quarterly EBITDA came in at -$19.7 million in Q1 2026, down 11.08% year-on-year from -$22.2 million in Q1 2025, and down 8.46% quarter-over-quarter from -$18.2 million in Q4 2025.

Design Therapeutics (DSGN) EBITDA (2020 - 2026) Analysis & Trends

Design Therapeutics has disclosed EBITDA across 7 years of filings, most recently posting -$19.7 million for Q1 2026.

  • EBITDA for Q1 2026 came in at -$19.7 million, down 11.08% year-over-year; the trailing twelve-month figure through Mar 2026 was -$78.8 million (down 35.35% YoY), and the FY2025 annual result was -$79.5 million, down 27.39% from the prior year.
  • EBITDA came in at -$19.7 million for Q1 2026 at Design Therapeutics, down from -$18.2 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$10.5 million in Q4 2023 to a low of -$21.6 million in Q2 2025.
  • The 5-year median for EBITDA is -$16.8 million (2022), against an average of -$16.4 million.
  • Across the five-year window, EBITDA sank 153.05% in 2022 and soared 40.65% in 2024, its largest moves.
  • Design Therapeutics' EBITDA stood at -$16.8 million in 2022, then soared by 37.65% to -$10.5 million in 2023, then tumbled by 59.04% to -$16.7 million in 2024, then declined by 8.84% to -$18.2 million in 2025, then declined by 8.46% to -$19.7 million in 2026.
  • The last three EBITDA figures came in at -$19.7 million (Q1 2026), -$18.2 million (Q4 2025), and -$19.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Design Therapeutics 763.94 Mn 541.11 Mn - -19.71 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -19.71 Mn
Dec 31, 2025 -18.17 Mn
Sep 30, 2025 -19.31 Mn
Jun 30, 2025 -21.57 Mn
Mar 31, 2025 -17.74 Mn
Dec 31, 2024 -16.69 Mn
Sep 30, 2024 -11.91 Mn
Jun 30, 2024 -11.84 Mn
Mar 31, 2024 -11.33 Mn
Dec 31, 2023 -10.50 Mn
Sep 30, 2023 -15.07 Mn
Jun 30, 2023 -19.96 Mn
Mar 31, 2023 -17.92 Mn
Dec 31, 2022 -16.84 Mn
Sep 30, 2022 -19.25 Mn
Jun 30, 2022 -15.99 Mn
Mar 31, 2022 -14.34 Mn
Dec 31, 2021 -11.31 Mn
Sep 30, 2021 -11.31 Mn
Jun 30, 2021 -7.65 Mn