Design Therapeutics (DSGN) EBITDA (2020 - 2026)
Design Therapeutics recorded quarterly EBITDA of -$19.7 million in Q1 2026, down 8.46% quarter-over-quarter from -$18.2 million in Q4 2025, and down 11.08% year-over-year from -$22.2 million in Q1 2025.
Design Therapeutics' EBITDA history runs 7 years deep, the most recent figure standing at -$19.7 million for Q1 2026.
- In Q1 2026, EBITDA fell 11.08% year-over-year to -$19.7 million; the TTM figure through Mar 2026 stood at -$78.8 million (down 35.35% YoY), while the FY2025 annual figure was -$79.5 million, down 27.39% from the prior year.
- EBITDA came in at -$19.7 million for Q1 2026 at Design Therapeutics, down from -$18.2 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$10.5 million in Q4 2023 to a low of -$21.6 million in Q2 2025.
- A 5-year average of -$16.4 million and a median of -$16.8 million in 2022 frame the typical range for EBITDA.
- Across the five-year window, EBITDA plunged 153.05% in 2022 and jumped 40.65% in 2024, its largest moves.
- Design Therapeutics' EBITDA stood at -$16.8 million in 2022, then jumped by 37.65% to -$10.5 million in 2023, then slumped by 59.04% to -$16.7 million in 2024, then fell by 8.84% to -$18.2 million in 2025, then fell by 8.46% to -$19.7 million in 2026.
- According to Business Quant data, EBITDA over the past three periods registered -$19.7 million, -$18.2 million, and -$19.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 661.60 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 201.19 Mn |
| 10 | Design Therapeutics | 640.15 Mn | 417.32 Mn | - | -19.71 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -19.71 Mn |
| Dec 31, 2025 | -18.17 Mn |
| Sep 30, 2025 | -19.31 Mn |
| Jun 30, 2025 | -21.57 Mn |
| Mar 31, 2025 | -17.74 Mn |
| Dec 31, 2024 | -16.69 Mn |
| Sep 30, 2024 | -11.91 Mn |
| Jun 30, 2024 | -11.84 Mn |
| Mar 31, 2024 | -11.33 Mn |
| Dec 31, 2023 | -10.50 Mn |
| Sep 30, 2023 | -15.07 Mn |
| Jun 30, 2023 | -19.96 Mn |
| Mar 31, 2023 | -17.92 Mn |
| Dec 31, 2022 | -16.84 Mn |
| Sep 30, 2022 | -19.25 Mn |
| Jun 30, 2022 | -15.99 Mn |
| Mar 31, 2022 | -14.34 Mn |
| Dec 31, 2021 | -11.31 Mn |
| Sep 30, 2021 | -11.31 Mn |
| Jun 30, 2021 | -7.65 Mn |
| Mar 31, 2021 | -5.67 Mn |
| Dec 31, 2020 | -3.86 Mn |
| Sep 30, 2020 | -2.38 Mn |
| Jun 30, 2020 | -1.46 Mn |
| Mar 31, 2020 | -623,000.00 |