Design Therapeutics (DSGN) EBIT (2020 - 2026)

Design Therapeutics recorded quarterly EBIT of -$19.7 million in Q1 2026, down 8.46% quarter-over-quarter from -$18.2 million in Q4 2025, and up 3.49% year-over-year from -$19.0 million in Q1 2025.

Design Therapeutics' EBIT history runs 7 years deep, the most recent figure standing at -$19.7 million for Q1 2026.

  • In Q1 2026, EBIT rose 3.49% year-over-year to -$19.7 million; the TTM figure through Mar 2026 stood at -$78.8 million (down 15.14% YoY), while the FY2025 annual figure was -$79.5 million, down 27.39% from the prior year.
  • EBIT came in at -$19.7 million for Q1 2026 at Design Therapeutics, down from -$18.2 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of -$13.4 million in Q1 2022 to a low of -$22.6 million in Q2 2023.
  • A 5-year average of -$18.1 million and a median of -$18.8 million in 2023 frame the typical range for EBIT.
  • Across the five-year window, EBIT plunged 135.39% in 2022 and surged 33.49% in 2024, its largest moves.
  • Design Therapeutics' EBIT stood at -$19.4 million in 2022, then grew by 22.02% to -$15.1 million in 2023, then retreated by 10.4% to -$16.7 million in 2024, then fell by 8.84% to -$18.2 million in 2025, then fell by 8.46% to -$19.7 million in 2026.
  • According to Business Quant data, EBIT over the past three periods registered -$19.7 million, -$18.2 million, and -$19.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Design Therapeutics 640.15 Mn 417.32 Mn - -19.71 Mn

Historic Data

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DateValue
Mar 31, 2026 -19.71 Mn
Dec 31, 2025 -18.17 Mn
Sep 30, 2025 -19.31 Mn
Jun 30, 2025 -21.57 Mn
Mar 31, 2025 -20.42 Mn
Dec 31, 2024 -16.69 Mn
Sep 30, 2024 -16.25 Mn
Jun 30, 2024 -15.04 Mn
Mar 31, 2024 -14.40 Mn
Dec 31, 2023 -15.12 Mn
Sep 30, 2023 -18.82 Mn
Jun 30, 2023 -22.60 Mn
Mar 31, 2023 -21.65 Mn
Dec 31, 2022 -19.39 Mn
Sep 30, 2022 -19.19 Mn
Jun 30, 2022 -15.64 Mn
Mar 31, 2022 -13.37 Mn
Dec 31, 2021 -11.13 Mn
Sep 30, 2021 -11.34 Mn
Jun 30, 2021 -7.69 Mn
Mar 31, 2021 -5.68 Mn
Dec 31, 2020 -3.86 Mn
Sep 30, 2020 -2.38 Mn
Jun 30, 2020 -1.46 Mn
Mar 31, 2020 -623,000.00