Definium Therapeutics (DFTX) Profit After Tax (2021 - 2026)

Definium Therapeutics (DFTX) posted quarterly Profit After Tax of -$77.4 million for Q1 2026, down 231.09% year-over-year from $59.0 million in Q1 2025, and down 52.83% quarter-over-quarter from -$50.6 million in Q4 2025.

Definium Therapeutics (DFTX) Profit After Tax (2021 - 2026) Analysis & Trends

Definium Therapeutics (DFTX) has reported Profit After Tax for 6 consecutive years, with -$77.4 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Profit After Tax fell 231.09% year-over-year to -$77.4 million; the TTM figure through Mar 2026 stood at -$237.8 million (down 208.13% YoY), while the FY2025 annual figure was -$183.8 million, down 69.86% from the prior year.
  • Profit After Tax retreated to -$77.4 million in Q1 2026 per DFTX's latest filing, from -$50.6 million in the prior quarter.
  • Across five years, Profit After Tax topped out at -$4.9 million in Q4 2022 and bottomed at -$77.4 million in Q1 2026.
  • Historically, Profit After Tax has averaged -$30.7 million across 5 years, with a median of -$24.3 million in 2023.
  • Annual changes were most pronounced in 2024 — Profit After Tax jumped 80.08% — and 2025, when it slumped 629.71%.
  • Definium Therapeutics' Profit After Tax stood at -$4.9 million in 2022, then sank by 395.57% to -$24.3 million in 2023, then plunged by 41.02% to -$34.3 million in 2024, then plunged by 47.73% to -$50.6 million in 2025, then tumbled by 52.83% to -$77.4 million in 2026.
  • Business Quant data shows DFTX's Profit After Tax at -$77.4 million in Q1 2026, -$50.6 million in Q4 2025, and -$67.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 472.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -644.37 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 237.01 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,087.27
7 Royalty Pharma 33.72 Bn 35.84 Bn - 81.49 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 164.49 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -16.62 Mn
10 Definium Therapeutics 4.72 Bn 4.72 Bn - -159.39 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -159.39 Mn
Mar 31, 2026 -77.36 Mn
Dec 31, 2025 -50.62 Mn
Sep 30, 2025 -67.07 Mn
Jun 30, 2025 -42.74 Mn
Mar 31, 2025 -23.37 Mn
Dec 31, 2024 -34.27 Mn
Sep 30, 2024 -13.68 Mn
Jun 30, 2024 -5.86 Mn
Mar 31, 2024 -53.91 Mn
Dec 31, 2023 -24.30 Mn
Sep 30, 2023 -17.51 Mn
Jun 30, 2023 -29.41 Mn
Mar 31, 2023 -24.80 Mn
Dec 31, 2022 -4.90 Mn
Sep 30, 2022 -16.49 Mn
Jun 30, 2022 -16.96 Mn
Mar 31, 2022 -18.45 Mn
Dec 31, 2021 -16.45 Mn
Sep 30, 2021 -17.58 Mn