Growth Metrics

Definium Therapeutics (DFTX) Profit After Tax (2019 - 2026)

Definium Therapeutics (DFTX) reported Profit After Tax of -$77.1 million for Q1 2026, down 230.21% year-over-year from $59.2 million in Q1 2025, and down 52.86% on a QoQ basis from -$50.4 million in Q4 2025.

Definium Therapeutics (DFTX) has 8 years of Profit After Tax data on file, last reported at -$77.1 million in Q1 2026.

  • Quarterly Profit After Tax fell 230.21% year-over-year to -$77.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$237.5 million (down 206.01% YoY) and the FY2025 annual result came in at -$183.8 million, down 69.12% from the prior year.
  • Profit After Tax retreated to -$77.1 million in Q1 2026 per DFTX's latest filing, from -$50.4 million in the prior quarter.
  • Across five years, Profit After Tax topped out at -$4.9 million in Q4 2022 and bottomed at -$77.1 million in Q1 2026.
  • The 5-year median for Profit After Tax is -$23.9 million (2023), against an average of -$30.7 million.
  • The widest annual swing landed in 2024, when Profit After Tax jumped 79.9%; it then tumbled 630.17% in 2025.
  • Tracing DFTX's Profit After Tax over 5 years: stood at -$4.9 million in 2022, then slumped by 386.72% to -$23.9 million in 2023, then slumped by 45.58% to -$34.7 million in 2024, then plunged by 45.18% to -$50.4 million in 2025, then sank by 52.86% to -$77.1 million in 2026.
  • Per Business Quant, the three latest DFTX Profit After Tax figures stand at -$77.1 million (Q1 2026), -$50.4 million (Q4 2025), and -$67.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.99 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 30.90 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.63 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 205.99 Mn
10 Definium Therapeutics 2.42 Bn 2.06 Bn - -77.10 Mn

Historic Data

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DateValue
Mar 31, 2026 -77.10 Mn
Dec 31, 2025 -50.44 Mn
Sep 30, 2025 -67.27 Mn
Jun 30, 2025 -42.74 Mn
Mar 31, 2025 -23.35 Mn
Dec 31, 2024 -34.74 Mn
Sep 30, 2024 -13.68 Mn
Jun 30, 2024 -5.85 Mn
Mar 31, 2024 -54.40 Mn
Dec 31, 2023 -23.86 Mn
Sep 30, 2023 -17.92 Mn
Jun 30, 2023 -29.13 Mn
Mar 31, 2023 -24.82 Mn
Dec 31, 2022 -4.90 Mn
Sep 30, 2022 -16.49 Mn
Jun 30, 2022 -16.96 Mn
Mar 31, 2022 -18.45 Mn
Dec 31, 2021 -16.83 Mn
Sep 30, 2021 -17.20 Mn
Jun 30, 2021 -45.25 Mn
Mar 31, 2021 -13.76 Mn
Dec 31, 2020 -13.93 Mn
Sep 30, 2020 -8.68 Mn
Jun 30, 2020 -5.72 Mn
Mar 31, 2020 -7.02 Mn
Dec 31, 2019 -3.77 Mn