Definium Therapeutics (DFTX) Operating Income (2019 - 2026)
Definium Therapeutics (DFTX) reported Operating Income of -$59.2 million for Q1 2026, down 84.15% year-over-year from -$373.6 million in Q1 2025, and down 24.47% quarter-over-quarter from -$47.6 million in Q4 2025.
Definium Therapeutics (DFTX) Operating Income (2019 - 2026) Analysis & Trends
Definium Therapeutics (DFTX) has 7 years of Operating Income data on file, last reported at -$59.2 million in Q1 2026.
- Operating Income for Q1 2026 came in at -$59.2 million, down 84.15% year-over-year; the trailing twelve-month figure through Mar 2026 was -$193.4 million (down 69.81% YoY), and the FY2025 annual result was -$166.3 million, down 60.04% from the prior year.
- Operating Income retreated to -$59.2 million in Q1 2026 per DFTX's latest filing, from -$47.6 million in the prior quarter.
- Over five years, Operating Income peaked at -$13.9 million in Q4 2022 and troughed at -$59.2 million in Q1 2026.
- A 5-year average of -$28.8 million and a median of -$24.5 million in 2024 frame the typical range for Operating Income.
- On a YoY basis, Operating Income climbed as much as 62.53% in 2022 and fell as far as 124.6% in 2022.
- A 5-year view of Operating Income shows it stood at -$13.9 million in 2022, then tumbled by 59.75% to -$22.2 million in 2023, then plunged by 46.19% to -$32.5 million in 2024, then tumbled by 46.57% to -$47.6 million in 2025, then fell by 24.47% to -$59.2 million in 2026.
- Business Quant data shows DFTX's Operating Income at -$59.2 million in Q1 2026, -$47.6 million in Q4 2025, and -$45.7 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Definium Therapeutics | 2.46 Bn | 2.09 Bn | - | -59.22 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -59.22 Mn |
| Dec 31, 2025 | -47.58 Mn |
| Sep 30, 2025 | -45.67 Mn |
| Jun 30, 2025 | -40.90 Mn |
| Mar 31, 2025 | -32.16 Mn |
| Dec 31, 2024 | -32.46 Mn |
| Sep 30, 2024 | -24.79 Mn |
| Jun 30, 2024 | -24.46 Mn |
| Mar 31, 2024 | -22.20 Mn |
| Dec 31, 2023 | -22.21 Mn |
| Sep 30, 2023 | -21.62 Mn |
| Jun 30, 2023 | -29.18 Mn |
| Mar 31, 2023 | -20.86 Mn |
| Dec 31, 2022 | -13.90 Mn |
| Sep 30, 2022 | -16.98 Mn |
| Jun 30, 2022 | -16.94 Mn |
| Mar 31, 2022 | -18.51 Mn |
| Dec 31, 2021 | 56.52 Mn |
| Sep 30, 2021 | -17.23 Mn |
| Jun 30, 2021 | -45.22 Mn |