Definium Therapeutics DFTX
NASDAQ DFTX
$38.09 +0.09 (+0.24%)
As of: Sep 4, 2026 · 3:59 PM EDT

Definium Therapeutics (DFTX) Operating Income (2021 - 2026)

Definium Therapeutics (DFTX) posted quarterly Operating Income of -$59.2 million for Q1 2026, down 84.15% year-over-year from -$373.6 million in Q1 2025, and down 24.47% quarter-over-quarter from -$47.6 million in Q4 2025.

Analysis

Definium Therapeutics (DFTX) Operating Income (2021 - 2026) Analysis & Trends

Definium Therapeutics (DFTX) has reported Operating Income for 6 consecutive years, with -$59.2 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Income fell 84.15% year-over-year to -$59.2 million; the TTM figure through Mar 2026 stood at -$193.4 million (down 69.81% YoY), while the FY2025 annual figure was -$166.3 million, down 60.04% from the prior year.
  • Operating Income declined to -$59.2 million in Q1 2026 per DFTX's latest filing, from -$47.6 million in the prior quarter.
  • Across five years, Operating Income topped out at -$13.9 million in Q4 2022 and bottomed at -$59.2 million in Q1 2026.
  • Historically, Operating Income has averaged -$28.8 million across 5 years, with a median of -$24.5 million in 2024.
  • Annual changes were most pronounced in 2022 — Operating Income surged 62.53% — and 2025, when it plunged 84.21%.
  • Definium Therapeutics' Operating Income stood at -$13.9 million in 2022, then plunged by 59.75% to -$22.2 million in 2023, then sank by 46.19% to -$32.5 million in 2024, then plunged by 46.57% to -$47.6 million in 2025, then retreated by 24.47% to -$59.2 million in 2026.
  • Business Quant data shows DFTX's Operating Income at -$59.2 million in Q1 2026, -$47.6 million in Q4 2025, and -$45.7 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -505.13 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 133.12 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -1.55 Mn
10 Definium Therapeutics 4.23 Bn 4.23 Bn - -75.08 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -75.08 Mn
Mar 31, 2026 -59.22 Mn
Dec 31, 2025 -47.58 Mn
Sep 30, 2025 -45.67 Mn
Jun 30, 2025 -40.90 Mn
Mar 31, 2025 -32.16 Mn
Dec 31, 2024 -32.46 Mn
Sep 30, 2024 -24.79 Mn
Jun 30, 2024 -24.46 Mn
Mar 31, 2024 -22.20 Mn
Dec 31, 2023 -22.21 Mn
Sep 30, 2023 -21.62 Mn
Jun 30, 2023 -29.18 Mn
Mar 31, 2023 -20.86 Mn
Dec 31, 2022 -13.90 Mn
Sep 30, 2022 -16.98 Mn
Jun 30, 2022 -16.94 Mn
Mar 31, 2022 -18.51 Mn
Dec 31, 2021 -17.56 Mn
Sep 30, 2021 -17.23 Mn