Growth Metrics

Definium Therapeutics (DFTX) EBIT (2019 - 2026)

Definium Therapeutics (DFTX) reported EBIT of -$59.2 million for Q1 2026, down 84.15% year-over-year from -$373.6 million in Q1 2025, and down 24.47% on a QoQ basis from -$47.6 million in Q4 2025.

Definium Therapeutics (DFTX) has 8 years of EBIT data on file, last reported at -$59.2 million in Q1 2026.

  • Quarterly EBIT fell 84.15% year-over-year to -$59.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$193.4 million (down 69.81% YoY) and the FY2025 annual result came in at -$166.3 million, down 60.04% from the prior year.
  • EBIT slipped to -$59.2 million in Q1 2026 per DFTX's latest filing, from -$47.6 million in the prior quarter.
  • Across five years, EBIT topped out at -$13.9 million in Q4 2022 and bottomed at -$59.2 million in Q1 2026.
  • The 5-year median for EBIT is -$24.5 million (2024), against an average of -$28.8 million.
  • Peak annual rise in EBIT reached 62.53% in 2022, while the deepest fall reached 124.6% in 2022.
  • Tracing DFTX's EBIT over 5 years: stood at -$13.9 million in 2022, then sank by 59.75% to -$22.2 million in 2023, then slumped by 46.19% to -$32.5 million in 2024, then sank by 46.57% to -$47.6 million in 2025, then dropped by 24.47% to -$59.2 million in 2026.
  • Per Business Quant, the three latest DFTX EBIT figures stand at -$59.2 million (Q1 2026), -$47.6 million (Q4 2025), and -$45.7 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.97 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 268.64 Mn
10 Definium Therapeutics 2.42 Bn 2.06 Bn - -59.22 Mn

Historic Data

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DateValue
Mar 31, 2026 -59.22 Mn
Dec 31, 2025 -47.58 Mn
Sep 30, 2025 -45.67 Mn
Jun 30, 2025 -40.90 Mn
Mar 31, 2025 -32.16 Mn
Dec 31, 2024 -32.46 Mn
Sep 30, 2024 -24.79 Mn
Jun 30, 2024 -24.46 Mn
Mar 31, 2024 -22.20 Mn
Dec 31, 2023 -22.21 Mn
Sep 30, 2023 -21.62 Mn
Jun 30, 2023 -29.18 Mn
Mar 31, 2023 -20.86 Mn
Dec 31, 2022 -13.90 Mn
Sep 30, 2022 -16.98 Mn
Jun 30, 2022 -16.94 Mn
Mar 31, 2022 -18.51 Mn
Dec 31, 2021 56.52 Mn
Sep 30, 2021 -17.23 Mn
Jun 30, 2021 -45.22 Mn
Mar 31, 2021 -13.85 Mn
Dec 31, 2020 750,000.00
Sep 30, 2020 -8.68 Mn
Jun 30, 2020 -5.72 Mn
Mar 31, 2020 -7.03 Mn
Dec 31, 2019 -10.73 Mn