Cryoport (CYRX) Operating Margin (2010 - 2026)
Cryoport (CYRX) reported Operating Margin of -20.50% for Q2 2026, up 0.73 percentage points from -21.23% a year earlier but down 0.39 percentage points from the prior quarter.
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Analysis
Cryoport (CYRX) Operating Margin (2010 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Cryoport's Operating Margin came in at -21.25%, up 4.60 percentage points year-over-year; for FY2025, it came in at -20.89%, up 56.72 percentage points from FY2024.
- Operating Margin has a five-year change of +17.24 percentage points (FY2020 to FY2025).
- By year, Operating Margin came in at -77.61% in FY2024 (-18.00 pp), -59.61% in FY2023 (-46.16 pp), -13.45% in FY2022 (-5.44 pp) and -8.01% in FY2021 (+30.12 pp).
- Five-year quarterly Operating Margin spans a low of -196.50% in Q2 2024 and a high of -8.07% in Q3 2021.
- Year over year, Operating Margin gained in five of the last seven quarters, with an average year-over-year change of +31.31 percentage points.
- The high point for year-over-year Operating Margin in five years was Q2 2025 (a gain of 175.27 percentage points); the low point was Q2 2024 (a drop of 164.35 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -20.11% (Q1 2026), -22.07% (Q4 2025) and -22.45% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Union Pacific | 162.83 Bn | 157.35 Bn | - | 40.25% |
| 2 | Csx | 86.94 Bn | 83.15 Bn | - | 38.27% |
| 3 | Canadian Pacific Kansas City | 76.07 Bn | 75.78 Bn | - | 35.35% |
| 4 | United Parcel Service | 70.39 Bn | 47.31 Bn | - | 4.07% |
| 5 | Norfolk Southern | 70.35 Bn | 64.99 Bn | - | 32.44% |
| 6 | Fedex | 68.01 Bn | 33.95 Bn | - | 6.20% |
| 7 | Delta Air Lines | 55.83 Bn | 38.01 Bn | - | 9.43% |
| 8 | Old Dominion Freight Line | 36.82 Bn | 36.08 Bn | - | 29.94% |
| 9 | Ryanair Holdings | 28.96 Bn | 12.97 Bn | 3.13 Bn | 13.12% |
| 10 | Cryoport | 877.23 Mn | -755.62 Mn | 22.82 Mn | -20.50% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -20.50% |
| Mar 31, 2026 | -20.11% |
| Dec 31, 2025 | -22.07% |
| Sep 30, 2025 | -22.45% |
| Jun 30, 2025 | -21.23% |
| Mar 31, 2025 | -17.53% |
| Dec 31, 2024 | -30.75% |
| Sep 30, 2024 | -34.94% |
| Jun 30, 2024 | -196.50% |
| Mar 31, 2024 | -46.95% |
| Sep 30, 2023 | -30.11% |
| Jun 30, 2023 | -32.15% |
| Mar 31, 2023 | -15.99% |
| Dec 31, 2022 | -18.28% |
| Sep 30, 2022 | -12.91% |
| Jun 30, 2022 | -8.18% |
| Mar 31, 2022 | -14.95% |
| Dec 31, 2021 | -14.82% |
| Sep 30, 2021 | -8.07% |
| Jun 30, 2021 | -6.67% |
API Access
Cryoport Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CYRX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CYRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CYRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();