Cryoport (CYRX) Operating Margin (2010 - 2026)
Cryoport (CYRX) posted quarterly Operating Margin of 20.11% for Q1 2026, down 258.0% year-over-year from 12.73% in Q1 2025, and up 8.87% quarter-over-quarter from 22.07% in Q4 2025.
Cryoport (CYRX) Operating Margin (2010 - 2026) Analysis & Trends
Cryoport (CYRX) has reported Operating Margin for 17 consecutive years, with 20.11% the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Margin fell 258.0% year-over-year to 20.11%; the TTM figure through Mar 2026 stood at 21.44% (up 4793.0% YoY), while the FY2025 annual figure was 20.89%, up 5672.0% from the prior year.
- Operating Margin rose to 20.11% in Q1 2026 per CYRX's latest filing, from 22.07% in the prior quarter.
- Across five years, Operating Margin topped out at 753.46% in Q4 2023 and bottomed at 196.5% in Q2 2024.
- Historically, Operating Margin has averaged 12.26% across 5 years, with a median of 21.23% in 2025.
- Annual changes were most pronounced in 2023 — Operating Margin surged 77174 bps — and 2024, when it plunged 78420 bps.
- Cryoport's Operating Margin stood at 18.28% in 2022, then surged by 4221 bps to 753.46% in 2023, then sank by 104 bps to 30.75% in 2024, then rose by 28 bps to 22.07% in 2025, then rose by 9 bps to 20.11% in 2026.
- Business Quant data shows CYRX's Operating Margin at 20.11% in Q1 2026, 22.07% in Q4 2025, and 22.45% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | United Parcel Service | 87.24 Bn | 82.59 Bn | 19.65 Bn | 4.07% |
| 2 | Fedex | 77.35 Bn | 64.04 Bn | 18.84 Bn | 6.20% |
| 3 | Hunt J B Transport Services | 25.86 Bn | 25.86 Bn | - | 7.42% |
| 4 | Expeditors International Of Washington | 24.43 Bn | 23.40 Bn | 1.09 Bn | 9.98% |
| 5 | C. H. Robinson Worldwide | 17.04 Bn | 16.89 Bn | 1.11 Bn | 5.18% |
| 6 | ZTO Express (Cayman) | 17.03 Bn | 12.62 Bn | 469.01 Mn | 19.16% |
| 7 | Landstar System | 6.19 Bn | 5.84 Bn | 308.86 Mn | 4.62% |
| 8 | GXO Logistics | 5.22 Bn | 4.45 Bn | 508.00 Mn | 2.24% |
| 9 | Pitney Bowes | 2.21 Bn | 1.93 Bn | 296.14 Mn | -19.90% |
| 10 | Cryoport | 842.14 Mn | 445.45 Mn | 22.82 Mn | -20.50% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -20.50% |
| Mar 31, 2026 | -20.11% |
| Dec 31, 2025 | -22.07% |
| Sep 30, 2025 | -22.45% |
| Jun 30, 2025 | -21.23% |
| Mar 31, 2025 | -17.53% |
| Dec 31, 2024 | -30.75% |
| Sep 30, 2024 | -34.94% |
| Jun 30, 2024 | -196.50% |
| Mar 31, 2024 | -46.95% |
| Dec 31, 2023 | 753.46% |
| Sep 30, 2023 | -30.11% |
| Jun 30, 2023 | -32.15% |
| Mar 31, 2023 | -15.99% |
| Dec 31, 2022 | -18.28% |
| Sep 30, 2022 | -12.91% |
| Jun 30, 2022 | -8.18% |
| Mar 31, 2022 | -14.95% |
| Dec 31, 2021 | -14.82% |
| Sep 30, 2021 | -8.07% |