Cryoport (CYRX) Operating Margin (2010 - 2026)
Cryoport (CYRX) reported Operating Margin of 20.11% for Q1 2026, down 258.0% year-over-year from 12.73% in Q1 2025, and down 145.67% quarter-over-quarter from 44.05% in Q4 2025.
Cryoport (CYRX) Operating Margin (2010 - 2026) Analysis & Trends
Cryoport (CYRX) has 17 years of Operating Margin data on file, last reported at 20.11% in Q1 2026.
- Operating Margin for Q1 2026 came in at 20.11%, down 258.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 5.02% (up 221.0% YoY), and the FY2025 annual result was 3.83%, up 1014.0% from the prior year.
- Operating Margin declined to 20.11% in Q1 2026 per CYRX's latest filing, from 44.05% in the prior quarter.
- Over five years, Operating Margin peaked at 209.91% in Q4 2024 and troughed at 376.41% in Q4 2023.
- A 5-year average of 36.16% and a median of 20.11% in 2026 frame the typical range for Operating Margin.
- The sharpest annual moves came in 2023 and 2024: Operating Margin sank 35813 bps in 2023, then surged 58632 bps in 2024.
- A 5-year view of Operating Margin shows it stood at 18.28% in 2022, then tumbled by 1959 bps to 376.41% in 2023, then soared by 156 bps to 209.91% in 2024, then sank by 79 bps to 44.05% in 2025, then plunged by 146 bps to 20.11% in 2026.
- Business Quant data shows CYRX's Operating Margin at 20.11% in Q1 2026, 44.05% in Q4 2025, and 22.45% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | United Parcel Service | 92.26 Bn | 86.49 Bn | 18.44 Bn | 5.98% |
| 2 | Fedex | 78.12 Bn | 66.43 Bn | 20.49 Bn | 5.62% |
| 3 | Hunt J B Transport Services | 26.94 Bn | 26.93 Bn | 2.88 Bn | 6.77% |
| 4 | C. H. Robinson Worldwide | 22.05 Bn | 21.89 Bn | 1.50 Bn | 4.38% |
| 5 | Expeditors International Of Washington | 21.79 Bn | 20.48 Bn | 2.84 Bn | -20.02% |
| 6 | Landstar System | 7.42 Bn | 7.01 Bn | 1.16 Bn | 4.55% |
| 7 | GXO Logistics | 5.58 Bn | 4.83 Bn | 490.00 Mn | 1.18% |
| 8 | ZTO Express (Cayman) | 2.73 Bn | -774.03 Mn | 469.01 Mn | 19.16% |
| 9 | Pitney Bowes | 2.47 Bn | 2.16 Bn | 375.39 Mn | -4.51% |
| 10 | Cryoport | 783.40 Mn | 379.76 Mn | 21.91 Mn | -20.11% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -20.11% |
| Dec 31, 2025 | 44.05% |
| Sep 30, 2025 | -22.45% |
| Jun 30, 2025 | -21.23% |
| Mar 31, 2025 | -17.53% |
| Dec 31, 2024 | 209.91% |
| Sep 30, 2024 | -34.94% |
| Jun 30, 2024 | -196.50% |
| Mar 31, 2024 | -46.95% |
| Dec 31, 2023 | -376.41% |
| Sep 30, 2023 | -30.11% |
| Jun 30, 2023 | -32.15% |
| Mar 31, 2023 | -15.99% |
| Dec 31, 2022 | -18.28% |
| Sep 30, 2022 | -12.91% |
| Jun 30, 2022 | -8.18% |
| Mar 31, 2022 | -14.95% |
| Dec 31, 2021 | -14.82% |
| Sep 30, 2021 | -8.07% |
| Jun 30, 2021 | -6.67% |