Cryoport (CYRX) Net Margin (2010 - 2026)
Cryoport (CYRX) posted Net Margin of -20.94% for Q2 2026, down 256.06 percentage points from 235.11% a year earlier but up 5.30 percentage points from the prior quarter.
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Analysis
Cryoport (CYRX) Net Margin (2010 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Net Margin at Cryoport was -24.34%, down 67.05 percentage points year-over-year; for FY2025, it came in at 39.90%, up 118.21 percentage points from FY2024.
- Annual Net Margin shows a five-year change of +135.24 percentage points (FY2020 to FY2025).
- In prior years, Cryoport's Net Margin was -78.30% in FY2024 (-14.52 pp), -63.79% in FY2023 (-44.68 pp), -19.11% in FY2022 (+108.35 pp) and -127.45% in FY2021 (-32.11 pp).
- Quarterly Net Margin has run from a low of -464.36% in Q4 2021 to a high of 235.11% in Q2 2025 over five years.
- On a year-over-year basis, Net Margin increased in five of the last seven quarters, with an average year-over-year change of +33.87 percentage points.
- The strongest year-over-year quarter for Net Margin in the past five years was Q4 2022, with a gain of 445.42 percentage points; the weakest was Q4 2021, with a drop of 352.98 percentage points.
- According to Business Quant data, Net Margin for the three prior quarters was -26.24% (Q1 2026), -30.02% (Q4 2025) and -20.22% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Union Pacific | 162.83 Bn | 157.35 Bn | - | 29.04% |
| 2 | Csx | 86.94 Bn | 83.15 Bn | - | 25.46% |
| 3 | Canadian Pacific Kansas City | 76.07 Bn | 75.78 Bn | - | 24.59% |
| 4 | United Parcel Service | 70.39 Bn | 47.31 Bn | - | 2.65% |
| 5 | Norfolk Southern | 70.35 Bn | 64.99 Bn | - | 21.18% |
| 6 | Fedex | 68.01 Bn | 33.95 Bn | - | 6.39% |
| 7 | Delta Air Lines | 55.83 Bn | 38.01 Bn | - | 8.12% |
| 8 | Old Dominion Freight Line | 36.82 Bn | 36.08 Bn | - | 22.56% |
| 9 | Ryanair Holdings | 28.96 Bn | 12.97 Bn | 3.13 Bn | 12.26% |
| 10 | Cryoport | 877.23 Mn | -755.62 Mn | 22.82 Mn | -20.94% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -20.94% |
| Mar 31, 2026 | -26.24% |
| Dec 31, 2025 | -30.02% |
| Sep 30, 2025 | -20.22% |
| Jun 30, 2025 | 235.11% |
| Mar 31, 2025 | -34.07% |
| Dec 31, 2024 | -49.88% |
| Sep 30, 2024 | -3.12% |
| Jun 30, 2024 | -201.44% |
| Mar 31, 2024 | -56.03% |
| Sep 30, 2023 | -27.19% |
| Jun 30, 2023 | -35.70% |
| Mar 31, 2023 | -12.06% |
| Dec 31, 2022 | -18.95% |
| Sep 30, 2022 | -12.10% |
| Jun 30, 2022 | -17.42% |
| Mar 31, 2022 | -29.45% |
| Dec 31, 2021 | -464.36% |
| Sep 30, 2021 | -15.04% |
| Jun 30, 2021 | -13.15% |
API Access
Cryoport Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=CYRX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "CYRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=CYRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();