Cryoport (CYRX) EBITDA Margin (2010 - 2026)
Cryoport (CYRX) recorded EBITDA Margin of -7.04% in Q2 2026, down 1.87 percentage points from -5.18% a year earlier and down 0.33 percentage points from the prior quarter.
Cryoport (CYRX) EBITDA Margin (2010 - 2026) Analysis & Trends
On a TTM basis, Cryoport's EBITDA Margin came in at -7.43% as of Jun 30, 2026, down 0.03 percentage points year-over-year; for FY2025, it was -5.16%, up 52.83 percentage points from FY2024.
- Annual EBITDA Margin has a five-year change of +20.43 percentage points (FY2020 to FY2025).
- Across earlier years, EBITDA Margin came in at -57.99% in FY2024 (-14.68 pp), -43.31% in FY2023 (-39.46 pp), -3.85% in FY2022 (-4.94 pp) and 1.09% in FY2021 (+26.68 pp).
- Quarterly EBITDA Margin has ranged from -177.47% in Q2 2024 to 1.10% in Q1 2025 over the past five years.
- On a year-over-year basis, EBITDA Margin rose in five of the last seven quarters, with an average year-over-year change of +29.16 percentage points.
- Peak year-over-year performance for EBITDA Margin in the last five years was a gain of 172.29 percentage points in Q2 2025, against a drop of 157.11 percentage points in Q2 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -6.72% (Q1 2026), -8.09% (Q4 2025) and -7.95% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Union Pacific | 176.45 Bn | 168.70 Bn | - | 49.83% |
| 2 | Csx | 94.58 Bn | 89.81 Bn | - | 49.37% |
| 3 | Canadian Pacific Kansas City | 78.96 Bn | 78.67 Bn | - | 47.81% |
| 4 | United Parcel Service | 75.08 Bn | 52.01 Bn | - | 8.36% |
| 5 | Norfolk Southern | 75.03 Bn | 69.49 Bn | - | 42.91% |
| 6 | Fedex | 71.10 Bn | 37.05 Bn | - | 10.71% |
| 7 | Delta Air Lines | 52.10 Bn | 34.29 Bn | - | 10.54% |
| 8 | Old Dominion Freight Line | 37.86 Bn | 37.12 Bn | - | 35.84% |
| 9 | United Airlines Holdings | 32.71 Bn | -24.98 Bn | - | 12.44% |
| 10 | Cryoport | 901.04 Mn | -731.81 Mn | 22.82 Mn | -6.44% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -6.44% |
| Mar 31, 2026 | -6.10% |
| Dec 31, 2025 | -7.44% |
| Sep 30, 2025 | -7.29% |
| Jun 30, 2025 | -4.49% |
| Mar 31, 2025 | 1.88% |
| Dec 31, 2024 | -10.94% |
| Sep 30, 2024 | -13.39% |
| Jun 30, 2024 | -175.97% |
| Mar 31, 2024 | -25.31% |
| Sep 30, 2023 | -16.66% |
| Jun 30, 2023 | -19.23% |
| Mar 31, 2023 | -4.78% |
| Dec 31, 2022 | -7.04% |
| Sep 30, 2022 | -2.27% |
| Jun 30, 2022 | 1.37% |
| Mar 31, 2022 | -3.46% |
| Dec 31, 2021 | -4.53% |
| Sep 30, 2021 | 1.37% |
| Jun 30, 2021 | 2.48% |
Cryoport EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CYRX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "CYRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CYRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();