Cyclerion Therapeutics (CYCN) Price to Book (2019 - 2025)
Cyclerion Therapeutics (CYCN) posted Price to Book of 0.52 for Q4 2025, down 42.03% on a QoQ basis from 0.89 in Q3 2025, and down 44.24% year-over-year from 0.93 in Q4 2024.
Analysis
Cyclerion Therapeutics (CYCN) Price to Book (2019 - 2025) Analysis & Trends
Cyclerion Therapeutics has reported Price to Book for 7 years, with the latest figure at 0.52 in Q4 2025.
- On a quarterly basis, Price to Book fell 44.24% year-over-year to 0.52 in Q4 2025; TTM through Dec 2025 was 0.52, a 44.24% decrease from a year earlier, with the FY2025 full-year figure at 0.36, down 61.58% from the prior year.
- Price to Book was 0.52 for Q4 2025 at Cyclerion Therapeutics, down from 0.89 in the prior quarter.
- The five-year high for Price to Book was 4.81 in Q1 2023, with the low at 0.52 in Q4 2025.
- Average Price to Book over 5 years is 1.49, with a median of 0.99 recorded in 2022.
- The sharpest annual moves came in 2021 and 2024: Price to Book jumped 218611.06% in 2021, then tumbled 83.25% in 2024.
- Over 5 years, Price to Book stood at 1.55 in 2021, then soared by 76.54% to 2.73 in 2022, then slumped by 73.13% to 0.73 in 2023, then grew by 26.15% to 0.93 in 2024, then sank by 44.24% to 0.52 in 2025.
- The last three Price to Book figures came in at 0.52 (Q4 2025), 0.89 (Q3 2025), and 1.04 (Q2 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Amgen | 206.58 Bn | 192.59 Bn | 7.24 Bn |
| 2 | Gilead Sciences | 180.17 Bn | 176.99 Bn | 6.22 Bn |
| 3 | Vertex Pharmaceuticals | 130.59 Bn | 122.74 Bn | 2.84 Bn |
| 4 | Regeneron Pharmaceuticals | 81.61 Bn | 73.61 Bn | 3.93 Bn |
| 5 | Argenx Se | 60.24 Bn | 55.05 Bn | 1.37 Bn |
| 6 | Moderna | 54.29 Bn | 49.15 Bn | 52.00 Mn |
| 7 | Alnylam Pharmaceuticals | 32.96 Bn | 29.65 Bn | 992.69 Mn |
| 8 | Biogen | 31.94 Bn | 30.66 Bn | 1.96 Bn |
| 9 | Roivant Sciences | 29.38 Bn | 29.38 Bn | 1.16 Mn |
| 10 | Cyclerion Therapeutics | 15.70 Mn | 12.46 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 0.52 |
| Sep 30, 2025 | 0.89 |
| Jun 30, 2025 | 1.04 |
| Mar 31, 2025 | 0.87 |
| Dec 31, 2024 | 0.93 |
| Sep 30, 2024 | 0.80 |
| Jun 30, 2024 | 0.66 |
| Mar 31, 2024 | 0.81 |
| Dec 31, 2023 | 0.73 |
| Sep 30, 2023 | 0.65 |
| Jun 30, 2023 | 1.93 |
| Mar 31, 2023 | 4.81 |
| Dec 31, 2022 | 2.73 |
| Sep 30, 2022 | 2.26 |
| Jun 30, 2022 | 0.94 |
| Mar 31, 2022 | 1.30 |
| Dec 31, 2021 | 1.55 |
| Sep 30, 2021 | 2.36 |
| Jun 30, 2021 | 2.14 |
| Mar 31, 2021 | 1.97 |