Cyclerion Therapeutics CYCN
NASDAQ CYCN
$3.36 -0.85 (-20.19%)
At close: Sep 8, 2026 · 4:00 PM EDT

Cyclerion Therapeutics (CYCN) Price to Book (2019 - 2025)

Cyclerion Therapeutics (CYCN) posted Price to Book of 0.52 for Q4 2025, down 42.03% on a QoQ basis from 0.89 in Q3 2025, and down 44.24% year-over-year from 0.93 in Q4 2024.

Analysis

Cyclerion Therapeutics (CYCN) Price to Book (2019 - 2025) Analysis & Trends

Cyclerion Therapeutics has reported Price to Book for 7 years, with the latest figure at 0.52 in Q4 2025.

  • On a quarterly basis, Price to Book fell 44.24% year-over-year to 0.52 in Q4 2025; TTM through Dec 2025 was 0.52, a 44.24% decrease from a year earlier, with the FY2025 full-year figure at 0.36, down 61.58% from the prior year.
  • Price to Book was 0.52 for Q4 2025 at Cyclerion Therapeutics, down from 0.89 in the prior quarter.
  • The five-year high for Price to Book was 4.81 in Q1 2023, with the low at 0.52 in Q4 2025.
  • Average Price to Book over 5 years is 1.49, with a median of 0.99 recorded in 2022.
  • The sharpest annual moves came in 2021 and 2024: Price to Book jumped 218611.06% in 2021, then tumbled 83.25% in 2024.
  • Over 5 years, Price to Book stood at 1.55 in 2021, then soared by 76.54% to 2.73 in 2022, then slumped by 73.13% to 0.73 in 2023, then grew by 26.15% to 0.93 in 2024, then sank by 44.24% to 0.52 in 2025.
  • The last three Price to Book figures came in at 0.52 (Q4 2025), 0.89 (Q3 2025), and 1.04 (Q2 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Amgen 206.58 Bn 192.59 Bn 7.24 Bn
2 Gilead Sciences 180.17 Bn 176.99 Bn 6.22 Bn
3 Vertex Pharmaceuticals 130.59 Bn 122.74 Bn 2.84 Bn
4 Regeneron Pharmaceuticals 81.61 Bn 73.61 Bn 3.93 Bn
5 Argenx Se 60.24 Bn 55.05 Bn 1.37 Bn
6 Moderna 54.29 Bn 49.15 Bn 52.00 Mn
7 Alnylam Pharmaceuticals 32.96 Bn 29.65 Bn 992.69 Mn
8 Biogen 31.94 Bn 30.66 Bn 1.96 Bn
9 Roivant Sciences 29.38 Bn 29.38 Bn 1.16 Mn
10 Cyclerion Therapeutics 15.70 Mn 12.46 Mn -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 0.52
Sep 30, 2025 0.89
Jun 30, 2025 1.04
Mar 31, 2025 0.87
Dec 31, 2024 0.93
Sep 30, 2024 0.80
Jun 30, 2024 0.66
Mar 31, 2024 0.81
Dec 31, 2023 0.73
Sep 30, 2023 0.65
Jun 30, 2023 1.93
Mar 31, 2023 4.81
Dec 31, 2022 2.73
Sep 30, 2022 2.26
Jun 30, 2022 0.94
Mar 31, 2022 1.30
Dec 31, 2021 1.55
Sep 30, 2021 2.36
Jun 30, 2021 2.14
Mar 31, 2021 1.97