Growth Metrics

CRISPR Therapeutics AG (CRSP) Operating Income (2016 - 2025)

CRISPR Therapeutics AG's Operating Income history spans 11 years, with the latest figure at -$154.8 million for Q4 2025.

  • For Q4 2025, Operating Income fell 139.62% year-over-year to -$154.8 million; the TTM value through Dec 2025 reached -$664.6 million, down 42.44%, while the annual FY2025 figure was -$664.6 million, 42.44% down from the prior year.
  • Operating Income for Q4 2025 was -$154.8 million at CRISPR Therapeutics AG, down from -$132.1 million in the prior quarter.
  • Across five years, Operating Income topped out at $762.6 million in Q2 2021 and bottomed at -$229.3 million in Q2 2025.
  • The 5-year median for Operating Income is -$132.2 million (2023), against an average of -$82.7 million.
  • The largest annual shift saw Operating Income surged 1045.13% in 2021 before it crashed 192.82% in 2024.
  • A 5-year view of Operating Income shows it stood at -$145.7 million in 2021, then grew by 9.72% to -$131.5 million in 2022, then surged by 152.9% to $69.6 million in 2023, then plummeted by 192.82% to -$64.6 million in 2024, then plummeted by 139.62% to -$154.8 million in 2025.
  • Per Business Quant, the three most recent readings for CRSP's Operating Income are -$154.8 million (Q4 2025), -$132.1 million (Q3 2025), and -$229.3 million (Q2 2025).