CRISPR Therapeutics AG (CRSP) EBITDA (2015 - 2026)

CRISPR Therapeutics AG's (CRSP) quarterly EBITDA came in at -$129.7 million in Q1 2026, up 3.0% year-on-year from -$125.9 million in Q1 2025, and up 0.83% quarter-over-quarter from -$130.8 million in Q4 2025.

CRISPR Therapeutics AG (CRSP) EBITDA (2015 - 2026) Analysis & Trends

CRISPR Therapeutics AG has disclosed EBITDA across 12 years of filings, most recently posting -$129.7 million for Q1 2026.

  • EBITDA for Q1 2026 came in at -$129.7 million, up 3.0% year-over-year; the trailing twelve-month figure through Mar 2026 was -$574.6 million (down 51.23% YoY), and the FY2025 annual result was -$578.6 million, down 57.95% from the prior year.
  • EBITDA came in at -$129.7 million for Q1 2026 at CRISPR Therapeutics AG, up from -$130.8 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $98.1 million in Q4 2023 to a low of -$208.6 million in Q2 2025.
  • The 5-year median for EBITDA is -$120.1 million (2024), against an average of -$110.1 million.
  • Across the five-year window, EBITDA jumped 194.32% in 2023 and plunged 184.08% in 2025, its largest moves.
  • CRISPR Therapeutics AG's EBITDA stood at -$104.0 million in 2022, then surged by 194.32% to $98.1 million in 2023, then slumped by 146.95% to -$46.0 million in 2024, then tumbled by 184.08% to -$130.8 million in 2025, then climbed by 0.83% to -$129.7 million in 2026.
  • The last three EBITDA figures came in at -$129.7 million (Q1 2026), -$130.8 million (Q4 2025), and -$105.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 CRISPR Therapeutics AG 5.21 Bn 2.76 Bn - -129.69 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -129.69 Mn
Dec 31, 2025 -130.78 Mn
Sep 30, 2025 -105.50 Mn
Jun 30, 2025 -208.64 Mn
Mar 31, 2025 -133.70 Mn
Dec 31, 2024 -46.04 Mn
Sep 30, 2024 -72.50 Mn
Jun 30, 2024 -127.74 Mn
Mar 31, 2024 -120.06 Mn
Dec 31, 2023 98.06 Mn
Sep 30, 2023 -110.04 Mn
Jun 30, 2023 -77.26 Mn
Mar 31, 2023 -46.81 Mn
Dec 31, 2022 -103.96 Mn
Sep 30, 2022 -176.47 Mn
Jun 30, 2022 -189.28 Mn
Mar 31, 2022 -191.04 Mn
Dec 31, 2021 -145.55 Mn
Sep 30, 2021 -127.29 Mn
Jun 30, 2021 759.06 Mn