Caribou Biosciences (CRBU) Net Margin (2020 - 2026)
Caribou Biosciences (CRBU) recorded Net Margin of -1619.88% in Q2 2026, up 408.54 percentage points from -2028.42% a year earlier but down 573.36 percentage points from the prior quarter.
Caribou Biosciences (CRBU) Net Margin (2020 - 2026) Analysis & Trends
On a TTM basis, Caribou Biosciences' Net Margin came in at -1030.42% as of Jun 30, 2026, up 770.51 percentage points year-over-year; for FY2025, it came in at -1327.40%, up 164.54 percentage points from FY2024.
- Annual Net Margin has a five-year change of -1049.85 percentage points (FY2020 to FY2025).
- Across earlier years, Net Margin came in at -1491.95% in FY2024 (-1195.89 pp), -296.05% in FY2023 (+421.74 pp), -717.79% in FY2022 (-20.53 pp) and -697.26% in FY2021 (-419.71 pp).
- Quarterly Net Margin has ranged from -2028.42% in Q2 2025 to -42.27% in Q3 2023 over the past five years.
- On a year-over-year basis, Net Margin has increased for four consecutive quarters, with an average year-over-year change of -99.24 percentage points over the last eight quarters.
- Peak year-over-year performance for Net Margin in the last five years was a gain of 1036.60 percentage points in Q4 2025, against a drop of 1671.37 percentage points in Q3 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -1046.52% (Q1 2026), -672.11% (Q4 2025) and -1253.32% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 32.99% |
| 10 | Caribou Biosciences | 131.43 Mn | -385.10 Mn | - | -1,619.88% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,619.88% |
| Mar 31, 2026 | -1,046.52% |
| Dec 31, 2025 | -672.11% |
| Sep 30, 2025 | -1,253.32% |
| Jun 30, 2025 | -2,028.42% |
| Mar 31, 2025 | -1,699.58% |
| Dec 31, 2024 | -1,708.71% |
| Sep 30, 2024 | -1,713.64% |
| Jun 30, 2024 | -1,088.25% |
| Mar 31, 2024 | -1,697.57% |
| Dec 31, 2023 | -969.79% |
| Sep 30, 2023 | -42.27% |
| Jun 30, 2023 | -786.13% |
| Mar 31, 2023 | -800.80% |
| Dec 31, 2022 | -731.01% |
| Sep 30, 2022 | -806.75% |
| Jun 30, 2022 | -636.86% |
| Mar 31, 2022 | -716.52% |
| Dec 31, 2021 | -722.12% |
| Sep 30, 2021 | -527.38% |
Caribou Biosciences Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=CRBU&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "CRBU", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=CRBU&period=max&api_key=YOUR_API_KEY");
const data = await res.json();