Growth Metrics

Caribou Biosciences (CRBU) EBITDA (2020 - 2026)

Caribou Biosciences (CRBU) reported EBITDA of -$25.2 million for Q1 2026, up 37.1% year-over-year from -$18.4 million in Q1 2025, and up 4.79% on a QoQ basis from -$26.5 million in Q4 2025.

Caribou Biosciences (CRBU) has 7 years of EBITDA data on file, last reported at -$25.2 million in Q1 2026.

  • Quarterly EBITDA rose 37.1% year-over-year to -$25.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$133.4 million (up 9.48% YoY) and the FY2025 annual result came in at -$148.3 million, changed 0.41% from the prior year.
  • EBITDA advanced to -$25.2 million in Q1 2026 per CRBU's latest filing, from -$26.5 million in the prior quarter.
  • Across five years, EBITDA topped out at -$9.8 million in Q3 2023 and bottomed at -$54.2 million in Q2 2025.
  • The 5-year median for EBITDA is -$27.5 million (2025), against an average of -$30.8 million.
  • The widest annual swing landed in 2023, when EBITDA soared 63.67%; it then slumped 240.98% in 2024.
  • Tracing CRBU's EBITDA over 5 years: stood at -$26.5 million in 2022, then decreased by 26.53% to -$33.5 million in 2023, then dropped by 7.55% to -$36.0 million in 2024, then rose by 26.5% to -$26.5 million in 2025, then gained by 4.79% to -$25.2 million in 2026.
  • Per Business Quant, the three latest CRBU EBITDA figures stand at -$25.2 million (Q1 2026), -$26.5 million (Q4 2025), and -$27.5 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Caribou Biosciences 232.46 Mn 114.84 Mn - -25.21 Mn

Historic Data

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DateValue
Mar 31, 2026 -25.21 Mn
Dec 31, 2025 -26.48 Mn
Sep 30, 2025 -27.50 Mn
Jun 30, 2025 -54.23 Mn
Mar 31, 2025 -40.08 Mn
Dec 31, 2024 -36.02 Mn
Sep 30, 2024 -33.58 Mn
Jun 30, 2024 -37.69 Mn
Mar 31, 2024 -41.59 Mn
Dec 31, 2023 -33.49 Mn
Sep 30, 2023 -9.85 Mn
Jun 30, 2023 -29.93 Mn
Mar 31, 2023 -27.26 Mn
Dec 31, 2022 -26.47 Mn
Sep 30, 2022 -27.10 Mn
Jun 30, 2022 -27.19 Mn
Mar 31, 2022 -20.04 Mn
Dec 31, 2021 -18.61 Mn
Sep 30, 2021 -20.97 Mn
Jun 30, 2021 -14.31 Mn
Mar 31, 2021 -13.16 Mn
Dec 31, 2020 -15.21 Mn
Sep 30, 2020 -8.23 Mn
Jun 30, 2020 -2.26 Mn
Mar 31, 2020 -10.43 Mn