Centessa Pharmaceuticals (CNTA) Operating Income (2020 - 2026)

Centessa Pharmaceuticals (CNTA) reported Operating Income of -$79.8 million for Q1 2026, down 159.2% year-over-year from $134.8 million in Q1 2025, and down 16.5% on a QoQ basis from -$68.5 million in Q4 2025.

Centessa Pharmaceuticals (CNTA) has 7 years of Operating Income data on file, last reported at -$79.8 million in Q1 2026.

  • Quarterly Operating Income fell 159.2% year-over-year to -$79.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$256.7 million (down 31.14% YoY) and the FY2025 annual result came in at -$207.7 million, down 3.3% from the prior year.
  • Operating Income retreated to -$79.8 million in Q1 2026 per CNTA's latest filing, from -$68.5 million in the prior quarter.
  • Across five years, Operating Income topped out at -$30.8 million in Q1 2025 and bottomed at -$79.8 million in Q1 2026.
  • The 5-year median for Operating Income is -$48.9 million (2023), against an average of -$51.3 million.
  • The widest annual swing landed in 2022, when Operating Income jumped 77.47%; it then tumbled 159.2% in 2026.
  • Tracing CNTA's Operating Income over 5 years: stood at -$41.6 million in 2022, then advanced by 15.44% to -$35.2 million in 2023, then plunged by 112.01% to -$74.6 million in 2024, then grew by 8.19% to -$68.5 million in 2025, then declined by 16.5% to -$79.8 million in 2026.
  • Per Business Quant, the three latest CNTA Operating Income figures stand at -$79.8 million (Q1 2026), -$68.5 million (Q4 2025), and -$53.8 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Centessa Pharmaceuticals 6.12 Bn 6.12 Bn - -79.77 Mn

Historic Data

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DateValue
Mar 31, 2026 -79.77 Mn
Dec 31, 2025 -68.47 Mn
Sep 30, 2025 -53.79 Mn
Jun 30, 2025 -54.65 Mn
Mar 31, 2025 -30.78 Mn
Dec 31, 2024 -74.58 Mn
Sep 30, 2024 -46.41 Mn
Jun 30, 2024 -43.98 Mn
Mar 31, 2024 -36.09 Mn
Dec 31, 2023 -35.18 Mn
Sep 30, 2023 -40.21 Mn
Jun 30, 2023 -47.02 Mn
Mar 31, 2023 -48.88 Mn
Dec 31, 2022 -41.60 Mn
Sep 30, 2022 -49.03 Mn
Jun 30, 2022 -68.41 Mn
Mar 31, 2022 -53.22 Mn
Dec 31, 2021 -58.29 Mn
Sep 30, 2021 -38.31 Mn
Jun 30, 2021 -41.29 Mn
Mar 31, 2021 -236.19 Mn
Dec 31, 2020 -3.01 Mn
Sep 30, 2020 -2.12 Mn
Jun 30, 2020 -2.13 Mn