Centessa Pharmaceuticals plc (CNTA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

134,073,436Shares Outstanding

41,197,273Shares held by institutions

$1,092,139,707Value of institutional holdings

96.55%Institutional ownership %

3.21%Shares Changed QoQ

126No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Centessa Pharmaceuticals plc (NASDAQ:CNTA) currently has 126 active institutional owners and shareholders as of today (September 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

The collective stake of institutional investors in Centessa Pharmaceuticals moved to 96.5% in September 2025, a shift up from the 92.6% reported for June 2025.
Quarterly data indicates a 3.21% shift in institutional share volume, and the annual owner count reflects an increase of 23.53%.
Of these 126 institutional investors, 54 increased their holdings in Centessa Pharmaceuticals, while 56 of them reduced positions, and 16 investors maintained their exposure.
The total number of shares held by institutions in Centessa Pharmaceuticals increased to 129.44Mn as of September 2025, a net change of up by 4.02Mn shares quarter on quarter, and up 20.94Mn shares year over year.
Medicxi Ventures Management (Jersey) Ltd continues to be the largest institutional holder of Centessa Pharmaceuticals as of September 30, 2025, with a position of 19.96Mn shares, representing 14.89% of the company's outstanding stock.
Among the most significant buyers of Centessa Pharmaceuticals during September 2025 were Avoro Capital Advisors LLC (5.81Mn), FMR LLC (2.45Mn), PERCEPTIVE ADVISORS LLC (1.95Mn), FEDERATED HERMES, INC. (1.75Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (1.63Mn).
Leading sellers of Centessa Pharmaceuticals stock in September 2025 included EcoR1 Capital, LLC (2.67Mn), Point72 Asset Management, L.P. (1.52Mn), JANUS HENDERSON GROUP PLC (1.12Mn), PRICE T ROWE ASSOCIATES INC /MD/ (1.10Mn), MILLENNIUM MANAGEMENT LLC (768.82K).
The top 10 institutional holders of Centessa Pharmaceuticals for the quarter ending September 2025 included Medicxi Ventures Management (Jersey) Ltd (19.96Mn), Avoro Capital Advisors LLC (10.81Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (10.04Mn), Index Venture Life Associates VI Ltd (9.96Mn), GENERAL ATLANTIC, L.P. (9.68Mn), FMR LLC (6.28Mn), JANUS HENDERSON GROUP PLC (5.41Mn), PRICE T ROWE ASSOCIATES INC /MD/ (4.80Mn), FARALLON CAPITAL MANAGEMENT LLC (4.33Mn), First Light Asset Management, LLC (3.64Mn).

126 Institutional Holders

41,197,273 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Medicxi Ventures Management (Jersey) Ltd	30 Sep, 2025	19,963,157	0	0.00%	$484,106,557.00
Avoro Capital Advisors LLC	30 Sep, 2025	10,808,080	5,808,080	116.16%	$262,095,940.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	30 Sep, 2025	10,035,000	1,632,000	19.42%	$243,348,750.00
Index Venture Life Associates VI Ltd	30 Sep, 2025	9,961,789	0	0.00%	$241,573,383.00
GENERAL ATLANTIC, L.P.	30 Sep, 2025	9,681,818	0	0.00%	$234,784,087.00
FMR LLC	30 Sep, 2025	6,277,243	2,451,049	64.06%	$152,223,143.00
JANUS HENDERSON GROUP PLC	30 Sep, 2025	5,408,199	-1,124,569	-17.21%	$131,075,198.00
PRICE T ROWE ASSOCIATES INC /MD/	30 Sep, 2025	4,804,056	-1,103,936	-18.69%	$116,499.00
FARALLON CAPITAL MANAGEMENT LLC	30 Sep, 2025	4,331,318	-198,000	-4.37%	$105,034,462.00
First Light Asset Management, LLC	30 Sep, 2025	3,635,816	-657,595	-15.32%	$88,168,538.00
Siren, L.L.C.	30 Sep, 2025	3,227,517	-232,512	-6.72%	$78,267,287.00
TCG Crossover Management, LLC	30 Sep, 2025	3,136,480	245,664	8.50%	$76,059,640.00
PERCEPTIVE ADVISORS LLC	30 Sep, 2025	3,100,902	1,953,967	170.36%	$75,196,874.00
Commodore Capital LP	30 Sep, 2025	2,850,000	-448,289	-13.59%	$69,112,500.00
FRANKLIN RESOURCES INC	30 Sep, 2025	2,558,414	14,875	0.58%	$62,041,541.00
RTW INVESTMENTS, LP	30 Sep, 2025	2,291,747	761,911	49.80%	$55,574,865.00
Cormorant Asset Management, LP	30 Sep, 2025	1,925,000	-161,600	-7.74%	$46,681,250.00
FEDERATED HERMES, INC.	30 Sep, 2025	1,749,650	1,749,650	0.00%	$42,429,013.00
Foresite Capital Management VI LLC	30 Sep, 2025	1,314,019	60,640	4.84%	$31,864,961.00
MORGAN STANLEY	30 Sep, 2025	1,124,445	-669,026	-37.30%	$27,267,792.00

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Centessa Pharmaceuticals plc (CNTA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

126 Institutional Holders

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