Clene (CLNN) Operating Income (2020 - 2025)

Clene's Operating Income history runs 6 years deep, the most recent figure standing at -$7.5 million for Q4 2025.

• On a quarterly basis, Operating Income rose 13.61% year-over-year to -$7.5 million in Q4 2025; TTM through Dec 2025 was -$23.0 million, a 30.4% increase from a year earlier, with the FY2025 full-year figure at -$23.1 million, up 30.26% from the prior year.
• Operating Income declined to -$7.5 million in Q4 2025 per CLNN's latest filing, from -$5.6 million in the prior quarter.
• Across five years, Operating Income topped out at -$4.1 million in Q1 2025 and bottomed at -$14.1 million in Q4 2021.
• The 5-year median for Operating Income is -$9.8 million (2022), against an average of -$9.7 million.
• Across the five-year window, Operating Income plunged 202.57% in 2021 and surged 55.7% in 2025, its largest moves.
• Year by year, Operating Income stood at -$14.1 million in 2021, then increased by 16.97% to -$11.7 million in 2022, then grew by 15.27% to -$9.9 million in 2023, then rose by 12.42% to -$8.7 million in 2024, then climbed by 13.61% to -$7.5 million in 2025.
• Per Business Quant, the three latest CLNN Operating Income figures stand at -$7.5 million (Q4 2025), -$5.6 million (Q3 2025), and -$5.9 million (Q2 2025).