Clene (CLNN) EBITDA (2020 - 2025)

Clene's EBITDA history runs 6 years deep, the most recent figure standing at -$9.2 million for Q4 2025.

• In Q4 2025, EBITDA rose 32.82% year-over-year to -$9.2 million; the TTM figure through Dec 2025 stood at -$26.1 million (up 34.04% YoY), while the FY2025 annual figure was -$26.1 million, up 34.04% from the prior year.
• EBITDA was -$9.2 million for Q4 2025 at Clene, down from -$8.8 million in the prior quarter.
• In the past five years, EBITDA ranged from a high of $28.9 million in Q3 2021 to a low of -$39.7 million in Q1 2021.
• Historically, EBITDA has averaged -$7.7 million across 5 years, with a median of -$8.4 million in 2024.
• The sharpest annual moves came in 2021 and 2023: EBITDA jumped 380.36% in 2021, then plunged 980.88% in 2023.
• A 5-year view of EBITDA shows it stood at $4.5 million in 2021, then slumped by 120.9% to -$931000.0 in 2022, then slumped by 980.88% to -$10.1 million in 2023, then plunged by 36.15% to -$13.7 million in 2024, then soared by 32.82% to -$9.2 million in 2025.
• The last three EBITDA figures came in at -$9.2 million (Q4 2025), -$8.8 million (Q3 2025), and -$7.4 million (Q2 2025), per Business Quant data.