Celldex Therapeutics (CLDX) Operating Income (2010 - 2026)

Celldex Therapeutics' (CLDX) quarterly Operating Income came in at -$84.4 million in Q1 2026, down 34.58% year-on-year from -$129.1 million in Q1 2025, and up 3.12% quarter-over-quarter from -$87.2 million in Q4 2025.

Celldex Therapeutics (CLDX) Operating Income (2010 - 2026) Analysis & Trends

Celldex Therapeutics' Operating Income history runs 17 years deep, the most recent figure standing at -$84.4 million for Q1 2026.

  • On a quarterly basis, Operating Income fell 34.58% year-over-year to -$84.4 million in Q1 2026; TTM through Mar 2026 was -$309.1 million, a 42.29% decrease from a year earlier, with the FY2025 full-year figure at -$287.4 million, down 47.31% from the prior year.
  • Operating Income improved to -$84.4 million in Q1 2026 per CLDX's latest filing, from -$87.2 million in the prior quarter.
  • Across five years, Operating Income topped out at -$23.3 million in Q1 2022 and bottomed at -$87.2 million in Q4 2025.
  • The 5-year median for Operating Income is -$46.3 million (2024), against an average of -$49.2 million.
  • Across the five-year window, Operating Income tumbled 170.8% in 2022 and rose 8.77% in 2023, its largest moves.
  • Year by year, Operating Income stood at -$27.9 million in 2022, then plunged by 70.8% to -$47.6 million in 2023, then decreased by 17.64% to -$56.0 million in 2024, then sank by 55.56% to -$87.2 million in 2025, then gained by 3.12% to -$84.4 million in 2026.
  • Per Business Quant, the three latest CLDX Operating Income figures stand at -$84.4 million (Q1 2026), -$87.2 million (Q4 2025), and -$73.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Celldex Therapeutics 1.72 Mn 1.72 Mn -1.44 Mn -84.44 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -84.44 Mn
Dec 31, 2025 -87.15 Mn
Sep 30, 2025 -73.62 Mn
Jun 30, 2025 -63.86 Mn
Mar 31, 2025 -62.74 Mn
Dec 31, 2024 -56.03 Mn
Sep 30, 2024 -52.13 Mn
Jun 30, 2024 -46.32 Mn
Mar 31, 2024 -40.61 Mn
Dec 31, 2023 -47.63 Mn
Sep 30, 2023 -41.24 Mn
Jun 30, 2023 -33.21 Mn
Mar 31, 2023 -32.47 Mn
Dec 31, 2022 -27.89 Mn
Sep 30, 2022 -27.70 Mn
Jun 30, 2022 -36.40 Mn
Mar 31, 2022 -23.26 Mn
Dec 31, 2021 -20.34 Mn
Sep 30, 2021 -20.82 Mn
Jun 30, 2021 -13.44 Mn