Celldex Therapeutics (CLDX) Operating Income (2010 - 2026)

Celldex Therapeutics (CLDX) recorded quarterly Operating Income of -$84.4 million in Q1 2026, up 3.12% quarter-over-quarter from -$87.2 million in Q4 2025, and down 34.58% on a YoY basis from -$129.1 million in Q1 2025.

Celldex Therapeutics (CLDX) Operating Income (2010 - 2026) Analysis & Trends

Celldex Therapeutics' Operating Income history runs 17 years deep, the most recent figure standing at -$84.4 million for Q1 2026.

  • In Q1 2026, Operating Income fell 34.58% year-over-year to -$84.4 million; the TTM figure through Mar 2026 stood at -$309.1 million (down 42.29% YoY), while the FY2025 annual figure was -$287.4 million, down 47.31% from the prior year.
  • Operating Income was -$84.4 million for Q1 2026 at Celldex Therapeutics, up from -$87.2 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$23.3 million in Q1 2022 to a low of -$87.2 million in Q4 2025.
  • Historically, Operating Income has averaged -$49.2 million across 5 years, with a median of -$46.3 million in 2024.
  • The sharpest annual moves came in 2022 and 2023: Operating Income plunged 177.36% in 2022, then grew 8.77% in 2023.
  • A 5-year view of Operating Income shows it stood at -$27.9 million in 2022, then slumped by 70.8% to -$47.6 million in 2023, then decreased by 17.64% to -$56.0 million in 2024, then tumbled by 55.56% to -$87.2 million in 2025, then gained by 3.12% to -$84.4 million in 2026.
  • The last three Operating Income figures came in at -$84.4 million (Q1 2026), -$87.2 million (Q4 2025), and -$73.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Celldex Therapeutics 2.16 Bn 2.16 Bn -1.44 Mn -84.44 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -84.44 Mn
Dec 31, 2025 -87.15 Mn
Sep 30, 2025 -73.62 Mn
Jun 30, 2025 -63.86 Mn
Mar 31, 2025 -62.74 Mn
Dec 31, 2024 -56.03 Mn
Sep 30, 2024 -52.13 Mn
Jun 30, 2024 -46.32 Mn
Mar 31, 2024 -40.61 Mn
Dec 31, 2023 -47.63 Mn
Sep 30, 2023 -41.24 Mn
Jun 30, 2023 -33.21 Mn
Mar 31, 2023 -32.47 Mn
Dec 31, 2022 -27.89 Mn
Sep 30, 2022 -27.70 Mn
Jun 30, 2022 -36.40 Mn
Mar 31, 2022 -23.26 Mn
Dec 31, 2021 36.05 Mn
Sep 30, 2021 -20.82 Mn
Jun 30, 2021 -13.44 Mn