Celcuity (CELC) EBITDA (2016 - 2025)
Celcuity (CELC) posted EBITDA of -$49.2 million for Q4 2025, down 14.82% on a QoQ basis from -$42.8 million in Q3 2025, and down 35.06% year-over-year from -$75.8 million in Q4 2024.
Celcuity (CELC) EBITDA (2016 - 2025) Analysis & Trends
Celcuity's EBITDA history runs 10 years deep, the most recent figure standing at -$49.2 million for Q4 2025.
- Quarterly EBITDA fell 35.06% year-over-year to -$49.2 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$172.2 million (down 52.02% YoY) and the FY2025 annual result came in at -$172.2 million, down 52.02% from the prior year.
- EBITDA was -$49.2 million for Q4 2025 at Celcuity, down from -$42.8 million in the prior quarter.
- Across five years, EBITDA topped out at -$2.8 million in Q1 2021 and bottomed at -$49.2 million in Q4 2025.
- A 5-year average of -$21.0 million and a median of -$17.0 million in 2023 frame the typical range for EBITDA.
- Annual changes were most pronounced in 2021 — EBITDA plunged 516.25% — and 2022, when it increased 29.63%.
- Celcuity's EBITDA stood at -$6.3 million in 2021, then sank by 84.14% to -$11.6 million in 2022, then slumped by 69.51% to -$19.7 million in 2023, then slumped by 84.65% to -$36.4 million in 2024, then slumped by 35.06% to -$49.2 million in 2025.
- Business Quant data shows CELC's EBITDA at -$49.2 million in Q4 2025, -$42.8 million in Q3 2025, and -$44.0 million in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Celcuity | 4.13 Bn | 4.13 Bn | - | -49.20 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -49.20 Mn |
| Sep 30, 2025 | -42.85 Mn |
| Jun 30, 2025 | -44.01 Mn |
| Mar 31, 2025 | -36.13 Mn |
| Dec 31, 2024 | -36.43 Mn |
| Sep 30, 2024 | -30.06 Mn |
| Jun 30, 2024 | -24.28 Mn |
| Mar 31, 2024 | -22.49 Mn |
| Dec 31, 2023 | -19.73 Mn |
| Sep 30, 2023 | -18.90 Mn |
| Jun 30, 2023 | -15.06 Mn |
| Mar 31, 2023 | -12.55 Mn |
| Dec 31, 2022 | -11.64 Mn |
| Sep 30, 2022 | -10.64 Mn |
| Jun 30, 2022 | -9.60 Mn |
| Mar 31, 2022 | -7.51 Mn |
| Dec 31, 2021 | -6.32 Mn |
| Sep 30, 2021 | -5.60 Mn |
| Jun 30, 2021 | -13.64 Mn |
| Mar 31, 2021 | -2.79 Mn |