Growth Metrics

Codexis (CDXS) Operating Margin (2016 - 2025)

Codexis has reported Operating Margin over the past 16 years, most recently at 27.13% for Q4 2025.

  • Quarterly results put Operating Margin at 27.13% for Q4 2025, up 6134.0% from a year ago — trailing twelve months through Dec 2025 was 59.3% (up 3931.0% YoY), and the annual figure for FY2025 was 59.3%, up 3931.0%.
  • Operating Margin for Q4 2025 was 27.13% at Codexis, up from 220.31% in the prior quarter.
  • Over the last five years, Operating Margin for CDXS hit a ceiling of 27.13% in Q4 2025 and a floor of 345.59% in Q3 2023.
  • Median Operating Margin over the past 5 years was 58.85% (2021), compared with a mean of 103.83%.
  • Biggest five-year swings in Operating Margin: plummeted -31473bps in 2023 and later soared 21657bps in 2024.
  • Codexis' Operating Margin stood at 42.39% in 2021, then tumbled by -58bps to 66.92% in 2022, then soared by 108bps to 5.62% in 2023, then tumbled by -709bps to 34.21% in 2024, then skyrocketed by 179bps to 27.13% in 2025.
  • The last three reported values for Operating Margin were 27.13% (Q4 2025), 220.31% (Q3 2025), and 83.91% (Q2 2025) per Business Quant data.