Codexis (CDXS) Operating Margin (2010 - 2026)
Codexis (CDXS) posted quarterly Operating Margin of 52.75% for Q1 2026, up 21884.0% year-over-year from N/an in Q1 2025, and down 294.4% quarter-over-quarter from 27.13% in Q4 2025.
Codexis (CDXS) Operating Margin (2010 - 2026) Analysis & Trends
Codexis' Operating Margin history runs 17 years deep, the most recent figure standing at 52.75% for Q1 2026.
- In Q1 2026, Operating Margin rose 21884.0% year-over-year to 52.75%; the TTM figure through Mar 2026 stood at 37.51% (up 9722.0% YoY), while the FY2025 annual figure was 59.3%, up 3931.0% from the prior year.
- Operating Margin for Q1 2026 stood at 52.75%, down from 27.13% in the prior quarter.
- The five-year high for Operating Margin was 27.13% in Q4 2025, with the low at 345.59% in Q3 2023.
- The 5-year median for Operating Margin is 69.63% (2024), against an average of 118.96%.
- The sharpest annual moves came in 2023 and 2026: Operating Margin plunged 31473 bps in 2023, then surged 21884 bps in 2026.
- Codexis' Operating Margin stood at 66.92% in 2022, then jumped by 108 bps to 5.62% in 2023, then sank by 709 bps to 34.21% in 2024, then surged by 179 bps to 27.13% in 2025, then plunged by 294 bps to 52.75% in 2026.
- Business Quant data shows CDXS's Operating Margin at 52.75% in Q1 2026, 27.13% in Q4 2025, and 220.31% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | -562.07% |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 19.06% |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 17.93% |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | -0.36% |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 19.75% |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | -35.57% |
| 10 | Codexis | 143.86 Mn | 88.95 Mn | 11.40 Mn | -75.29% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -75.29% |
| Mar 31, 2026 | -52.75% |
| Dec 31, 2025 | 27.13% |
| Sep 30, 2025 | -220.31% |
| Jun 30, 2025 | -83.91% |
| Mar 31, 2025 | -271.59% |
| Dec 31, 2024 | -34.21% |
| Sep 30, 2024 | -129.02% |
| Jun 30, 2024 | -284.90% |
| Mar 31, 2024 | -69.63% |
| Dec 31, 2023 | 5.62% |
| Sep 30, 2023 | -345.59% |
| Jun 30, 2023 | -252.52% |
| Mar 31, 2023 | -182.29% |
| Dec 31, 2022 | -66.92% |
| Sep 30, 2022 | -30.86% |
| Jun 30, 2022 | -6.79% |
| Mar 31, 2022 | -23.73% |
| Dec 31, 2021 | -42.39% |
| Sep 30, 2021 | 3.62% |