Codexis (CDXS) Gross Margin (2010 - 2026)
Codexis (CDXS) posted quarterly Gross Margin of 86.46% for Q1 2026, up 2268.0% year-over-year from 3.65% in Q1 2025, and down 8.75% quarter-over-quarter from 94.75% in Q4 2025.
Codexis (CDXS) Gross Margin (2010 - 2026) Analysis & Trends
Codexis' Gross Margin history runs 17 years deep, the most recent figure standing at 86.46% for Q1 2026.
- In Q1 2026, Gross Margin rose 2268.0% year-over-year to 86.46%; the TTM figure through Mar 2026 stood at 88.9% (up 1733.0% YoY), while the FY2025 annual figure was 86.73%, up 1418.0% from the prior year.
- Gross Margin for Q1 2026 stood at 86.46%, down from 94.75% in the prior quarter.
- The five-year high for Gross Margin was 94.75% in Q4 2025, with the low at 36.44% in Q2 2023.
- The 5-year median for Gross Margin is 71.34% (2025), against an average of 69.16%.
- The sharpest annual moves came in 2023 and 2024: Gross Margin plunged 3422 bps in 2023, then surged 4021 bps in 2024.
- Codexis' Gross Margin stood at 57.29% in 2022, then declined by 25 bps to 42.76% in 2023, then surged by 94 bps to 82.97% in 2024, then grew by 14 bps to 94.75% in 2025, then declined by 9 bps to 86.46% in 2026.
- Business Quant data shows CDXS's Gross Margin at 86.46% in Q1 2026, 94.75% in Q4 2025, and 71.34% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.13 Bn | 131.28 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 85.77 Bn | 77.77 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 64.64 Bn | 59.46 Bn | 1.37 Bn | 90.43% |
| 4 | Moderna | 58.29 Bn | 53.16 Bn | 52.00 Mn | 35.86% |
| 5 | BeOne Medicines | 41.92 Bn | 36.82 Bn | 1.53 Bn | 89.76% |
| 6 | Alnylam Pharmaceuticals | 31.58 Bn | 28.28 Bn | 992.69 Mn | 76.90% |
| 7 | BioNTech SE | 28.12 Bn | 9.73 Bn | 668.28 Mn | 63.27% |
| 8 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn | 84.20% |
| 9 | Royalty Pharma | 27.27 Bn | 26.43 Bn | - | - |
| 10 | Codexis | 152.06 Mn | 97.14 Mn | 11.40 Mn | 76.45% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 76.45% |
| Mar 31, 2026 | 86.46% |
| Dec 31, 2025 | 94.75% |
| Sep 30, 2025 | 71.34% |
| Jun 30, 2025 | 86.31% |
| Mar 31, 2025 | 63.78% |
| Dec 31, 2024 | 82.97% |
| Sep 30, 2024 | 66.36% |
| Jun 30, 2024 | 56.61% |
| Mar 31, 2024 | 71.56% |
| Dec 31, 2023 | 42.76% |
| Sep 30, 2023 | 75.76% |
| Jun 30, 2023 | 36.44% |
| Mar 31, 2023 | 65.17% |
| Dec 31, 2022 | 57.29% |
| Sep 30, 2022 | 71.61% |
| Jun 30, 2022 | 70.66% |
| Mar 31, 2022 | 75.89% |
| Dec 31, 2021 | 72.22% |
| Sep 30, 2021 | 81.32% |