Codexis (CDXS) Gross Margin (2010 - 2026)

Codexis' (CDXS) quarterly Gross Margin came in at 86.46% in Q1 2026, up 2268.0% year-on-year from 3.65% in Q1 2025, and down 8.75% quarter-over-quarter from 94.75% in Q4 2025.

Codexis (CDXS) Gross Margin (2010 - 2026) Analysis & Trends

Codexis' Gross Margin history runs 17 years deep, the most recent figure standing at 86.46% for Q1 2026.

  • On a quarterly basis, Gross Margin rose 2268.0% year-over-year to 86.46% in Q1 2026; TTM through Mar 2026 was 88.9%, a 1733.0% increase from a year earlier, with the FY2025 full-year figure at 86.73%, up 1418.0% from the prior year.
  • Gross Margin fell to 86.46% in Q1 2026 per CDXS's latest filing, from 94.75% in the prior quarter.
  • Across five years, Gross Margin topped out at 94.75% in Q4 2025 and bottomed at 36.44% in Q2 2023.
  • The 5-year median for Gross Margin is 71.34% (2025), against an average of 69.16%.
  • Across the five-year window, Gross Margin sank 3422 bps in 2023 and surged 4021 bps in 2024, its largest moves.
  • Year by year, Gross Margin stood at 57.29% in 2022, then fell by 25 bps to 42.76% in 2023, then soared by 94 bps to 82.97% in 2024, then increased by 14 bps to 94.75% in 2025, then fell by 9 bps to 86.46% in 2026.
  • Per Business Quant, the three latest CDXS Gross Margin figures stand at 86.46% (Q1 2026), 94.75% (Q4 2025), and 71.34% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 67,102.16 Bn 67,101.87 Bn - -
2 Nanobiotix 1,913.50 Bn 1,913.44 Bn - -
3 Akari Therapeutics 959.56 Bn 959.56 Bn - -
4 BeOne Medicines 473.74 Bn 468.95 Bn 1.35 Bn 88.95%
5 Vertex Pharmaceuticals 122.07 Bn 114.82 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 70.00 Bn 61.24 Bn 3.31 Bn 91.79%
7 Belite Bio 62.34 Bn 62.34 Bn - -
8 Argenx Se 55.96 Bn 50.77 Bn 1.41 Bn 90.68%
9 Alnylam Pharmaceuticals 37.49 Bn 34.48 Bn 959.66 Mn 82.22%
10 Codexis 139.78 Mn 74.64 Mn 13.18 Mn 86.46%

Historic Data

Download Data
DateValue
Mar 31, 2026 86.46%
Dec 31, 2025 94.75%
Sep 30, 2025 71.34%
Jun 30, 2025 86.31%
Mar 31, 2025 63.78%
Dec 31, 2024 82.97%
Sep 30, 2024 66.36%
Jun 30, 2024 56.61%
Mar 31, 2024 71.56%
Dec 31, 2023 42.76%
Sep 30, 2023 75.76%
Jun 30, 2023 36.44%
Mar 31, 2023 65.17%
Dec 31, 2022 57.29%
Sep 30, 2022 71.61%
Jun 30, 2022 70.66%
Mar 31, 2022 75.89%
Dec 31, 2021 72.22%
Sep 30, 2021 81.32%
Jun 30, 2021 83.04%