Codexis (CDXS) Gross Margin (2010 - 2026)
Codexis' (CDXS) quarterly Gross Margin came in at 86.46% in Q1 2026, up 2268.0% year-on-year from 3.65% in Q1 2025, and down 8.75% quarter-over-quarter from 94.75% in Q4 2025.
Codexis (CDXS) Gross Margin (2010 - 2026) Analysis & Trends
Codexis' Gross Margin history runs 17 years deep, the most recent figure standing at 86.46% for Q1 2026.
- On a quarterly basis, Gross Margin rose 2268.0% year-over-year to 86.46% in Q1 2026; TTM through Mar 2026 was 88.9%, a 1733.0% increase from a year earlier, with the FY2025 full-year figure at 86.73%, up 1418.0% from the prior year.
- Gross Margin fell to 86.46% in Q1 2026 per CDXS's latest filing, from 94.75% in the prior quarter.
- Across five years, Gross Margin topped out at 94.75% in Q4 2025 and bottomed at 36.44% in Q2 2023.
- The 5-year median for Gross Margin is 71.34% (2025), against an average of 69.16%.
- Across the five-year window, Gross Margin sank 3422 bps in 2023 and surged 4021 bps in 2024, its largest moves.
- Year by year, Gross Margin stood at 57.29% in 2022, then fell by 25 bps to 42.76% in 2023, then soared by 94 bps to 82.97% in 2024, then increased by 14 bps to 94.75% in 2025, then fell by 9 bps to 86.46% in 2026.
- Per Business Quant, the three latest CDXS Gross Margin figures stand at 86.46% (Q1 2026), 94.75% (Q4 2025), and 71.34% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,102.16 Bn | 67,101.87 Bn | - | - |
| 2 | Nanobiotix | 1,913.50 Bn | 1,913.44 Bn | - | - |
| 3 | Akari Therapeutics | 959.56 Bn | 959.56 Bn | - | - |
| 4 | BeOne Medicines | 473.74 Bn | 468.95 Bn | 1.35 Bn | 88.95% |
| 5 | Vertex Pharmaceuticals | 122.07 Bn | 114.82 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 70.00 Bn | 61.24 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 62.34 Bn | 62.34 Bn | - | - |
| 8 | Argenx Se | 55.96 Bn | 50.77 Bn | 1.41 Bn | 90.68% |
| 9 | Alnylam Pharmaceuticals | 37.49 Bn | 34.48 Bn | 959.66 Mn | 82.22% |
| 10 | Codexis | 139.78 Mn | 74.64 Mn | 13.18 Mn | 86.46% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 86.46% |
| Dec 31, 2025 | 94.75% |
| Sep 30, 2025 | 71.34% |
| Jun 30, 2025 | 86.31% |
| Mar 31, 2025 | 63.78% |
| Dec 31, 2024 | 82.97% |
| Sep 30, 2024 | 66.36% |
| Jun 30, 2024 | 56.61% |
| Mar 31, 2024 | 71.56% |
| Dec 31, 2023 | 42.76% |
| Sep 30, 2023 | 75.76% |
| Jun 30, 2023 | 36.44% |
| Mar 31, 2023 | 65.17% |
| Dec 31, 2022 | 57.29% |
| Sep 30, 2022 | 71.61% |
| Jun 30, 2022 | 70.66% |
| Mar 31, 2022 | 75.89% |
| Dec 31, 2021 | 72.22% |
| Sep 30, 2021 | 81.32% |
| Jun 30, 2021 | 83.04% |