Codexis (CDXS) EBITDA Margin (2010 - 2026)
Codexis (CDXS) recorded quarterly EBITDA Margin of 52.75% in Q1 2026, down 294.4% quarter-over-quarter from 27.13% in Q4 2025, and up 21884.0% on a YoY basis from N/an in Q1 2025.
Codexis (CDXS) EBITDA Margin (2010 - 2026) Analysis & Trends
Codexis' EBITDA Margin history runs 17 years deep, the most recent figure standing at 52.75% for Q1 2026.
- In Q1 2026, EBITDA Margin rose 21884.0% year-over-year to 52.75%; the TTM figure through Mar 2026 stood at 37.51% (up 9722.0% YoY), while the FY2025 annual figure was 59.3%, up 3931.0% from the prior year.
- EBITDA Margin was 52.75% for Q1 2026 at Codexis, down from 27.13% in the prior quarter.
- In the past five years, EBITDA Margin ranged from a high of 27.13% in Q4 2025 to a low of 345.59% in Q3 2023.
- Historically, EBITDA Margin has averaged 118.96% across 5 years, with a median of 69.63% in 2024.
- The sharpest annual moves came in 2023 and 2026: EBITDA Margin sank 31473 bps in 2023, then soared 21884 bps in 2026.
- A 5-year view of EBITDA Margin shows it stood at 66.92% in 2022, then surged by 108 bps to 5.62% in 2023, then slumped by 709 bps to 34.21% in 2024, then soared by 179 bps to 27.13% in 2025, then sank by 294 bps to 52.75% in 2026.
- The last three EBITDA Margin figures came in at 52.75% (Q1 2026), 27.13% (Q4 2025), and 220.31% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | - |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | - |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | - |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | -6.43% |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | - |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | - |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | - |
| 10 | Codexis | 236.00 Mn | 170.86 Mn | 13.18 Mn | -52.75% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -52.75% |
| Dec 31, 2025 | 27.13% |
| Sep 30, 2025 | -220.31% |
| Jun 30, 2025 | -83.91% |
| Mar 31, 2025 | -271.59% |
| Dec 31, 2024 | -34.21% |
| Sep 30, 2024 | -129.02% |
| Jun 30, 2024 | -284.90% |
| Mar 31, 2024 | -69.63% |
| Dec 31, 2023 | 5.62% |
| Sep 30, 2023 | -345.59% |
| Jun 30, 2023 | -252.52% |
| Mar 31, 2023 | -182.29% |
| Dec 31, 2022 | -66.92% |
| Sep 30, 2022 | -30.86% |
| Jun 30, 2022 | -6.79% |
| Mar 31, 2022 | -23.73% |
| Dec 31, 2021 | -42.39% |
| Sep 30, 2021 | 3.62% |
| Jun 30, 2021 | -17.62% |