Growth Metrics

CareDx (CDNA) Return on Sales (2016 - 2025)

CareDx (CDNA) has disclosed Return on Sales for 13 consecutive years, with 0.04% as the latest value for Q4 2025.

  • Quarterly Return on Sales fell 105.0% to 0.04% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 0.06% through Dec 2025, down 21.0% year-over-year, with the annual reading at 0.06% for FY2025, 21.0% down from the prior year.
  • Return on Sales hit 0.04% in Q4 2025 for CareDx, down from 0.02% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 1.01% in Q4 2024 to a low of 1.8% in Q4 2023.
  • Historically, Return on Sales has averaged 0.19% across 5 years, with a median of 0.18% in 2021.
  • Biggest five-year swings in Return on Sales: plummeted -158bps in 2023 and later surged 281bps in 2024.
  • Year by year, Return on Sales stood at 0.2% in 2021, then fell by -9bps to 0.22% in 2022, then crashed by -709bps to 1.8% in 2023, then surged by 156bps to 1.01% in 2024, then crashed by -104bps to 0.04% in 2025.
  • Business Quant data shows Return on Sales for CDNA at 0.04% in Q4 2025, 0.02% in Q3 2025, and 0.1% in Q2 2025.