Growth Metrics

CareDx (CDNA) Return on Sales (2016 - 2025)

CareDx's Return on Sales history spans 13 years, with the latest figure at 0.04% for Q4 2025.

  • For Q4 2025, Return on Sales fell 105.0% year-over-year to 0.04%; the TTM value through Dec 2025 reached 0.06%, down 22.0%, while the annual FY2025 figure was 0.06%, 21.0% down from the prior year.
  • Return on Sales for Q4 2025 was 0.04% at CareDx, down from 0.02% in the prior quarter.
  • Across five years, Return on Sales topped out at 1.01% in Q4 2024 and bottomed at 3.2% in Q2 2023.
  • The 5-year median for Return on Sales is 0.18% (2021), against an average of 0.33%.
  • The largest annual shift saw Return on Sales tumbled -293bps in 2023 before it skyrocketed 315bps in 2024.
  • A 5-year view of Return on Sales shows it stood at 0.2% in 2021, then decreased by -9bps to 0.22% in 2022, then tumbled by -709bps to 1.8% in 2023, then surged by 156bps to 1.01% in 2024, then tumbled by -104bps to 0.04% in 2025.
  • Per Business Quant, the three most recent readings for CDNA's Return on Sales are 0.04% (Q4 2025), 0.02% (Q3 2025), and 0.1% (Q2 2025).